E6RDT0 (E6RDT0_CRYGW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Ordered Locus Names:

CGB_K3320W

Organism

Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus) [Complete proteome] EMBL ADV24969.1

Taxonomic identifier

367775 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Tremellaceae › Filobasidiella › Filobasidiella/Cryptococcus neoformans species complex › Cryptococcus gattii

Protein attributes

Sequence length	1073 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL ADV24969.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E6RDT0 [UniParc]. Last modified March 8, 2011. Version 1. Checksum: C24415B1B5D3DCDD	FASTA	1,073	123,876
	10 20 30 40 50 60 MAVHAPYYHA PPPTQEINGE KPTLTAATTL ERPADCINRG QYPAFYIICG YLNRLRADAP 70 80 90 100 110 120 HKKYELLMRI FGNWREKVGP DLYPLIRLLL PDKDRERPVY NLKESMLARC YIDILSLEKH 130 140 150 160 170 180 SEAAQRLIKW KQPAEGSSNP TGDFAKVCYN EIKARSTVEE GQLSVEAVNM LLDKLAVGKM 190 200 210 220 230 240 KQAEYVPILK AINMQCTAEE QEWIIRIILK DLHISIRERG VLSAFHPDAI DLYNICSDLK 250 260 270 280 290 300 RVCWTLYDPG FRLNKNETHL ELFHSFVPQL CGRMNDTSLE NIAKAIGAPK EFIMEEKLDG 310 320 330 340 350 360 ERIQLHMRGN GAQWFYCSRK AKDYTYLYGA HPGEGSLTRY IANAFQDNVR NIILDGEMMV 370 380 390 400 410 420 WDPVVERYLA FGTLKSAALD HFNDETAPRP CFKVFDILFL NDHCLSRKRL SERKRLLRSG 430 440 450 460 470 480 KIFKNIEDYK GRLEFVDEKR GKSAKDIREY LERVVETKGE GLVVKKTDVI YQTNSRGYDW 490 500 510 520 530 540 IKVKPEYSDQ MGENLEVLVL GGWWGKGGRS GKISRLLCGL REQAFDDGTL QDFLFNRFWN 550 560 570 580 590 600 ELFRLRVDFH KKHWKPFDRS NPPAFMKLGP VGLDDKPDVY IEPENSFVIE VKASEIVPAG 610 620 630 640 650 660 GGYGIGFTLR FPRCKYIYYD RNSRDYELDD DWDFCGTRKL TEWADFMDLF SRPKRSYDDS 670 680 690 700 710 720 QGPGKKKKRK VVRSKKNHIT TNFRGQKLSN IDVETSIFSD MTFYIAKGTS EYPKADLEAL 730 740 750 760 770 780 VHKHGADFTQ AQLSDLSAIV ISPDQKSPLV RAQIRHGVNV IKPEWIFESI ARRKALPLLK 790 800 810 820 830 840 EFLVYASEEA QEGRYYNKTL EQYDKISFVR DRTGETLFEE DGDADVEEEA MDDEDKDEID 850 860 870 880 890 900 MEEAREAKDR RMAREDLKER ESNRSLEQKK LQEAWGLRSR ASTGGSDSEA EEIKSLKEES 910 920 930 940 950 960 DTDSERIRRL RAIYQDEEDE ENDSHESDVG VDGDGYRLVP LNELNDKEEG FMGESPEAMH 970 980 990 1000 1010 1020 YDEDRIFYHL AFYIDTPENA AVNGLESSSP SLNAQERLAK IEKLLVEKGG RAVKSISDPK 1030 1040 1050 1060 1070 LTHIIMDDED SGRYVELTRK TALPKRKHIV TPKWVEDCVD EETLLDEDLY KPR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts." D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G., Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q. , Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D., Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A. MBio 2:E342-E342(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WM276 / ATCC MYA-4071.
[2]	"Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts." D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G., Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q. , Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D., Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A. MBio 0:0-0(2011) Cited for: NUCLEOTIDE SEQUENCE. Strain: WM276.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000296 Genomic DNA. Translation: ADV24969.1.
RefSeq	XP_003196756.1. XM_003196708.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	10185288.
KEGG	cgi:CGB_K3320W.
Phylogenomic databases
KO	K10777.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 2 hits. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E6RDT0_CRYGW

Accession

Primary (citable) accession number: E6RDT0

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	May 1, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)