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E6WFA0 (E6WFA0_PANSA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU000608 HAMAP-Rule MF_01201

EC=5.1.1.1 RuleBase RU000608 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:Pat9b_2211 EMBL ADU69521.1
OrganismPantoea sp. (strain At-9b) [Complete proteome] [HAMAP] EMBL ADU69521.1
Taxonomic identifier592316 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePantoea

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3011Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E6WFA0 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: D96070900FC77FD4

FASTA35638,771
        10         20         30         40         50         60 
MSRPIVATIN QQALRHNLAV VRQAAPASRI WSVVKANAYG HGIRRVWQSL AETDGFALLN 

        70         80         90        100        110        120 
MEEAILLREQ GWKKPILLLE GFFHAEDLQL IDRYRLTTSV HSNWQIQALA QAQLSAPIDI 

       130        140        150        160        170        180 
YVKVNSGMNR LGFRPEQVNA AWQALRGLAN VGEMTLMAHF ADAENPQGII EPMKRIERAA 

       190        200        210        220        230        240 
EGLNCPRSLS NSAATLWHPE AHFDWVRPGI VLYGASPSGN WQDIASTGLT PVMTLTSEII 

       250        260        270        280        290        300 
GIQQLQAGDG VGYGYRYHAS AAQRIGVVAC GYADGYPRHA PTGTPVSVDG VMTRTVGAIS 

       310        320        330        340        350 
MDMIMIDLEP CPQAGIGSKV ELWGEQVKID DVAKAAGTVG YELMCALAPR VPVEII 

« Hide

References

[1]"Complete sequence chromosome of Pantoea sp. At-9b."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pinto A., Currie C., Woyke T.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: At-9b EMBL ADU69521.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002433 Genomic DNA. Translation: ADU69521.1.
RefSeqYP_004116077.1. NC_014837.1.

3D structure databases

ProteinModelPortalE6WFA0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU69521; ADU69521; Pat9b_2211.
GeneID10069647.
KEGGpao:Pat9b_2211.
PATRIC45318782. VBIPanSp129740_2206.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031446.
KOK01775.
OMAYGHGLER.

Enzyme and pathway databases

BioCycPSP592316:GI0L-2268-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE6WFA0_PANSA
AccessionPrimary (citable) accession number: E6WFA0
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)