Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E6WZ35

- E6WZ35_NITSE

UniProt

E6WZ35 - E6WZ35_NITSE

Protein

Alanine racemase

Gene

Nitsa_0213

Organism
Nitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei33 – 331Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei116 – 1161SubstrateUniRule annotation
    Active sitei243 – 2431Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei289 – 2891Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciNSAL749222:GHWN-227-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Nitsa_0213Imported
    OrganismiNitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1)Imported
    Taxonomic identifieri749222 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesNitratifractor
    ProteomesiUP000008633: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei33 – 331N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE6WZ35.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031446.
    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E6WZ35-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAYILIDRGN FYHNLNQLAL KAGSKDRLAV VLKDNAYGHG LRLMGELSRD    50
    YGIREAVVVT NDEADQISDL FDHILVLGDS PRPSSRCSYA VSEIGLLRWI 100
    EPGVLIELKV DTGMHRNGIE PERLEEALEI IRKRKLRLFG VITHYRSADE 150
    LTSEYFWQKK RFDEVKKRVI DAGFSETRFH SHNSAALLRC RNFDEDIARV 200
    GIAIYGYNTL PKGFEGVELK PVLSLWARRA STRRLQEGAR IGYGGEFTAD 250
    REMPVSTYDL GYGDGWPRGR ASEPYRTAEG KAILGRVSMD FISVEGEADR 300
    ICVMEDARRA ARHFGTICYE MTTALMPTIP RRVVD 335
    Length:335
    Mass (Da):38,010
    Last modified:March 8, 2011 - v1
    Checksum:i82F0A385DE74D03D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002452 Genomic DNA. Translation: ADV45485.1.
    RefSeqiYP_004167234.1. NC_014935.1.

    Genome annotation databases

    EnsemblBacteriaiADV45485; ADV45485; Nitsa_0213.
    GeneIDi10146985.
    KEGGinsa:Nitsa_0213.
    PATRICi46981949. VBINitSal150288_0214.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002452 Genomic DNA. Translation: ADV45485.1 .
    RefSeqi YP_004167234.1. NC_014935.1.

    3D structure databases

    ProteinModelPortali E6WZ35.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADV45485 ; ADV45485 ; Nitsa_0213 .
    GeneIDi 10146985.
    KEGGi nsa:Nitsa_0213.
    PATRICi 46981949. VBINitSal150288_0214.

    Phylogenomic databases

    HOGENOMi HOG000031446.
    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci NSAL749222:GHWN-227-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 16511 / JCM 12458 / E9I37-1Imported.

    Entry informationi

    Entry nameiE6WZ35_NITSE
    AccessioniPrimary (citable) accession number: E6WZ35
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3