Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei172 – 1721UniRule annotation
Active sitei708 – 7081UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTMAR644966:GHKT-1777-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Tmar_1738Imported
OrganismiThermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a)Imported
Taxonomic identifieri644966 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiales Family XVII. Incertae SedisThermaerobacter
ProteomesiUP000008915 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiNYVETQK.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 3 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 4 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6SHW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSTAVYPS GHGAPEHGEP AYRSRSEEDL YPLLKQEVDL LGRALGEAIR
60 70 80 90 100
RLSGDRLFEL EEDIRARTKH LRQHPGDEAA RKALRAQVGS LSVTEAEGLI
110 120 130 140 150
RAFSTYFHLV NLAEERHRVR VNRQRERAST PDHPRPESLL ALVGQLKARG
160 170 180 190 200
LSYDDVVRLL ASARLVLTFT AHPTETRRRT LRHHLLELNR TLDRLERGEA
210 220 230 240 250
QLPEVLARVT LLWTTRELRP APPRVEDEVR GGLYYLPTTL WEAVPRLMDA
260 270 280 290 300
LEQAVAAYYG RRPVLPPPLA FRSWIGGDRD GNPFVTPEVT AWAQGYARAE
310 320 330 340 350
IARKYAEGLA ALTRDLSVAE ERALLPPLPS LQGAAIALLA GGAGVTQPER
360 370 380 390 400
ADAAGERGDG PAGGPGAGTA AAPDPGPDAE AGGGHPRAAR TVNGTPGRFL
410 420 430 440 450
GEPYRQFVYR LQRAWAARTV PEEVWGDGAG AGGGATIAVQ RPFTVETPAT
460 470 480 490 500
LPGLRHEGEG EGKGRPERPD PLVCPDRAND ANRPDTPARP PRSGPRDESD
510 520 530 540 550
SAADPGDLAG LLHQVERGLE AAGLGEAAAT LVRPLRWRAQ VFGEAMAPLD
560 570 580 590 600
VREHAEAHGR AVAELLEAGG VMPAADYLAL DPAAREERLT RELATPRPLA
610 620 630 640 650
PVGYVPRTRE LAVALGALRA WQGRGAYIIS GCRGPADVLE VFVLAREAGL
660 670 680 690 700
YRPGQPLPFD VVPLFETLAD LEAAPAAMER LLRNPVFGAH ARARGGCEVM
710 720 730 740 750
IGYSDSSKDA GYLAANWALY RAQEGITAVA RAAGIPVSFF HGRGTSTARG
760 770 780 790 800
GGGTAGRAIA SLPPGTVGRR LRLTEQGEAL ADRYAHPELA LRNLEQLLYH
810 820 830 840 850
FLLAAARDTA VPDQAASDPD ERGPAVRPGS PVAPGHAVAG SDEPSPVAGP
860 870 880 890 900
GSPAPSALQP ASSGETGGRS SVAPEVPPRG SARSESPVRF EDPRRAQEPL
910 920 930 940 950
AGGGSAAVPP VWREAMDRAA ARSAEAYRQL LAEPGFFEFF EHFTPIREIA
960 970 980 990 1000
ALKIASRPVA RTGRARRVQD LRAIPWVMAW TQVRLLLPGW YGLAEGLAAV
1010 1020 1030 1040 1050
PRDLRQEMFA RWPFFRSVLD GAALALAKAD LAVAREYLRL VPEPLAGRFF
1060 1070 1080 1090 1100
PRLEQAFLRT RELLEETFGG PLLAHHPVLA RQTALRNPYV DPISYLQVEL
1110 1120 1130
LARYRSAPPD DPQRPALERA LLLSILGIAA GLRNAG
Length:1,136
Mass (Da):122,339
Last modified:March 8, 2011 - v1
Checksum:i3F789C2A41053B2E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002344 Genomic DNA. Translation: ADU51842.1.
RefSeqiWP_013496143.1. NC_014831.1.
YP_004102569.1. NC_014831.1.

Genome annotation databases

EnsemblBacteriaiADU51842; ADU51842; Tmar_1738.
KEGGitmr:Tmar_1738.
PATRICi45380768. VBITheMar50867_1790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002344 Genomic DNA. Translation: ADU51842.1.
RefSeqiWP_013496143.1. NC_014831.1.
YP_004102569.1. NC_014831.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiADU51842; ADU51842; Tmar_1738.
KEGGitmr:Tmar_1738.
PATRICi45380768. VBITheMar50867_1790.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiNYVETQK.

Enzyme and pathway databases

BioCyciTMAR644966:GHKT-1777-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 3 hits.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 4 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700841 / DSM 12885 / JCM 10246 / 7p75aImported.

Entry informationi

Entry nameiE6SHW2_THEM7
AccessioniPrimary (citable) accession number: E6SHW2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: April 29, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.