ID   E6SN74_BACT6            Unreviewed;       545 AA.
AC   E6SN74;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Sialidase {ECO:0000313|EMBL:ADV44727.1};
GN   OrderedLocusNames=Bache_2784 {ECO:0000313|EMBL:ADV44727.1};
OS   Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / CCUG
OS   15421 / P 36-108).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=693979 {ECO:0000313|EMBL:ADV44727.1, ECO:0000313|Proteomes:UP000008630};
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=P 36-108;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Zeytun A., Brettin T., Detter J.C.,
RA   Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Bacteroides helcogenes P 36-108.";
RL   Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADV44727.1, ECO:0000313|Proteomes:UP000008630}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35417 / DSM 20613 / JCM 6297 / CCUG 15421 / P 36-108
RC   {ECO:0000313|Proteomes:UP000008630};
RX   PubMed=21475586; DOI=10.4056/sigs.1513795;
RA   Pati A., Gronow S., Zeytun A., Lapidus A., Nolan M., Hammon N.,
RA   Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA   Liolios K., Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brambilla E.,
RA   Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Lucas S.;
RT   "Complete genome sequence of Bacteroides helcogenes type strain (P 36-
RT   108).";
RL   Stand. Genomic Sci. 4:45-53(2011).
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DR   EMBL; CP002352; ADV44727.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6SN74; -.
DR   STRING; 693979.Bache_2784; -.
DR   KEGG; bhl:Bache_2784; -.
DR   PATRIC; fig|693979.3.peg.2915; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_0_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000008630; Chromosome.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   Gene3D; 2.60.40.1290; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR029456; Sialidase_N.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF19; SIALIDASE; 1.
DR   Pfam; PF13859; BNR_3; 1.
DR   Pfam; PF14873; BNR_assoc_N; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008630}.
FT   DOMAIN          24..173
FT                   /note="Sialidase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14873"
FT   DOMAIN          205..486
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13859"
SQ   SEQUENCE   545 AA;  60348 MW;  FBAB62851AB0A0EE CRC64;
     MKSFICFLAL FFQVCTLSAN DKMQDSIYIK EMYVPILIER IDNELFEIRI DAKESKMLDE
     LQLTFDEGVK ISEIEAVKLY YSGTEASNRK NANIFAPVDY ISSHKEGRTF AANSSYSILK
     SEVKSPKHNV TLKAAQKLYP GINYFWVSLQ MNPKTSVLSK ISVEIKAIKV DGNTAPSRQV
     NAKREHYMGV GVRHAGDDGV SAFRIPGLVT TNKGTLLGVY DIRYNNSKDL QEYIEIGVSR
     STDGGQTWEK MRTAIGFGEY DGMPKSQNGI GDPAILVDKQ TGTIWIVAAW THGMGVGAAW
     WNSLQGMTLN QTAQLIMAKS DDDGKTWSAP INITEQVKDP SWYFLLQGPG RGISMEDGTL
     VFASQFIGSD RIPNSSIIYS KDHGKNWHMG SLARPNTTEA QVAEVTPGVL MLNMRDNRGG
     SRAVSTTDDL GKTWKEHVSS RTSLREPVCM ASLISVKAKD NVLGKDILLF SNPDDTKARR
     NITIKASLDG GVTWLPANQV LLDANDGWGY SCLTMIDKET VGILYESSVA HMTFQAVKLK
     DIVRE
//