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Protein

Glutamate decarboxylase

Gene

CGB_J0580C

Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:CGB_J0580CImported
OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
Taxonomic identifieri367775 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
ProteomesiUP000007805 Componenti: Chromosome J

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

E6RCN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSQHVDAD KLIEECKDHP IKRHLAHKAA LYDIPYTSRY EVEDDVPRYS
60 70 80 90 100
MPSKGVNARA TYQLLHDELM LDGNPNMNLA SFVHTWVPDE CNRLIQENIN
110 120 130 140 150
KNLVDQDEYP AAQQIHERCI SMISHLWHAP KEATAMGTAT TGSSEAIMLG
160 170 180 190 200
GLALKRRWQE KMKAAGKDIH NPGPNIIMGA EAQVALEKFA RYFEVEPRLV
210 220 230 240 250
PIKPESSYVM DPKDAIKYVD ENTIGIFVIL GSTYTGAFES VQDMAQELDR
260 270 280 290 300
YEAETGISVP IHVDAASGGF VAPFAYPHYR WDFQIPRVHS INASGHKYGM
310 320 330 340 350
SSVGVGWIIW RSIEYLPKDL IFELHYLGAT DYSFNLNFSR PAHPILAQMF
360 370 380 390 400
TFLNLGFDGY KRIIDKDLTV ARLISRALEH SGYFTCLSQI HHPKALSEIT
410 420 430 440 450
SSAEHSNIVP AIANAANTVL HGKMPTLDDA EYYCEGLPVV SFMFTDEIKK
460 470 480 490 500
KYPNVKQAWI QMQLRSIGWI VPNYPLAPNC ENTEILRVVV RESLSGDLAR
510 520 530 540 550
KLVHDILQVT EDLLNDAGPS YSMSIATRRH ENIDHGKLAG IDAAHIKQRT

TTYAKPC
Length:557
Mass (Da):62,664
Last modified:March 7, 2011 - v1
Checksum:i2DBE9E2AEB6F3E0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000295 Genomic DNA. Translation: ADV24573.1.
RefSeqiXP_003196360.1. XM_003196312.1.

Genome annotation databases

GeneIDi10186755.
KEGGicgi:CGB_J0580C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000295 Genomic DNA. Translation: ADV24573.1.
RefSeqiXP_003196360.1. XM_003196312.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10186755.
KEGGicgi:CGB_J0580C.

Phylogenomic databases

KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: WM276 / ATCC MYA-4071Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: WM276.

Entry informationi

Entry nameiE6RCN4_CRYGW
AccessioniPrimary (citable) accession number: E6RCN4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 7, 2011
Last sequence update: March 7, 2011
Last modified: February 3, 2015
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.