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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

CGB_C3570W

Organism
Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei146NADUniRule annotation1
Binding sitei171SubstrateUniRule annotation1
Binding sitei204NAD; via amide nitrogenUniRule annotation1
Active sitei255Proton acceptorUniRule annotation1
Binding sitei320NADUniRule annotation1
Binding sitei347NAD; via amide nitrogenUniRule annotation1
Binding sitei349NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi58 – 63NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Ordered Locus Names:CGB_C3570WImported
OrganismiCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)Imported
Taxonomic identifieri367775 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus gattii species complex
Proteomesi
  • UP000007805 Componenti: Chromosome C

Organism-specific databases

EuPathDBiFungiDB:CGB_C3570W

Subcellular locationi

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi367775.XP_003192744.1

Structurei

3D structure databases

ProteinModelPortaliE6R3A5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 222NAD_Gly3P_dh_NInterPro annotationAdd BLAST170
Domaini244 – 390NAD_Gly3P_dh_CInterPro annotationAdd BLAST147

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni320 – 321Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
KOiK00006
OrthoDBiEOG092C3ZQP

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

E6R3A5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAASTAPSS PEVVQQFSDL DIGSTVTTPA VTRPSSPSPP SLPRSPLSSG
60 70 80 90 100
KHKIAIIGSG SWGTALAKIA AENAWRRKDD FHSEVRMWVR EKIVNGKPLT
110 120 130 140 150
HIINKTHLNS RYLPDVVLPR NLVAVPHLKD VVKDATLIVF VVPHQFLHTV
160 170 180 190 200
LNELARPGVL LRGAKAVSAI KGVEVNGTDI QTFASLIEAK VGLPCSALSG
210 220 230 240 250
ANIALEVAMG QFCETTIGCP THDQSLLWHA VFNAPSFRVN TVEDVSGVSL
260 270 280 290 300
AGALKNVVAL AAGMVDGLGL GGNTKAAIMR IGLKEMTGFC LEFFAGSQPE
310 320 330 340 350
TFSNESAGVA DLTVTCFSGR NRKCAEEFVK SGQPFDVIEK KLLNGQKLQG
360 370 380 390
TATAEEVNAF LVARKRAHAY PLFEKVYKIA FEGLPPKNLV VGL
Length:393
Mass (Da):41,910
Last modified:March 8, 2011 - v1
Checksum:iEDE929E2DF60D44B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000288 Genomic DNA Translation: ADV20957.1
RefSeqiXP_003192744.1, XM_003192696.1

Genome annotation databases

EnsemblFungiiADV20957; ADV20957; CGB_C3570W
GeneIDi10187309
KEGGicgi:CGB_C3570W

Similar proteinsi

Entry informationi

Entry nameiE6R3A5_CRYGW
AccessioniPrimary (citable) accession number: E6R3A5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: May 23, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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