Elongation factor Tu - Neisseria meningitidis serogroup B / serotype 15 (strain H44/76)

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E6MU96 (E6MU96_NEIMH) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 19. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Elongation factor Tu HAMAP-Rule MF_00118
Short name=EF-Tu HAMAP-Rule MF_00118

Gene names

Name:	tuf HAMAP-Rule MF_00118 EMBL EFV64908.1
Ordered Locus Names:	NMBH4476_0121 EMBL ADY94793.1
ORF Names:	NMH_0341 EMBL EFV64908.1

Organism

Neisseria meningitidis serogroup B / serotype 15 (strain H44/76) [Complete proteome] [HAMAP] EMBL EFV64908.1

Taxonomic identifier

909420 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria ›

Protein attributes

Sequence length	394 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325 HAMAP-Rule MF_00118
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00118
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00118.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325 HAMAP-Rule MF_00118

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm HAMAP-Rule MF_00118
Ligand	GTP-binding RuleBase RU000323 HAMAP-Rule MF_00118 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325 HAMAP-Rule MF_00118 EMBL EFV64908.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

19 – 26

GTP By similarity HAMAP-Rule MF_00118

Nucleotide binding

81 – 85

GTP By similarity HAMAP-Rule MF_00118

Nucleotide binding

136 – 139

GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence

Length

Mass (Da)

Tools

E6MU96 [UniParc].

Last modified March 8, 2011. Version 1.
Checksum: 0C571C3D20CBE944
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FASTA

394

42,909

        10         20         30         40         50         60 
MAKEKFERSK PHVNVGTIGH VDHGKTTLTA ALTTILAKKF GGAAKAYDQI DNAPEEKARG 

        70         80         90        100        110        120 
ITINTSHVEY ETETRHYAHV DCPGHADYVK NMITGAAQMD GAILVCSAAD GPMPQTREHI 

       130        140        150        160        170        180 
LLARQVGVPY IIVFMNKCDM VDDAELLELV EMEIRDLLSS YDFPGDDCPI VQGSALKALE 

       190        200        210        220        230        240 
GDAAYEEKIF ELAAALDSYI PTPERAVDKP FLLPIEDVFS ISGRGTVVTG RVERGIIHVG 

       250        260        270        280        290        300 
DEIEIVGLKE TQKTTCTGVE MFRKLLDEGQ AGDNVGVLLR GTKREDVERG QVLAKPGTIT 

       310        320        330        340        350        360 
PHTKFKAEVY VLSKEEGGRH TPFFANYRPQ FYFRTTDVTG AVTLEEGVEM VMPGENVTIT 

       370        380        390 
VELIAPIAME EGLRFAIREG GRTVGAGVVS SVIA

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Hostetler J., Khouri H., Fedorova N., Radune D., Neuendorf B., Ishmael N., Forberger H., Dimitrov G., Szczypinski B., Puiu D., Annavarapu S., Shetty J., Viswanathan L., Busam D., Beeson K., McIntosh T., Daugherty S.C., Durkin A.S. Medini D. Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: H44/76 EMBL ADY94793.1.
[2]	"Genome Sequence of Neisseria meningitidis Serogroup B Strain H44/76." Piet J.R., Huis In 't Veld R.A., van Schaik B.D., van Kampen A.H., Baas F., van de Beek D., Pannekoek Y., van der Ende A. J. Bacteriol. 193:2371-2372(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: H44/76 EMBL EFV64908.1.
[3]	"Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination." Budroni S., Siena E., Dunning Hotopp J., Seib K.L., Serruto D., Nofroni C., Comanducci M., Riley D.R., Daugherty S.C., Angiuoli S., Covacci A., Pizza M., Rappuoli R., Moxon E., Tettelin H., Medini D. Proc. Natl. Acad. Sci. U.S.A. 108:4494-4499(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: H44/76 EMBL ADY94793.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002420 Genomic DNA. Translation: ADY94793.1. AEQZ01000003 Genomic DNA. Translation: EFV64908.1.
RefSeq	YP_005898848.1. NC_017516.1.
3D structure databases
SMR	E6MU96. Positions 2-394.
ModBase	Search...
Proteomic databases
PRIDE	E6MU96.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ADY94793; ADY94793; NMBH4476_0121. EFV64908; EFV64908; NMH_0341.
GeneID	12489279.
KEGG	nmh:NMBH4476_0121.
PATRIC	47148688. VBINeiMen174185_0160.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K02358.
OMA	CEFVGYN.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

E6MU96_NEIMH

Accession

Primary (citable) accession number: E6MU96

Entry history

Integrated into UniProtKB/TrEMBL:	March 8, 2011
Last sequence update:	March 8, 2011
Last modified:	May 1, 2013
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry information