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E6RDT0

- E6RDT0_CRYGW

UniProt

E6RDT0 - E6RDT0_CRYGW

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Protein

DNA ligase

Gene
CGB_K3320W
Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CGB_K3320WImported
OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
Taxonomic identifieri367775 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
ProteomesiUP000007805: Chromosome K

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 2 hits.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6RDT0-1 [UniParc]FASTAAdd to Basket

« Hide

MAVHAPYYHA PPPTQEINGE KPTLTAATTL ERPADCINRG QYPAFYIICG     50
YLNRLRADAP HKKYELLMRI FGNWREKVGP DLYPLIRLLL PDKDRERPVY 100
NLKESMLARC YIDILSLEKH SEAAQRLIKW KQPAEGSSNP TGDFAKVCYN 150
EIKARSTVEE GQLSVEAVNM LLDKLAVGKM KQAEYVPILK AINMQCTAEE 200
QEWIIRIILK DLHISIRERG VLSAFHPDAI DLYNICSDLK RVCWTLYDPG 250
FRLNKNETHL ELFHSFVPQL CGRMNDTSLE NIAKAIGAPK EFIMEEKLDG 300
ERIQLHMRGN GAQWFYCSRK AKDYTYLYGA HPGEGSLTRY IANAFQDNVR 350
NIILDGEMMV WDPVVERYLA FGTLKSAALD HFNDETAPRP CFKVFDILFL 400
NDHCLSRKRL SERKRLLRSG KIFKNIEDYK GRLEFVDEKR GKSAKDIREY 450
LERVVETKGE GLVVKKTDVI YQTNSRGYDW IKVKPEYSDQ MGENLEVLVL 500
GGWWGKGGRS GKISRLLCGL REQAFDDGTL QDFLFNRFWN ELFRLRVDFH 550
KKHWKPFDRS NPPAFMKLGP VGLDDKPDVY IEPENSFVIE VKASEIVPAG 600
GGYGIGFTLR FPRCKYIYYD RNSRDYELDD DWDFCGTRKL TEWADFMDLF 650
SRPKRSYDDS QGPGKKKKRK VVRSKKNHIT TNFRGQKLSN IDVETSIFSD 700
MTFYIAKGTS EYPKADLEAL VHKHGADFTQ AQLSDLSAIV ISPDQKSPLV 750
RAQIRHGVNV IKPEWIFESI ARRKALPLLK EFLVYASEEA QEGRYYNKTL 800
EQYDKISFVR DRTGETLFEE DGDADVEEEA MDDEDKDEID MEEAREAKDR 850
RMAREDLKER ESNRSLEQKK LQEAWGLRSR ASTGGSDSEA EEIKSLKEES 900
DTDSERIRRL RAIYQDEEDE ENDSHESDVG VDGDGYRLVP LNELNDKEEG 950
FMGESPEAMH YDEDRIFYHL AFYIDTPENA AVNGLESSSP SLNAQERLAK 1000
IEKLLVEKGG RAVKSISDPK LTHIIMDDED SGRYVELTRK TALPKRKHIV 1050
TPKWVEDCVD EETLLDEDLY KPR 1073
Length:1,073
Mass (Da):123,876
Last modified:March 8, 2011 - v1
Checksum:iC24415B1B5D3DCDD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000296 Genomic DNA. Translation: ADV24969.1.
RefSeqiXP_003196756.1. XM_003196708.1.

Genome annotation databases

GeneIDi10185288.
KEGGicgi:CGB_K3320W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000296 Genomic DNA. Translation: ADV24969.1 .
RefSeqi XP_003196756.1. XM_003196708.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 10185288.
KEGGi cgi:CGB_K3320W.

Phylogenomic databases

KOi K10777.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 2 hits.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WM276 / ATCC MYA-4071.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WM276.

Entry informationi

Entry nameiE6RDT0_CRYGW
AccessioniPrimary (citable) accession number: E6RDT0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: November 13, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi