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Protein

Histone deacetylase

Gene

CGB_D1760C

Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
Ordered Locus Names:CGB_D1760CImported
OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
Taxonomic identifieri367775 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus gattii species complex
Proteomesi
  • UP000007805 Componenti: Chromosome D

Organism-specific databases

EuPathDBiFungiDB:CGB_D1760C.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi367775.XP_003193353.1.

Structurei

3D structure databases

ProteinModelPortaliE6R5L9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 445Hist_deacetylInterPro annotationAdd BLAST415

Phylogenomic databases

eggNOGiKOG1342. Eukaryota.
COG0123. LUCA.
KOiK06067.
OrthoDBiEOG092C386A.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

E6R5L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPDTRFTNR SKIRVSYLWS PSLQRLSDDL PSNVGRSSMV HDLIKSLGLL
60 70 80 90 100
DFEELKGSLS GRGKKGDGDG ESEDDDDNEG DRDEIQNEDK QEADGESQRT
110 120 130 140 150
PVSPTELSTH AQDEKATVVL PDPSLGTKTC LIRYHDRSYI ERLLKAHTDE
160 170 180 190 200
DPNDPTHLPS SPLSSTSSPR RAKIARTDPY NLSHDNPVFP SLSSYISHIA
210 220 230 240 250
AATSTACRLL ATDETDWAVC WDGGRHHAKR KEAGGFCYVN DLVLGGLLLA
260 270 280 290 300
REGRIPLQLK EGEDVKRQRT RAPRIFYLDM DLHYSDGVSA AFHSPTVYPY
310 320 330 340 350
PMEEGVNPPK PPNVLTLSVH HSSPIFFPPP TPLSLLPSPG TESPFSLSIP
360 370 380 390 400
LSAYPSRQTY AKVFNQCIQP IREAWDPDYV ILQLGTDGLP GDRVGQYGNW
410 420 430 440 450
SVAGEGGIKW VVERVKEWGK KVCVTGGGGY RHDNAARAWA EVMGVLLDRD
460 470 480 490 500
FEEDMPIPHH DHFEQYAPSF TLQVPDSHMR DENKPEDLEK AAEVFNVLAE
510
RIKVIVDANS
Length:510
Mass (Da):56,672
Last modified:March 8, 2011 - v1
Checksum:i261498BDA0F45A01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000289 Genomic DNA. Translation: ADV21566.1.
RefSeqiXP_003193353.1. XM_003193305.1.

Genome annotation databases

EnsemblFungiiADV21566; ADV21566; CGB_D1760C.
GeneIDi10191033.
KEGGicgi:CGB_D1760C.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE6R5L9_CRYGW
AccessioniPrimary (citable) accession number: E6R5L9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: June 7, 2017
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported