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E6TCD8 (E6TCD8_MYCSR) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aspartate carbamoyltransferase HAMAP-Rule MF_00001
EC=2.1.3.2 HAMAP-Rule MF_00001
Alternative name(s):
Aspartate transcarbamylase HAMAP-Rule MF_00001
Gene names
Name:pyrB HAMAP-Rule MF_00001
Ordered Locus Names:Mspyr1_30880 EMBL ADT99705.1
OrganismMycobacterium sp. (strain Spyr1) [Complete proteome] [HAMAP] EMBL ADT99705.1
Taxonomic identifier278137 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium ›

Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP-Rule MF_00001

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP-Rule MF_00001

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP-Rule MF_00001 RuleBase RU003634

Sequences

Sequence LengthMass (Da)Tools
E6TCD8 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: 784CBD8C9EDC7D2A

FASTA31533,807
        10         20         30         40         50         60 
MKHLLTAADL SRDDATAILD NADRFREALV GREVKKLPTL RGRTIITMFY ENSTRTRVSF 

        70         80         90        100        110        120 
EVAGKWMSAD VINVSASGSS VAKGESLRDT ALTLRAAGAD ALIIRHPASG APQQLAAWTL 

       130        140        150        160        170        180 
DEHGGPSVIN AGDGTHEHPT QALLDALTIR QRLGSVEGKR VVIVGDVLHS RVARSNVALL 

       190        200        210        220        230        240 
HTLGAEVVLV APPTLLPVGV TEWPVTVSHE LDAELPLADA VLMLRVQAER MNGGFFPSSR 

       250        260        270        280        290        300 
EYSVRYGLSE KRQSTLAEHA VVLHPGPMLR GMEIAYSVAD SSQSAVLQQV SNGVHVRMAV 

       310 
LFHLLVGSEE EAISA

« Hide

References

[1]"Complete sequence of chromosome of Mycobacterium sp. Spyr1."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., Pitluck S., LaButti K., Ivanova N.M., Mikhailova N.M., Land M., Hauser L., Koukkou A.I., Drainas C., Kyrpides N., Woyke T.
Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Spyr1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002385 Genomic DNA. Translation: ADT99705.1.
RefSeqYP_004077540.1. NC_014814.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADT99705; ADT99705; Mspyr1_30880.
GeneID10047479.
KEGGmsp:Mspyr1_30880.
PATRIC45287344. VBIMycSp109077_3317.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000022685.
KOK00609.
OMAMTLNAMR.

Enzyme and pathway databases

BioCycMSP278137:GHD6-3068-MONOMER.
UniPathwayUPA00070; UER00116.

Family and domain databases

HAMAPMF_00001. Asp_carb_tr.
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMSSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMsTIGR00670. asp_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE6TCD8_MYCSR
AccessionPrimary (citable) accession number: E6TCD8
Entry history
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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