Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

E6TSX6

- E6TSX6_BACCJ

UniProt

E6TSX6 - E6TSX6_BACCJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO

Gene

trmFO

Organism
Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.UniRule annotationSAAS annotation

Catalytic activityi

5,10-methylenetetrahydrofolate + uracil(54) in tRNA + FADH2 = tetrahydrofolate + 5-methyluracil(54) in tRNA + FAD.UniRule annotationSAAS annotation

Cofactori

FAD.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi9 – 146FADUniRule annotation

GO - Molecular functioni

  1. 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity Source: UniProtKB-HAMAP
  2. flavin adenine dinucleotide binding Source: UniProtKB-HAMAP
  3. methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

tRNA processingUniRule annotationSAAS annotation

Keywords - Ligandi

FADUniRule annotationSAAS annotation, Flavoprotein

Enzyme and pathway databases

BioCyciBCEL649639:GHTT-2592-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFOUniRule annotation (EC:2.1.1.74UniRule annotation)
Alternative name(s):
Folate-dependent tRNA (uracil-5-)-methyltransferaseUniRule annotation
Folate-dependent tRNA(M-5-U54)-methyltransferaseUniRule annotation
Gene namesi
Name:trmFOUniRule annotation
Ordered Locus Names:Bcell_2511Imported
OrganismiBacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)Imported
Taxonomic identifieri649639 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001401: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliE6TSX6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family. TrmFO subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000252054.
KOiK04094.
OMAiEIYFEGC.

Family and domain databases

HAMAPiMF_01037. TrmFO.
InterProiIPR004417. Folate-dep_Ribothymidyl_synth.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00137. gid_trmFO. 1 hit.
PROSITEiPS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6TSX6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQHVNVIGA GLAGSEAAWQ IAKRGIPVHL YEMRPKKQTP AHHTDKFAEL
60 70 80 90 100
VCSNSLRANT LTNAVGVLKE EMRILDSVII QSADDCSVPA GGALAVDRHE
110 120 130 140 150
FAALVTERVK NHELVTVFED EVTEIPEGPT IICTGPLTSE SLSHRLKELT
160 170 180 190 200
GEEYLYFYDA AAPIIDADSI DRNKVYLKSR YDKGEAAYLN CPMTEEEFNT
210 220 230 240 250
FYDALIEAET VPVKEFEKEM FFEGCMPVEV MAKRGRKTLL FGPMKPVGLE
260 270 280 290 300
DPKTNKRPFA VVQLRQDNSS GTLFNIVGFQ THMKWGPQKE VIQLIPGLEN
310 320 330 340 350
AEIVRFGVMH RNTFINSPNL LKPTYQYRDR DDLFFAGQMT GVEGYVESAA
360 370 380 390 400
AGLVAGINAS RLIQEKETVT FPNETVIGSM AQYITTANHK NFQPMNANFG
410 420 430
LLPPFEQRIK NKQERNEKHA NRALETIQNF VKKM
Length:434
Mass (Da):48,678
Last modified:March 8, 2011 - v1
Checksum:i7D1F584A608BDA37
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002394 Genomic DNA. Translation: ADU30768.1.
RefSeqiWP_013489102.1. NC_014829.1.
YP_004095499.1. NC_014829.1.

Genome annotation databases

EnsemblBacteriaiADU30768; ADU30768; Bcell_2511.
GeneIDi10089084.
KEGGibco:Bcell_2511.
PATRICi45161012. VBIBacCel7049_2580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002394 Genomic DNA. Translation: ADU30768.1 .
RefSeqi WP_013489102.1. NC_014829.1.
YP_004095499.1. NC_014829.1.

3D structure databases

ProteinModelPortali E6TSX6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADU30768 ; ADU30768 ; Bcell_2511 .
GeneIDi 10089084.
KEGGi bco:Bcell_2511.
PATRICi 45161012. VBIBacCel7049_2580.

Phylogenomic databases

HOGENOMi HOG000252054.
KOi K04094.
OMAi EIYFEGC.

Enzyme and pathway databases

BioCyci BCEL649639:GHTT-2592-MONOMER.

Family and domain databases

HAMAPi MF_01037. TrmFO.
InterProi IPR004417. Folate-dep_Ribothymidyl_synth.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view ]
Pfami PF01134. GIDA. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00137. gid_trmFO. 1 hit.
PROSITEi PS01281. GIDA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Bacillus cellulosilyticus DSM 2522."
    Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N., Brumm P., Mead D., Woyke T.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4Imported.

Entry informationi

Entry nameiE6TSX6_BACCJ
AccessioniPrimary (citable) accession number: E6TSX6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: October 29, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3