Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Phosphatidylcholine:ceramide cholinephosphotransferase 1

Gene

SGMS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylcholine:ceramide cholinephosphotransferase 1Imported
Submitted name:
Sphingomyelin synthase 1Imported
Gene namesi
Name:SGMS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:29799. SGMS1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei135 – 156HelicalSequence analysisAdd BLAST22
Transmembranei182 – 205HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198964.

PTM / Processingi

Proteomic databases

PeptideAtlasiE6ZCI6.

Expressioni

Gene expression databases

ExpressionAtlasiE6ZCI6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000354829.

Structurei

3D structure databases

ProteinModelPortaliE6ZCI6.
SMRiE6ZCI6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 70SAM (sterile alpha motif)InterPro annotationAdd BLAST64

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3058. Eukaryota.
ENOG410XNSC. LUCA.
GeneTreeiENSGT00390000001630.
HOVERGENiHBG102663.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
InterProiIPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PfamiPF00536. SAM_1. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6ZCI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEVVYWSPK KVADWLLENA MPEYCEPLEH FTGQDLINLT QEDFKKPPLC
60 70 80 90 100
RVSSDNGQRL LDMIETLKME HHLEAHKNGH ANGHLNIGVD IPTPDGSFSI
110 120 130 140 150
KIKPNGMPNG YRKEMIKIPM PELERSQYPM EWGKTFLAFL YALSCFVLTT
160 170 180 190 200
VMISVVHERV PPKEVQPPLP DTFFDHFNRV QWAFSICEIN GMILVGLWLI
210
QWLLLKYNFS ETGKPNCEE
Length:219
Mass (Da):25,346
Last modified:March 8, 2011 - v1
Checksum:iCEB5A4857EDA21CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069547 Genomic DNA. No translation available.
AL117341 Genomic DNA. No translation available.
AL596137 Genomic DNA. No translation available.
FN908045 mRNA. Translation: CBM42040.1.
UniGeneiHs.654698.

Genome annotation databases

EnsembliENST00000429490; ENSP00000406795; ENSG00000198964.
UCSCiuc021pqo.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069547 Genomic DNA. No translation available.
AL117341 Genomic DNA. No translation available.
AL596137 Genomic DNA. No translation available.
FN908045 mRNA. Translation: CBM42040.1.
UniGeneiHs.654698.

3D structure databases

ProteinModelPortaliE6ZCI6.
SMRiE6ZCI6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000354829.

Proteomic databases

PeptideAtlasiE6ZCI6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000429490; ENSP00000406795; ENSG00000198964.
UCSCiuc021pqo.2. human.

Organism-specific databases

CTDi259230.
HGNCiHGNC:29799. SGMS1.
OpenTargetsiENSG00000198964.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3058. Eukaryota.
ENOG410XNSC. LUCA.
GeneTreeiENSGT00390000001630.
HOVERGENiHBG102663.

Miscellaneous databases

ChiTaRSiSGMS1. human.
GenomeRNAii259230.

Gene expression databases

ExpressionAtlasiE6ZCI6. baseline and differential.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
InterProiIPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PfamiPF00536. SAM_1. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE6ZCI6_HUMAN
AccessioniPrimary (citable) accession number: E6ZCI6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 2, 2016
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.