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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Variovorax paradoxus (strain EPS)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei154UniRule annotation1
Active sitei599UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciVPAR595537:G1GQO-1524-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Varpa_1512Imported
OrganismiVariovorax paradoxus (strain EPS)Imported
Taxonomic identifieri595537 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeVariovorax
Proteomesi
  • UP000008917 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi595537.Varpa_1512

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

E6V2K2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKASKTPALP KRRQAEDQPL IDDIRLLGRI LGDVIREQEG DETYALVEKI
60 70 80 90 100
RTLSVAFRRD ADQAADRALK NLLKGLSAAE TVRVIRAFTY FSHLANLAED
110 120 130 140 150
RHQIRRRTEA DREGVLADGD LQTALARIRK AGVKPDEIVA SLAHSYVSPV
160 170 180 190 200
LTAHPTEVQR KSILDAERAI ALLLTTRDEI KLRQSAYASG KDALSPIELA
210 220 230 240 250
DNETQMRTRV TQIWQTRLLR FSKLTVADEI ENALSYYEAT FLREIPRVYA
260 270 280 290 300
DLEKALTQGG HTPSVAPFLR MGQWIGGDRD GNPNVTAETL EYALGRQAEL
310 320 330 340 350
ALRLYLTEVH YLGGELSLSA TLVDVSVEMQ ALAERSPDTS EHRKDEPYRR
360 370 380 390 400
ALTGVYARLA ATLRELTGGE AARHAVAPQN PYAKAEEFLA DLRTVEESLG
410 420 430 440 450
EKHGSVLAAP RLRPLIRAVE VFGFHLATVD LRQSSDKHEA VIAELLATAR
460 470 480 490 500
IEPSYASLAE EAKQTLLLKL LDDARPLRVP DADYSPLAKS ELAIFAAART
510 520 530 540 550
ARARYGAAAI RHYIISHTET VSDLLEALLL QKEVGLLRGA MATNAVCDLI
560 570 580 590 600
VVPLFETIED LRNAAPIVRA FYALPNIQAL IERSGGEQDV MLGYSDSNKD
610 620 630 640 650
GGIFTSNWEL YRAGIALVSL FDELNKKKAN PIRLRMFHGR GGTVGRGGGP
660 670 680 690 700
SYQAILAQPP GTVRGQIRLT EQGEVIGSKY ANREIGRRNL ETLVAATLEA
710 720 730 740 750
TLLPQGKSAP ATFLSAASEL SAASMAAYRK LVYETPGFGD YFFGSTPIRE
760 770 780 790 800
IAELNIGSRP ASRNPSHKID DLRAVPWSFS WGQCRLTIPG WFGFGAGVEQ
810 820 830 840 850
FLASAGNAAG KKERVALLQR MYAQWPFFRT LLSNMDMVLA KSDLALASRY
860 870 880 890 900
AELVTDRKLR QKVFSMIDAE WHRTSDALTL ITGAKQRLEG NAEMQRSVRH
910 920 930 940
RFPYIDPLHH LQVELMRRYR AGDGGERLQR GIHISINGVA AGLRNTG
Length:947
Mass (Da):104,659
Last modified:March 8, 2011 - v1
Checksum:i75A6A0E59497708E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002417 Genomic DNA Translation: ADU35723.1
RefSeqiWP_013539966.1, NC_014931.1

Genome annotation databases

EnsemblBacteriaiADU35723; ADU35723; Varpa_1512
GeneIDi29715570
KEGGivpe:Varpa_1512

Similar proteinsi

Entry informationi

Entry nameiE6V2K2_VARPE
AccessioniPrimary (citable) accession number: E6V2K2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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