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E6RVR6

- E6RVR6_CAMJS

UniProt

E6RVR6 - E6RVR6_CAMJS

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Protein
Submitted name:

Isocitrate dehydrogenase (NADP) Monomeric isocitrate dehydrogenase (NADP)

Gene
icd, CJS3_0521
Organism
Campylobacter jejuni subsp. jejuni (strain S3)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei142 – 1421Substrate By similarityUniRule annotation
Sitei252 – 2521Critical for catalysis By similarity
Metal bindingi345 – 3451Magnesium or manganese By similarityUniRule annotation
Sitei415 – 4151Critical for catalysis By similarityUniRule annotation
Binding sitei538 – 5381Substrate By similarityUniRule annotation
Metal bindingi539 – 5391Magnesium or manganese By similarityUniRule annotation
Metal bindingi543 – 5431Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCJEJ718271:GLAE-530-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase (NADP) Monomeric isocitrate dehydrogenase (NADP)Imported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
Ordered Locus Names:CJS3_0521Imported
OrganismiCampylobacter jejuni subsp. jejuni (strain S3)Imported
Taxonomic identifieri718271 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
ProteomesiUP000006628: Chromosome

Structurei

3D structure databases

ProteinModelPortaliE6RVR6.
SMRiE6RVR6. Positions 2-731.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni129 – 1368Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

E6RVR6-1 [UniParc]FASTAAdd to Basket

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MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS    50
EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK 100
GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD 150
YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV 200
DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH 250
LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK 300
IENSSKKDEI LKKYNEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA 350
MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG 400
SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY 450
RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL 500
KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL 550
GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA 600
LQASLEFYAN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS 650
HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK 700
VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR 734
Length:734
Mass (Da):82,358
Last modified:March 8, 2011 - v1
Checksum:i0EF7140D92ACFD14
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001960 Genomic DNA. Translation: ADT72278.1.
RefSeqiYP_005659114.1. NC_017281.1.

Genome annotation databases

EnsemblBacteriaiADT72278; ADT72278; CJS3_0521.
GeneIDi12246929.
KEGGicjs:CJS3_0521.
PATRICi45417885. VBICamJej157961_0518.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001960 Genomic DNA. Translation: ADT72278.1 .
RefSeqi YP_005659114.1. NC_017281.1.

3D structure databases

ProteinModelPortali E6RVR6.
SMRi E6RVR6. Positions 2-731.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ADT72278 ; ADT72278 ; CJS3_0521 .
GeneIDi 12246929.
KEGGi cjs:CJS3_0521.
PATRICi 45417885. VBICamJej157961_0518.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci CJEJ718271:GLAE-530-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Campylobacter jejuni strain S3."
    Cooper K.K., Cooper M.A., Zuccolo A., Law B., Joens L.A.
    J. Bacteriol. 193:1491-1492(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S3Imported.

Entry informationi

Entry nameiE6RVR6_CAMJS
AccessioniPrimary (citable) accession number: E6RVR6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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