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E6URL9 (E6URL9_CLOTL) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site411Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2701Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1391Substrate By similarity HAMAP-Rule MF_01201
Binding site3181Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue411N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
E6URL9 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: E8D3E5C6DD62681E

FASTA39143,669
        10         20         30         40         50         60 
MGMDYKFNRA WAEVNLDNIA HNVKEIRRIV DKKVEIMGVV KADAYGHGVM EIARTLLENG 

        70         80         90        100        110        120 
VTRLAVSMLD EAIQLRQNGI KVPILILSYT DPVRAEEIVL NDVTQTVFSH DLAEALSEAA 

       130        140        150        160        170        180 
VKHHRNVKIH IKIDTGMTRV GFMPGYSAVK NVVQISKLPG IIIEGLFTHF ASADEADKSY 

       190        200        210        220        230        240 
TYMQFERFMS IVGELNRIGV YIPVKHVCNS AALIEFPEMH LNMVRPGIAL YGLYPSDEVD 

       250        260        270        280        290        300 
KTKIDLRPAM SLKANVILVK DVEKDTFISY GRIFKTSRNS RIATIPIGYA DGYTRLLTGK 

       310        320        330        340        350        360 
GKVLLNGQLA PIVGRICMDQ CMVDITDIEG DVKVGDEAVL IGKQKDNEIK VEDLAKSVGT 

       370        380        390 
INYELVSIIG KRIPRVYLKE GKIYNVLNYL I 

« Hide

References

[1]"Complete genome sequence of the cellulolytic thermophile Clostridium thermocellum DSM1313."
Feinberg L., Foden J., Barrett T., Davenport K.W., Bruce D., Detter C., Tapia R., Han C., Lapidus A., Lucas S., Cheng J.F., Pitluck S., Woyke T., Ivanova N., Mikhailova N., Land M., Hauser L., Argyros D.A. expand/collapse author list , Goodwin L., Hogsett D., Caiazza N.
J. Bacteriol. 193:2906-2907(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 1313 / LMG 6656 / LQ8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002416 Genomic DNA. Translation: ADU73379.1.
RefSeqYP_005686830.1. NC_017304.1.

3D structure databases

ProteinModelPortalE6URL9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADU73379; ADU73379; Clo1313_0288.
GeneID12419986.
KEGGctx:Clo1313_0288.
PATRIC45475120. VBICloThe140364_0315.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMACIDEALT.

Enzyme and pathway databases

BioCycCTHE637887:GLBN-299-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE6URL9_CLOTL
AccessionPrimary (citable) accession number: E6URL9
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: February 19, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)