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E6SHW2

- E6SHW2_THEM7

UniProt

E6SHW2 - E6SHW2_THEM7

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, Tmar_1738
Organism
Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei172 – 1721 By similarityUniRule annotation
Active sitei708 – 7081 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciTMAR644966:GHKT-1777-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Tmar_1738Imported
OrganismiThermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)Imported
Taxonomic identifieri644966 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiales Family XVII. Incertae SedisThermaerobacter
ProteomesiUP000008915: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiWYGAGSA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 3 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 4 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6SHW2-1 [UniParc]FASTAAdd to Basket

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MADSTAVYPS GHGAPEHGEP AYRSRSEEDL YPLLKQEVDL LGRALGEAIR     50
RLSGDRLFEL EEDIRARTKH LRQHPGDEAA RKALRAQVGS LSVTEAEGLI 100
RAFSTYFHLV NLAEERHRVR VNRQRERAST PDHPRPESLL ALVGQLKARG 150
LSYDDVVRLL ASARLVLTFT AHPTETRRRT LRHHLLELNR TLDRLERGEA 200
QLPEVLARVT LLWTTRELRP APPRVEDEVR GGLYYLPTTL WEAVPRLMDA 250
LEQAVAAYYG RRPVLPPPLA FRSWIGGDRD GNPFVTPEVT AWAQGYARAE 300
IARKYAEGLA ALTRDLSVAE ERALLPPLPS LQGAAIALLA GGAGVTQPER 350
ADAAGERGDG PAGGPGAGTA AAPDPGPDAE AGGGHPRAAR TVNGTPGRFL 400
GEPYRQFVYR LQRAWAARTV PEEVWGDGAG AGGGATIAVQ RPFTVETPAT 450
LPGLRHEGEG EGKGRPERPD PLVCPDRAND ANRPDTPARP PRSGPRDESD 500
SAADPGDLAG LLHQVERGLE AAGLGEAAAT LVRPLRWRAQ VFGEAMAPLD 550
VREHAEAHGR AVAELLEAGG VMPAADYLAL DPAAREERLT RELATPRPLA 600
PVGYVPRTRE LAVALGALRA WQGRGAYIIS GCRGPADVLE VFVLAREAGL 650
YRPGQPLPFD VVPLFETLAD LEAAPAAMER LLRNPVFGAH ARARGGCEVM 700
IGYSDSSKDA GYLAANWALY RAQEGITAVA RAAGIPVSFF HGRGTSTARG 750
GGGTAGRAIA SLPPGTVGRR LRLTEQGEAL ADRYAHPELA LRNLEQLLYH 800
FLLAAARDTA VPDQAASDPD ERGPAVRPGS PVAPGHAVAG SDEPSPVAGP 850
GSPAPSALQP ASSGETGGRS SVAPEVPPRG SARSESPVRF EDPRRAQEPL 900
AGGGSAAVPP VWREAMDRAA ARSAEAYRQL LAEPGFFEFF EHFTPIREIA 950
ALKIASRPVA RTGRARRVQD LRAIPWVMAW TQVRLLLPGW YGLAEGLAAV 1000
PRDLRQEMFA RWPFFRSVLD GAALALAKAD LAVAREYLRL VPEPLAGRFF 1050
PRLEQAFLRT RELLEETFGG PLLAHHPVLA RQTALRNPYV DPISYLQVEL 1100
LARYRSAPPD DPQRPALERA LLLSILGIAA GLRNAG 1136
Length:1,136
Mass (Da):122,339
Last modified:March 8, 2011 - v1
Checksum:i3F789C2A41053B2E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002344 Genomic DNA. Translation: ADU51842.1.
RefSeqiWP_013496143.1. NC_014831.1.
YP_004102569.1. NC_014831.1.

Genome annotation databases

EnsemblBacteriaiADU51842; ADU51842; Tmar_1738.
GeneIDi10082121.
KEGGitmr:Tmar_1738.
PATRICi45380768. VBITheMar50867_1790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002344 Genomic DNA. Translation: ADU51842.1 .
RefSeqi WP_013496143.1. NC_014831.1.
YP_004102569.1. NC_014831.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADU51842 ; ADU51842 ; Tmar_1738 .
GeneIDi 10082121.
KEGGi tmr:Tmar_1738.
PATRICi 45380768. VBITheMar50867_1790.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.
OMAi WYGAGSA.

Enzyme and pathway databases

BioCyci TMAR644966:GHKT-1777-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 3 hits.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 4 hits.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a.

Entry informationi

Entry nameiE6SHW2_THEM7
AccessioniPrimary (citable) accession number: E6SHW2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: September 3, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3