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E6UD01

- E6UD01_RUMA7

UniProt

E6UD01 - E6UD01_RUMA7

Protein

Alanine racemase

Gene

Rumal_0238

Organism
Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei38 – 381Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei134 – 1341SubstrateUniRule annotation
    Active sitei268 – 2681Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei316 – 3161Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciRALB697329:GIWQ-244-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Rumal_0238Imported
    OrganismiRuminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)Imported
    Taxonomic identifieri697329 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus
    ProteomesiUP000006919: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei38 – 381N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE6UD01.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000031444.
    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E6UD01-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNFLRRCWAE IDLSAVDYNV CEYKKLLPQD TELMCVVKAS CYGHSDELIV    50
    PRLQQVHGVR YFAVSNILEG IRLREIGING DILILGYTPP ECAAELVKYD 100
    IIQACTELCY AQELSANANG TVRLHGAVDT GMTRIGVHGT AEEQADELAK 150
    VSALPNISLE GIFTHFSSAD GIDDADEKYT QMQSERFFRV RDLLKEKGIR 200
    LKHAHIKNSA GGAYGYGDES TLARLGIILY GLYPDPAKSL PFVPKPVMTL 250
    KAVVSQVKWI DEGTAVSYGR TFVSDRRMKL ATVTAGYADG YPRALSNKGE 300
    VIIRGKKCRI CGRVCMDQFM CDVTDIPDAA PGDEVILMNA EINADVIAAL 350
    TGTIGYEITC DITSRVPRVP VNS 373
    Length:373
    Mass (Da):40,970
    Last modified:March 8, 2011 - v1
    Checksum:i6EDD22E59419B162
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002403 Genomic DNA. Translation: ADU20795.1.
    RefSeqiYP_004103429.1. NC_014833.1.

    Genome annotation databases

    EnsemblBacteriaiADU20795; ADU20795; Rumal_0238.
    GeneIDi10076468.
    KEGGiral:Rumal_0238.
    PATRICi45356795. VBIRumAlb150544_0959.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002403 Genomic DNA. Translation: ADU20795.1 .
    RefSeqi YP_004103429.1. NC_014833.1.

    3D structure databases

    ProteinModelPortali E6UD01.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADU20795 ; ADU20795 ; Rumal_0238 .
    GeneIDi 10076468.
    KEGGi ral:Rumal_0238.
    PATRICi 45356795. VBIRumAlb150544_0959.

    Phylogenomic databases

    HOGENOMi HOG000031444.
    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci RALB697329:GIWQ-244-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7Imported.

    Entry informationi

    Entry nameiE6UD01_RUMA7
    AccessioniPrimary (citable) accession number: E6UD01
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3