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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Haemophilus influenzae F3031
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei163GTPUniRule annotation1
Binding sitei167GTPUniRule annotation1
Binding sitei211GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi26 – 30GTPUniRule annotation5
Nucleotide bindingi132 – 134GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHINF866630:G1GVS-1140-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:HIBPF_11320Imported
OrganismiHaemophilus influenzae F3031Imported
Taxonomic identifieri866630 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000006795 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 229TubulinInterPro annotationAdd BLAST212
Domaini231 – 352Tubulin_CInterPro annotationAdd BLAST122

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

E7A5D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYPEYPEYD NFNESGALIK VVGVGGGGGN AVNHMVMNMV KQEMGGTFVG
60 70 80 90 100
ESSLTSEEHG RIVFYAVNTD AQALRKSQVQ QTVQIGGETT KGLGAGANPN
110 120 130 140 150
IGRKAAEDDQ DEIRKMLEGA DMVFIAAGMG GGTGTGAAPV VAKIAKELGI
160 170 180 190 200
LTVAVVTKPF AFEGKKRMQF AELGIKDLSQ YVDSMIIIPN QQIQKVLPKN
210 220 230 240 250
AKLIDAFAAA NDVLRNSVMG ISDMITSPGL INVDFADVRT VMSVQGQAMI
260 270 280 290 300
GFGSAVGEPG AGRAEEAARL AVRNDLLEKI DLSNAQGILV NITAGMDLVF
310 320 330 340 350
EEFNIIGETI GSFASEEATV VVGTSLVPEM SDEIRVTIVA TGLGEIAGNE
360 370 380 390 400
PIQVVRQGLS TQNIEGKGRV NIVPELHRRE SVEVSRTASE EYQRPLDKPI
410 420
TDRLEAFKKN NFFNPAQREE N
Length:421
Mass (Da):44,991
Last modified:March 8, 2011 - v1
Checksum:iA16BC7FE1CBD64F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FQ670178 Genomic DNA Translation: CBY81262.1
RefSeqiWP_013526064.1, NC_014920.1

Genome annotation databases

KEGGihif:HIBPF_11320

Similar proteinsi

Entry informationi

Entry nameiE7A5D0_HAEIF
AccessioniPrimary (citable) accession number: E7A5D0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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