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E6NHN2

- E6NHN2_HELPK

UniProt

E6NHN2 - E6NHN2_HELPK

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Protein

Elongation factor Tu

Gene
tuf, HPF30_0188
Organism
Helicobacter pylori (strain F30)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotationImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPYL866345:GLED-198-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotationImported
Ordered Locus Names:HPF30_0188Imported
OrganismiHelicobacter pylori (strain F30)Imported
Taxonomic identifieri866345 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000007936: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PRIDEiE6NHN2.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliE6NHN2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK02358.
OMAiGTEMCMP.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E6NHN2-1 [UniParc]FASTAAdd to Basket

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MAKEKFNRTK PHVNIGTIGH VDHGKTTLSA AISAVLSLKG LAEMKDYDNI    50
DNAPEEKERG ITIATSHIEY ETENRHYAHV DCPGHADYVK NMITGAAQMD 100
GAILVVSAAD GPMPQTREHI LLSRQVGVPH IVVFLNKQDM VDDQELLELV 150
EMEVRELLSA YEFPGDDTPI VAGSALRALE EAKAGNVGEW GEKVLKLMAE 200
VDAYIPTPER DTEKTFLMPV EDVFSIAGRG TVVTGRIERG VVKVGDEVEI 250
VGIRATQKTT VTGVEMFRKE LEKGEAGDNV GVLLRGTKKE EVERGMVLCK 300
PGSITPHKKF EGEIYVLSKE EGGRHTPFFT NYRPQFYVRT TDVTGSITLP 350
EGVEMVMPGD NVKITVELIS PVALELGTKF AIREGGRTVG AGVVSNIIE 399
Length:399
Mass (Da):43,622
Last modified:March 8, 2011 - v1
Checksum:i1D5A3C0F0BDA3B6B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP011941 Genomic DNA. Translation: BAJ56285.1.
RefSeqiYP_005773933.1. NC_017365.1.

Genome annotation databases

EnsemblBacteriaiBAJ56285; BAJ56285; HPF30_0188.
GeneIDi12353531.
KEGGihpf:HPF30_0188.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP011941 Genomic DNA. Translation: BAJ56285.1 .
RefSeqi YP_005773933.1. NC_017365.1.

3D structure databases

ProteinModelPortali E6NHN2.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi E6NHN2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAJ56285 ; BAJ56285 ; HPF30_0188 .
GeneIDi 12353531.
KEGGi hpf:HPF30_0188.

Phylogenomic databases

KOi K02358.
OMAi GTEMCMP.

Enzyme and pathway databases

BioCyci HPYL866345:GLED-198-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS00301. EFACTOR_GTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolution in an oncogenic bacterial species with extreme genome plasticity: Helicobacter pylori East Asian genomes."
    Kawai M., Furuta Y., Yahara K., Tsuru T., Oshima K., Handa N., Takahashi N., Yoshida M., Azuma T., Hattori M., Uchiyama I., Kobayashi I.
    BMC Microbiol. 11:104-104(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F30Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: F30Imported.

Entry informationi

Entry nameiE6NHN2_HELPK
AccessioniPrimary (citable) accession number: E6NHN2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 9, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi