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E6TF02

- E6TF02_MYCSR

UniProt

E6TF02 - E6TF02_MYCSR

Protein

Elongation factor Tu

Gene

tuf

Organism
Mycobacterium sp. (strain Spyr1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi83 – 875GTPUniRule annotation
    Nucleotide bindingi138 – 1414GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMSP278137:GHD6-4454-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Mspyr1_44930Imported
    OrganismiMycobacterium sp. (strain Spyr1)Imported
    Taxonomic identifieri278137 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000008916: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiE6TF02.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliE6TF02.
    SMRiE6TF02. Positions 2-395.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiISAPAAC.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E6TF02-1 [UniParc]FASTAAdd to Basket

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    MAKAKFERTK PHVNIGTIGH VDHGKTTLTA AITKVLHDQY PDLNESRAFD    50
    QIDNAPEERQ RGITINISHV EYQTEKRHYA HVDAPGHADY IKNMITGAAQ 100
    MDGAILVVAA TDGPMPQTRE HVLLARQVGV PYILVALNKA DMVDDEELIE 150
    LVEMEVRELL AAQDFDEDAP VVKVSALKAL EGDEKWVKSV QELMAAVDES 200
    IPDPVRETDK PFLMPVEDVF TITGRGTVVT GRVERGVINV NEEVEIVGIR 250
    PTVTKTTVTG VEMFRKLLDQ GQAGDNVGLL VRGIKREDVE RGQVVVKPGT 300
    TTPHTEFEGS VYILSKDEGG RHTPFFNNYR PQFYFRTTDV TGVVTLPEGT 350
    EMVMPGDNTD IAVKLIQPVA MDEGLRFAIR EGGRTVGAGR VTKIIK 396
    Length:396
    Mass (Da):43,698
    Last modified:March 8, 2011 - v1
    Checksum:i679BD506A0893E48
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002385 Genomic DNA. Translation: ADU01048.1.
    RefSeqiWP_011895899.1. NC_014814.1.
    YP_004078882.1. NC_014814.1.

    Genome annotation databases

    EnsemblBacteriaiADU01048; ADU01048; Mspyr1_44930.
    GeneIDi10048882.
    KEGGimsp:Mspyr1_44930.
    PATRICi45290202. VBIMycSp109077_4723.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002385 Genomic DNA. Translation: ADU01048.1 .
    RefSeqi WP_011895899.1. NC_014814.1.
    YP_004078882.1. NC_014814.1.

    3D structure databases

    ProteinModelPortali E6TF02.
    SMRi E6TF02. Positions 2-395.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E6TF02.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADU01048 ; ADU01048 ; Mspyr1_44930 .
    GeneIDi 10048882.
    KEGGi msp:Mspyr1_44930.
    PATRICi 45290202. VBIMycSp109077_4723.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi ISAPAAC.

    Enzyme and pathway databases

    BioCyci MSP278137:GHD6-4454-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Mycobacterium sp. Spyr1."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., LaButti K., Ivanova N.M., Mikhailova N.M., Land M., Hauser L., Koukkou A.I., Drainas C., Kyrpides N., Woyke T.
      Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Spyr1Imported.

    Entry informationi

    Entry nameiE6TF02_MYCSR
    AccessioniPrimary (citable) accession number: E6TF02
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3