ID   E6VBL8_RHOPX            Unreviewed;       613 AA.
AC   E6VBL8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE            EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN   OrderedLocusNames=Rpdx1_0962 {ECO:0000313|EMBL:ADU42590.1};
OS   Rhodopseudomonas palustris (strain DX-1).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Rhodopseudomonas.
OX   NCBI_TaxID=652103 {ECO:0000313|EMBL:ADU42590.1, ECO:0000313|Proteomes:UP000001402};
RN   [1] {ECO:0000313|Proteomes:UP000001402}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DX-1 {ECO:0000313|Proteomes:UP000001402};
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Misra M., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ivanova N., Ovchinnikova G., Logan B., Oda Y., Harwood C.,
RA   Woyke T.;
RT   "Complete sequence of Rhodopseudomonas palustris DX-1.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC         (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC         diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR   EMBL; CP002418; ADU42590.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6VBL8; -.
DR   STRING; 652103.Rpdx1_0962; -.
DR   KEGG; rpx:Rpdx1_0962; -.
DR   eggNOG; COG1793; Bacteria.
DR   HOGENOM; CLU_005138_6_2_5; -.
DR   OrthoDB; 9767858at2; -.
DR   BioCyc; RPAL652103:RPDX1_RS04770-MONOMER; -.
DR   Proteomes; UP000001402; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR   CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR   Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR   PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR   PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ADU42590.1}.
FT   DOMAIN          361..498
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50160"
FT   REGION          91..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   613 AA;  67838 MW;  06F73C0CD090A228 CRC64;
     MNRFAELLDR LGYEPGRNNK LRLITNYFRA VEDPDRGWAL AALTGALSFR HAKPGLIRAL
     IAERTDPVLF GLSYDYVGDL SETVALMWPS PHAQRNSPPP CGEGSGVGVH TGTPSSGRPH
     PNPLPQAGEG VRCASGEDVA SAEGSVNTGH NNPPPPTLTE IVTTLHSLGK AELPAQLARW
     LDELDETGRW ALLKLVTGAL RIGVSARLAK TAAAALGNKD PHDVELVWPG IEPPYDELFA
     WLEGRGPQPA SRDPAPFRPV MLAHAVDDTD FAGMDPADYI AEWKWDGIRV QAVSGLNEHG
     DCVVRLYSRS GEDITMSFPD LLPSLRLPGA IDGELLVLRD KRVQSFNVLQ QRLNRKSVTP
     KLTKDYPIHL RAYDLLGDGD EDLRTLPFAE RRTRLETLIA RLGDPKVDLS PIVAFDDWDG
     LRAARRDPAS AGAGLDADAV EGVMLKRRDA PYLPGRPKGQ WWKWKHDPHI IDAVLMYAQR
     GHGKRSSYYS DYTFGVWTEG DGGDQLVPVG KAYFGFTDEE LLQIDRFVRR NTTEKFGPVR
     HVVHEPDKGL VLEVAFEGLQ RSPRHKSGVA MRFPRISRLR WDKPPKDADR LETLERMLKA
     ESAKPHPAGA RGH
//