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E6RDT0

- E6RDT0_CRYGW

UniProt

E6RDT0 - E6RDT0_CRYGW

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Protein

DNA ligase

Gene

CGB_K3320W

Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CGB_K3320WImported
OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
Taxonomic identifieri367775 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
ProteomesiUP000007805: Chromosome K

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 2 hits.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6RDT0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVHAPYYHA PPPTQEINGE KPTLTAATTL ERPADCINRG QYPAFYIICG
60 70 80 90 100
YLNRLRADAP HKKYELLMRI FGNWREKVGP DLYPLIRLLL PDKDRERPVY
110 120 130 140 150
NLKESMLARC YIDILSLEKH SEAAQRLIKW KQPAEGSSNP TGDFAKVCYN
160 170 180 190 200
EIKARSTVEE GQLSVEAVNM LLDKLAVGKM KQAEYVPILK AINMQCTAEE
210 220 230 240 250
QEWIIRIILK DLHISIRERG VLSAFHPDAI DLYNICSDLK RVCWTLYDPG
260 270 280 290 300
FRLNKNETHL ELFHSFVPQL CGRMNDTSLE NIAKAIGAPK EFIMEEKLDG
310 320 330 340 350
ERIQLHMRGN GAQWFYCSRK AKDYTYLYGA HPGEGSLTRY IANAFQDNVR
360 370 380 390 400
NIILDGEMMV WDPVVERYLA FGTLKSAALD HFNDETAPRP CFKVFDILFL
410 420 430 440 450
NDHCLSRKRL SERKRLLRSG KIFKNIEDYK GRLEFVDEKR GKSAKDIREY
460 470 480 490 500
LERVVETKGE GLVVKKTDVI YQTNSRGYDW IKVKPEYSDQ MGENLEVLVL
510 520 530 540 550
GGWWGKGGRS GKISRLLCGL REQAFDDGTL QDFLFNRFWN ELFRLRVDFH
560 570 580 590 600
KKHWKPFDRS NPPAFMKLGP VGLDDKPDVY IEPENSFVIE VKASEIVPAG
610 620 630 640 650
GGYGIGFTLR FPRCKYIYYD RNSRDYELDD DWDFCGTRKL TEWADFMDLF
660 670 680 690 700
SRPKRSYDDS QGPGKKKKRK VVRSKKNHIT TNFRGQKLSN IDVETSIFSD
710 720 730 740 750
MTFYIAKGTS EYPKADLEAL VHKHGADFTQ AQLSDLSAIV ISPDQKSPLV
760 770 780 790 800
RAQIRHGVNV IKPEWIFESI ARRKALPLLK EFLVYASEEA QEGRYYNKTL
810 820 830 840 850
EQYDKISFVR DRTGETLFEE DGDADVEEEA MDDEDKDEID MEEAREAKDR
860 870 880 890 900
RMAREDLKER ESNRSLEQKK LQEAWGLRSR ASTGGSDSEA EEIKSLKEES
910 920 930 940 950
DTDSERIRRL RAIYQDEEDE ENDSHESDVG VDGDGYRLVP LNELNDKEEG
960 970 980 990 1000
FMGESPEAMH YDEDRIFYHL AFYIDTPENA AVNGLESSSP SLNAQERLAK
1010 1020 1030 1040 1050
IEKLLVEKGG RAVKSISDPK LTHIIMDDED SGRYVELTRK TALPKRKHIV
1060 1070
TPKWVEDCVD EETLLDEDLY KPR
Length:1,073
Mass (Da):123,876
Last modified:March 8, 2011 - v1
Checksum:iC24415B1B5D3DCDD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000296 Genomic DNA. Translation: ADV24969.1.
RefSeqiXP_003196756.1. XM_003196708.1.

Genome annotation databases

GeneIDi10185288.
KEGGicgi:CGB_K3320W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000296 Genomic DNA. Translation: ADV24969.1 .
RefSeqi XP_003196756.1. XM_003196708.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 10185288.
KEGGi cgi:CGB_K3320W.

Phylogenomic databases

KOi K10777.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
PANTHERi PTHR10459:SF7. PTHR10459:SF7. 1 hit.
Pfami PF00533. BRCT. 2 hits.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WM276 / ATCC MYA-4071Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WM276.

Entry informationi

Entry nameiE6RDT0_CRYGW
AccessioniPrimary (citable) accession number: E6RDT0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 26, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3