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E6RDT0

- E6RDT0_CRYGW

UniProt

E6RDT0 - E6RDT0_CRYGW

Protein

DNA ligase

Gene

CGB_K3320W

Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:CGB_K3320WImported
    OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
    Taxonomic identifieri367775 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
    ProteomesiUP000007805: Chromosome K

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10777.
    OrthoDBiEOG7QC84G.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    3.40.50.10190. 2 hits.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF00533. BRCT. 2 hits.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00292. BRCT. 2 hits.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 2 hits.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E6RDT0-1 [UniParc]FASTAAdd to Basket

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    MAVHAPYYHA PPPTQEINGE KPTLTAATTL ERPADCINRG QYPAFYIICG     50
    YLNRLRADAP HKKYELLMRI FGNWREKVGP DLYPLIRLLL PDKDRERPVY 100
    NLKESMLARC YIDILSLEKH SEAAQRLIKW KQPAEGSSNP TGDFAKVCYN 150
    EIKARSTVEE GQLSVEAVNM LLDKLAVGKM KQAEYVPILK AINMQCTAEE 200
    QEWIIRIILK DLHISIRERG VLSAFHPDAI DLYNICSDLK RVCWTLYDPG 250
    FRLNKNETHL ELFHSFVPQL CGRMNDTSLE NIAKAIGAPK EFIMEEKLDG 300
    ERIQLHMRGN GAQWFYCSRK AKDYTYLYGA HPGEGSLTRY IANAFQDNVR 350
    NIILDGEMMV WDPVVERYLA FGTLKSAALD HFNDETAPRP CFKVFDILFL 400
    NDHCLSRKRL SERKRLLRSG KIFKNIEDYK GRLEFVDEKR GKSAKDIREY 450
    LERVVETKGE GLVVKKTDVI YQTNSRGYDW IKVKPEYSDQ MGENLEVLVL 500
    GGWWGKGGRS GKISRLLCGL REQAFDDGTL QDFLFNRFWN ELFRLRVDFH 550
    KKHWKPFDRS NPPAFMKLGP VGLDDKPDVY IEPENSFVIE VKASEIVPAG 600
    GGYGIGFTLR FPRCKYIYYD RNSRDYELDD DWDFCGTRKL TEWADFMDLF 650
    SRPKRSYDDS QGPGKKKKRK VVRSKKNHIT TNFRGQKLSN IDVETSIFSD 700
    MTFYIAKGTS EYPKADLEAL VHKHGADFTQ AQLSDLSAIV ISPDQKSPLV 750
    RAQIRHGVNV IKPEWIFESI ARRKALPLLK EFLVYASEEA QEGRYYNKTL 800
    EQYDKISFVR DRTGETLFEE DGDADVEEEA MDDEDKDEID MEEAREAKDR 850
    RMAREDLKER ESNRSLEQKK LQEAWGLRSR ASTGGSDSEA EEIKSLKEES 900
    DTDSERIRRL RAIYQDEEDE ENDSHESDVG VDGDGYRLVP LNELNDKEEG 950
    FMGESPEAMH YDEDRIFYHL AFYIDTPENA AVNGLESSSP SLNAQERLAK 1000
    IEKLLVEKGG RAVKSISDPK LTHIIMDDED SGRYVELTRK TALPKRKHIV 1050
    TPKWVEDCVD EETLLDEDLY KPR 1073
    Length:1,073
    Mass (Da):123,876
    Last modified:March 8, 2011 - v1
    Checksum:iC24415B1B5D3DCDD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000296 Genomic DNA. Translation: ADV24969.1.
    RefSeqiXP_003196756.1. XM_003196708.1.

    Genome annotation databases

    GeneIDi10185288.
    KEGGicgi:CGB_K3320W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000296 Genomic DNA. Translation: ADV24969.1 .
    RefSeqi XP_003196756.1. XM_003196708.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 10185288.
    KEGGi cgi:CGB_K3320W.

    Phylogenomic databases

    KOi K10777.
    OrthoDBi EOG7QC84G.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    3.40.50.10190. 2 hits.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF00533. BRCT. 2 hits.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00292. BRCT. 2 hits.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 2 hits.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WM276 / ATCC MYA-4071Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: WM276.

    Entry informationi

    Entry nameiE6RDT0_CRYGW
    AccessioniPrimary (citable) accession number: E6RDT0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3