Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

E6V191 (E6V191_VARPE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2541Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3021Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E6V191 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: FD05A9EFAC4C17FA

FASTA36639,803
        10         20         30         40         50         60 
MPRPILATVH TAALRNNLER VRRSALDARV WAVVKANAYG HGIERVYEGL RGADGFALLD 

        70         80         90        100        110        120 
LAEAERVRAL GWRGPVLLLE GVFDARDLEL CSRLDLWHTV HCDEQIDMLA AHKTLKPQRV 

       130        140        150        160        170        180 
FLKMNSGMNR LGFTPERFGS AWTRLNALTQ VDEISLMTHF SDADGARGIA HQLEAFERAT 

       190        200        210        220        230        240 
RDLPGERSIA NSAATLRHAD QTRGDWVRPG IVLYGSAPDF PLHDAAHWQL QPTMTLSTQL 

       250        260        270        280        290        300 
LSVQTLKAGD TIGYGSNFTA EGPLTIGVAA VGYADGYPRH CNTGTPVLVN GVRTRMVGRV 

       310        320        330        340        350        360 
SMDMITVDLT PVPDAKFGAE VTLWGRSAST GAVLPIDEVA QAAGTVGYEL MCAVAQRVPF 


AAPTDE 

« Hide

References

[1]"Complete sequence of Variovorax paradoxus EPS."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Orwin P., Han J.-I.G., Woyke T.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EPS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002417 Genomic DNA. Translation: ADU34455.1.
RefSeqYP_004152566.1. NC_014931.1.

3D structure databases

ProteinModelPortalE6V191.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU34455; ADU34455; Varpa_0233.
GeneID10127046.
KEGGvpe:Varpa_0233.
PATRIC45386341. VBIVarPar156291_0235.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000031446.
KOK01775.
OMARDLELCS.

Enzyme and pathway databases

BioCycVPAR595537:GHGJ-239-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE6V191_VARPE
AccessionPrimary (citable) accession number: E6V191
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: February 19, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)