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Protein

ATP-dependent Clp protease ATP-binding subunit ClpX

Gene

clpX

Organism
Rhodopseudomonas palustris (strain DX-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri15 – 40C4-typeUniRule annotationAdd BLAST26
Nucleotide bindingi119 – 126ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation, Hydrolase, ProteaseImported
LigandATP-bindingUniRule annotationSAAS annotationImported, Metal-binding, Nucleotide-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent Clp protease ATP-binding subunit ClpXUniRule annotationSAAS annotation
Gene namesi
Name:clpXUniRule annotation
Ordered Locus Names:Rpdx1_2480Imported
OrganismiRhodopseudomonas palustris (strain DX-1)Imported
Taxonomic identifieri652103 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001402 Componenti: Chromosome

Interactioni

Subunit structurei

Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.UniRule annotationSAAS annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi652103.Rpdx1_2480.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 51zf-C4_ClpXInterPro annotationAdd BLAST40
Domaini110 – 262AAAInterPro annotationAdd BLAST153
Domaini314 – 409ClpB_D2-smallInterPro annotationAdd BLAST96

Sequence similaritiesi

Belongs to the ClpX chaperone family.UniRule annotationSAAS annotation

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri15 – 40C4-typeUniRule annotationAdd BLAST26

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CHN. Bacteria.
COG1219. LUCA.
HOGENOMiHOG000010093.
KOiK03544.
OMAiDIMYDLP.
OrthoDBiPOG091H01U4.

Family and domain databases

HAMAPiMF_00175. ClpX. 1 hit.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR010603. Znf_CppX_C4.
PANTHERiPTHR11262. PTHR11262. 1 hit.
PfamiView protein in Pfam
PF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00382. clpX. 1 hit.

Sequencei

Sequence statusi: Complete.

E6VFH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKVGTSDSK NTLYCSFCGK SQHEVRKLIA GPTVFICDEC VELCMDIIRE
60 70 80 90 100
ENKSSLVKSR DGIPTPKEIC KVLDDYVIGQ GHAKKVLSVA VHNHYKRLNH
110 120 130 140 150
QTKHNDVELA KSNILLIGPT GSGKTLLAQT LARILDVPFT MADATTLTEA
160 170 180 190 200
GYVGEDVENI ILKLLQAADY NVERAQRGIV YIDEIDKISR KSDNPSITRD
210 220 230 240 250
VSGEGVQQAL LKIMEGTVAS VPPQGGRKHP QQEFLQVDTT NILFICGGAF
260 270 280 290 300
AGLEKIISGR GRSTSIGFAA QVLAPEDRRT GEIFRHVEPE DLLKYGLIPE
310 320 330 340 350
FVGRLPVVAT LEDLDETSLK KILTDPKNAL VKQYQRLFEM ENIELTFADE
360 370 380 390 400
ALGAVARKAI ERKTGARGLR SILESILLET MFDLPGLEGV EEVVISREVV
410 420
EGTARPLYIY ADRTDRAAET SASA
Length:424
Mass (Da):46,594
Last modified:March 8, 2011 - v1
Checksum:i01E731BB45FA4F6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002418 Genomic DNA. Translation: ADU44071.1.
RefSeqiWP_013502196.1. NC_014834.1.

Genome annotation databases

EnsemblBacteriaiADU44071; ADU44071; Rpdx1_2480.
KEGGirpx:Rpdx1_2480.

Similar proteinsi

Entry informationi

Entry nameiE6VFH9_RHOPX
AccessioniPrimary (citable) accession number: E6VFH9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 27, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported