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E6WFA0

- E6WFA0_PANSA

UniProt

E6WFA0 - E6WFA0_PANSA

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Protein

Alanine racemase

Gene

Pat9b_2211

Organism
Pantoea sp. (strain At-9b)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei35 – 351Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei130 – 1301SubstrateUniRule annotation
Active sitei253 – 2531Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei301 – 3011Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPSP592316:GI0L-2268-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Pat9b_2211Imported
OrganismiPantoea sp. (strain At-9b)Imported
Taxonomic identifieri592316 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePantoea
ProteomesiUP000001624: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei35 – 351N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE6WFA0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.
OMAiYGHGLER.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6WFA0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRPIVATIN QQALRHNLAV VRQAAPASRI WSVVKANAYG HGIRRVWQSL
60 70 80 90 100
AETDGFALLN MEEAILLREQ GWKKPILLLE GFFHAEDLQL IDRYRLTTSV
110 120 130 140 150
HSNWQIQALA QAQLSAPIDI YVKVNSGMNR LGFRPEQVNA AWQALRGLAN
160 170 180 190 200
VGEMTLMAHF ADAENPQGII EPMKRIERAA EGLNCPRSLS NSAATLWHPE
210 220 230 240 250
AHFDWVRPGI VLYGASPSGN WQDIASTGLT PVMTLTSEII GIQQLQAGDG
260 270 280 290 300
VGYGYRYHAS AAQRIGVVAC GYADGYPRHA PTGTPVSVDG VMTRTVGAIS
310 320 330 340 350
MDMIMIDLEP CPQAGIGSKV ELWGEQVKID DVAKAAGTVG YELMCALAPR

VPVEII
Length:356
Mass (Da):38,771
Last modified:March 8, 2011 - v1
Checksum:iD96070900FC77FD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002433 Genomic DNA. Translation: ADU69521.1.
RefSeqiWP_013509377.1. NC_014837.1.
YP_004116077.1. NC_014837.1.

Genome annotation databases

EnsemblBacteriaiADU69521; ADU69521; Pat9b_2211.
GeneIDi10069647.
KEGGipao:Pat9b_2211.
PATRICi45318782. VBIPanSp129740_2206.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002433 Genomic DNA. Translation: ADU69521.1 .
RefSeqi WP_013509377.1. NC_014837.1.
YP_004116077.1. NC_014837.1.

3D structure databases

ProteinModelPortali E6WFA0.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADU69521 ; ADU69521 ; Pat9b_2211 .
GeneIDi 10069647.
KEGGi pao:Pat9b_2211.
PATRICi 45318782. VBIPanSp129740_2206.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.
OMAi YGHGLER.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PSP592316:GI0L-2268-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence chromosome of Pantoea sp. At-9b."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Pinto A., Currie C., Woyke T.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: At-9bImported.

Entry informationi

Entry nameiE6WFA0_PANSA
AccessioniPrimary (citable) accession number: E6WFA0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 26, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3