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E6RVR6

- E6RVR6_CAMJS

UniProt

E6RVR6 - E6RVR6_CAMJS

Protein
Submitted name:

Isocitrate dehydrogenase (NADP) Monomeric isocitrate dehydrogenase (NADP)

Gene

icd

Organism
Campylobacter jejuni subsp. jejuni (strain S3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei142 – 1421SubstrateUniRule annotation
    Sitei252 – 2521Critical for catalysisUniRule annotation
    Metal bindingi345 – 3451Magnesium or manganese
    Sitei415 – 4151Critical for catalysisUniRule annotation
    Binding sitei538 – 5381SubstrateUniRule annotation
    Metal bindingi539 – 5391Magnesium or manganese
    Metal bindingi543 – 5431Magnesium or manganese

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciCJEJ718271:GLAE-530-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase (NADP) Monomeric isocitrate dehydrogenase (NADP)Imported (EC:1.1.1.42Imported)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:CJS3_0521Imported
    OrganismiCampylobacter jejuni subsp. jejuni (strain S3)Imported
    Taxonomic identifieri718271 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
    ProteomesiUP000006628: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliE6RVR6.
    SMRiE6RVR6. Positions 2-731.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni129 – 1368Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    E6RVR6-1 [UniParc]FASTAAdd to Basket

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    MQITYTLTDE SPALATYSFL PIVKAFLSRA HIGVKTSDIS LSGRILATFS    50
    EYLKEEQRCE DALELLGELV KRSDANLIKT PNISASIPQL KAAIKELQDK 100
    GYMLPNYPDE PKNDEELQIK TKYQKVLGSA VNPVLRQGNS DRRSTKAVKD 150
    YAKNNPYRVV EFNPNSKTRV SYMKEGDFFS NEKAVLIDQD CVANIEFTSV 200
    DGKKEILKEG LKLEKNEILD ATFMDVQKLQ EFYAKEIKAS KDDDVLFSLH 250
    LKATMMKVSD PILFGYAVKV FFKELFIEFQ DEFEKLGINP NNGLSELLSK 300
    IENSSKKDEI LKKYNEILAK SADISMVNSD KGITNLHVPS DVIVDASMPA 350
    MLKNGARLWD KEGKEKDTNA VIPDQTYATI YEAVIEDLHK NGTLNPSKLG 400
    SVSNVGLMAK KAQEYGSHDK TFVAKEEGTF KIVSNGKVLL EHKVRKGDIY 450
    RANQAKFDAV LNWIDLGIER SELSGAEAIF WLDSKRASNK IMITLVQNRL 500
    KEKGKNVAIL TPKEACLRSL ELIREGKDVI SITGNVLRDY LTDLFPILEL 550
    GTSAKMLSVV PMLNGGAMFE TGAGGSAPKQ VEQLVEENHL RWDSLGEFLA 600
    LQASLEFYAN KCGNHKAKVL AECLDEAIGE WLENNKAPSR KVKEDDNRTS 650
    HFYLAMYFAN HLARQASDME LQSFFKDIAL ELSSNEEKIR AEFNDAQGVK 700
    VDLGGYYKFD DEKANKIMRP SATFNAILEK IGQR 734
    Length:734
    Mass (Da):82,358
    Last modified:March 8, 2011 - v1
    Checksum:i0EF7140D92ACFD14
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001960 Genomic DNA. Translation: ADT72278.1.
    RefSeqiYP_005659114.1. NC_017281.1.

    Genome annotation databases

    EnsemblBacteriaiADT72278; ADT72278; CJS3_0521.
    GeneIDi12246929.
    KEGGicjs:CJS3_0521.
    PATRICi45417885. VBICamJej157961_0518.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001960 Genomic DNA. Translation: ADT72278.1 .
    RefSeqi YP_005659114.1. NC_017281.1.

    3D structure databases

    ProteinModelPortali E6RVR6.
    SMRi E6RVR6. Positions 2-731.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADT72278 ; ADT72278 ; CJS3_0521 .
    GeneIDi 12246929.
    KEGGi cjs:CJS3_0521.
    PATRICi 45417885. VBICamJej157961_0518.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci CJEJ718271:GLAE-530-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Campylobacter jejuni strain S3."
      Cooper K.K., Cooper M.A., Zuccolo A., Law B., Joens L.A.
      J. Bacteriol. 193:1491-1492(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S3Imported.

    Entry informationi

    Entry nameiE6RVR6_CAMJS
    AccessioniPrimary (citable) accession number: E6RVR6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3