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Protein

DNA ligase

Gene

CGB_H3700W

Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CGB_H3700WImported
OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
Taxonomic identifieri367775 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus gattii species complex
Proteomesi
  • UP000007805 Componenti: Chromosome H

Organism-specific databases

EuPathDBiFungiDB:CGB_H3700W

Interactioni

Protein-protein interaction databases

STRINGi367775.XP_003195763.1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini535 – 672DNA_LIGASE_A3InterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
KOiK10747
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
HAMAPiMF_00407 DNA_ligase, 1 hit
InterProiView protein in InterPro
IPR022865 DNA_ligae_ATP-dep_bac/arc
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

E6RB09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDTDSPVKA NVRKKRTVIL SDDEDEGLSP PVTKKQLSSP RHSHASDEET
60 70 80 90 100
EPPRKIAKTS SKVAPIFAPK EKREKPPSKA SSTSPKAPTK KTEVKNKDEK
110 120 130 140 150
PLASIFTKSV RKPEPKDDDE VSDEVKQKGK DEEEEDEVYD EIEDKQEGEA
160 170 180 190 200
AVKLASIFTK NQKSVPVADK GWKDGEAVPY SALVSTFEKI EATTKRLEIL
210 220 230 240 250
ELLTQFLLVV AKRDTATDTK GSMLLKVVYL CINRLCPDYM GIELGIGESL
260 270 280 290 300
LVKAIAESTG RAMPKIKEDL KKEGDLGKVA TNSRNTQSTM FKPKPLTVPY
310 320 330 340 350
VFQCLTEIAK ATGNASQAKK VGIIKKLLAA CQSTEAKFII RSLEGKLRIG
360 370 380 390 400
LADKTVVVAL AHAIVLKTIG DKKPSPEKLA IMLEQGAETV KAVYSELPSY
410 420 430 440 450
DLVIPALLQD GVEGLRKHCK LTPGVPLKPM LAKPTKAITE VLDRFEGKEF
460 470 480 490 500
TCEYKYDGER AQVHLLEDGT ISVFSRNSEN MSAKYPDLID QIPRALKPTA
510 520 530 540 550
KTFVIDAEAV AYDLETKKIL PFQDLSRRKR KDVKAEDITV RVHIFAFDLL
560 570 580 590 600
YLNGESLLAK ELKERRRLLQ EHFQPVESEF AFAKSSDGST SEEIQAFLEE
610 620 630 640 650
SVKDGCEGLM VKMLTSEAST YEPSRRSMNW LKLKKDYLSG VGDSLDLVVV
660 670 680 690 700
GAYHGKGKRT AVYGAFLLAC YDPDSEHYQT ICKIGTGFSE EILTKFYELL
710 720 730 740 750
KPLELGVVRG DIEVGGAKPD VWFEPRVVWE VLTADLSLSP VYAAAHGVID
760 770 780 790 800
SRGISLRFPR FIRIRDDKSA DEATTAEQVC EFYQRQVSAS GKKGAGPDVD

DFW
Length:803
Mass (Da):89,068
Last modified:March 8, 2011 - v1
Checksum:i9DC8B5A346FAFAAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000293 Genomic DNA Translation: ADV23976.1
RefSeqiXP_003195763.1, XM_003195715.1

Genome annotation databases

EnsemblFungiiADV23976; ADV23976; CGB_H3700W
GeneIDi10185600
KEGGicgi:CGB_H3700W

Similar proteinsi

Entry informationi

Entry nameiE6RB09_CRYGW
AccessioniPrimary (citable) accession number: E6RB09
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: May 23, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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