E6SSP2 (E6SSP2_BACT6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase EMBL ADV43155.1
EC=2.1.2.3 EMBL ADV43155.1
EC=3.5.4.10 EMBL ADV43155.1

Gene names

Ordered Locus Names:

Bache_1145

Organism

Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / P 36-108) [Complete proteome] [HAMAP] EMBL ADV43155.1

Taxonomic identifier

693979 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides › Bacteroides helcogenes

Protein attributes

Sequence length	507 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. SAAS SAAS024051 IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. SAAS SAAS024051
Pathway	Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. SAAS SAAS024051 Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1. SAAS SAAS024051

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS024051
Molecular function	Hydrolase SAAS SAAS024051 EMBL ADV43155.1 Transferase SAAS SAAS024051 EMBL ADV43155.1
Technical term	Complete proteome Multifunctional enzyme SAAS SAAS024051
Gene Ontology (GO)
Biological_process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	IMP cyclohydrolase activity Inferred from electronic annotation. Source: EC phosphoribosylaminoimidazolecarboxamide formyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E6SSP2 [UniParc]. Last modified March 8, 2011. Version 1. Checksum: 5EC49611EE5BA1D2	FASTA	507	55,616
	10 20 30 40 50 60 MSETKRIKTA LVSVYHKEGL DEIITKLHEE GVEFLSTGGT RQFIESLGYP CKAVEDLTSY 70 80 90 100 110 120 PSILGGRVKT LHPKVFGGIL CRRGLEQDMQ QIDKYEIPEI DLVIVDLYPF EATVAGGAEE 130 140 150 160 170 180 AAVIEKIDIG GISLIRAAAK NFNDVVIIAS QAQYQPFRDM LMEHGATTSL EERRWFAKEA 190 200 210 220 230 240 FAVSSHYDSA IFNYFDGEEG SAFRQSANNQ KMLRYGENPH QKGYFYGNLD AMFDQIHGKE 250 260 270 280 290 300 ISYNNLLDIN AAVDLIDEFG ETTFAILKHN NACGLASRPT VLEAWNDALA GDPVSAFGGV 310 320 330 340 350 360 LITNAVVDKA AAEEITKIFF EVIIAPDYDV DALEILGQKK NRIILVRKPA ALPKKQFRSL 370 380 390 400 410 420 LNGVLVQDRD LKVETSGDLK TVTAKTPAAG EIEDMLFANK IVKNSKSNAI VLAKGKQLLA 430 440 450 460 470 480 SGVGQTSRVD ALKQAIEKAK NFGFDLNGAV MASDAFFPFP DCVEIAGNEG VTAVIQPGGS 490 500 IKDELSFEYC NEHGIAMVIT GFRHFKH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome of Bacteroides helcogenes P 36-108." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Zeytun A., Brettin T., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F. , Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P., Eisen J.A. Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: P 36-108.
[2]	"Complete genome sequence of Bacteroides helcogenes type strain (P 36-108)." Pati A., Gronow S., Zeytun A., Lapidus A., Nolan M., Hammon N., Deshpande S., Cheng J., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K. , Land M., Hauser L., Chang Y., Jeffries C., Detter J., Brambilla E., Rohde M., Goker, M., Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P., Kyrpides N., Klenk H., Lucas S. Stand. Genomic Sci. 4:45-53(2011) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35417 / DSM 20613 / JCM 6297 / P 36-108.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002352 Genomic DNA. Translation: ADV43155.1.
RefSeq	YP_004160741.1. NC_014933.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADV43155; ADV43155; Bache_1145.
GeneID	10139904.
KEGG	bhl:Bache_1145.
PATRIC	45172776. VBIBacHel147569_1212.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000230373.
KO	K00602.
Enzyme and pathway databases
BioCyc	BHEL693979:GHID-1181-MONOMER.
UniPathway	UPA00074; UER00133. UPA00074; UER00135.
Family and domain databases
Gene3D	3.40.140.20. 2 hits. 3.40.50.1380. 1 hit.
InterPro	IPR024051. AICAR_Tfase_dom. IPR002695. AICARFT_IMPCHas. IPR016193. Cytidine_deaminase-like. IPR011607. MGS-like_dom. [Graphical view]
PANTHER	PTHR11692. PTHR11692. 1 hit.
Pfam	PF01808. AICARFT_IMPCHas. 1 hit. PF02142. MGS. 1 hit. [Graphical view]
PIRSF	PIRSF000414. AICARFT_IMPCHas. 1 hit.
SMART	SM00798. AICARFT_IMPCHas. 1 hit. SM00851. MGS. 1 hit. [Graphical view]
SUPFAM	SSF53927. Cytidine_deaminase-like. 1 hit. SSF52335. MGS-like_dom. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E6SSP2_BACT6

Accession

Primary (citable) accession number: E6SSP2

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	May 1, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)