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E6URL9

- E6URL9_CLOTL

UniProt

E6URL9 - E6URL9_CLOTL

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Protein

Alanine racemase

Gene
Clo1313_0288
Organism
Clostridium thermocellum (strain DSM 1313 / LMG 6656 / LQ8)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei41 – 411Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei139 – 1391Substrate By similarityUniRule annotation
Active sitei270 – 2701Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei318 – 3181Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciCTHE637887:GLBN-299-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Clo1313_0288Imported
OrganismiClostridium thermocellum (strain DSM 1313 / LMG 6656 / LQ8)Imported
Taxonomic identifieri637887 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminiclostridium
ProteomesiUP000008083: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei41 – 411N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE6URL9.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01775.
OMAiRIGISIY.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6URL9-1 [UniParc]FASTAAdd to Basket

« Hide

MGMDYKFNRA WAEVNLDNIA HNVKEIRRIV DKKVEIMGVV KADAYGHGVM    50
EIARTLLENG VTRLAVSMLD EAIQLRQNGI KVPILILSYT DPVRAEEIVL 100
NDVTQTVFSH DLAEALSEAA VKHHRNVKIH IKIDTGMTRV GFMPGYSAVK 150
NVVQISKLPG IIIEGLFTHF ASADEADKSY TYMQFERFMS IVGELNRIGV 200
YIPVKHVCNS AALIEFPEMH LNMVRPGIAL YGLYPSDEVD KTKIDLRPAM 250
SLKANVILVK DVEKDTFISY GRIFKTSRNS RIATIPIGYA DGYTRLLTGK 300
GKVLLNGQLA PIVGRICMDQ CMVDITDIEG DVKVGDEAVL IGKQKDNEIK 350
VEDLAKSVGT INYELVSIIG KRIPRVYLKE GKIYNVLNYL I 391
Length:391
Mass (Da):43,669
Last modified:March 8, 2011 - v1
Checksum:iE8D3E5C6DD62681E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002416 Genomic DNA. Translation: ADU73379.1.
RefSeqiYP_005686830.1. NC_017304.1.

Genome annotation databases

EnsemblBacteriaiADU73379; ADU73379; Clo1313_0288.
GeneIDi12419986.
KEGGictx:Clo1313_0288.
PATRICi45475120. VBICloThe140364_0315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002416 Genomic DNA. Translation: ADU73379.1 .
RefSeqi YP_005686830.1. NC_017304.1.

3D structure databases

ProteinModelPortali E6URL9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADU73379 ; ADU73379 ; Clo1313_0288 .
GeneIDi 12419986.
KEGGi ctx:Clo1313_0288.
PATRICi 45475120. VBICloThe140364_0315.

Phylogenomic databases

KOi K01775.
OMAi RIGISIY.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CTHE637887:GLBN-299-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 1313 / LMG 6656 / LQ8.

Entry informationi

Entry nameiE6URL9_CLOTL
AccessioniPrimary (citable) accession number: E6URL9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 3, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi