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E5SIA4

- E5SIA4_TRISP

UniProt

E5SIA4 - E5SIA4_TRISP

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Protein
DNA ligase
Gene
Tsp_04168
Organism
Trichinella spiralis (Trichina worm)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:Tsp_04168Imported
OrganismiTrichinella spiralis (Trichina worm)Imported
Taxonomic identifieri6334 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichocephalidaTrichinellidaeTrichinella
ProteomesiUP000006823: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliE5SIA4.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10747.
OMAiMVKMLEG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E5SIA4-1 [UniParc]FASTAAdd to Basket

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MNFGITVLRL FSRKLLFSTA CCKFPNKYSS IMSQASLTSF FAPKGSADSE    50
KRTLSKRKSD LSAVEASNSN PASSVITKDL SKFTEIDEKK RKVQKVDSND 100
DRLENDSVKN ASENAACTSK KGYTILAKEN SYIDPKPNIL FISKSTQLVK 150
LVKNCFSEQE DVVEPQNYKP DATTYDPECN ACWRAGEQVP YLAFAYTMKA 200
IENTSSRLEI IRILSNFFQS VIWLNPDDLL PCIYLCLNRL GPSYEAVELG 250
IAEGTLQKAV AQSTGRSMEK IKADIADKGD LGIVAEMSRN MQRTIFATRP 300
LTVAGIFAKL NQIAHLSGSS SMNKKLEMVK GLLVSCRDCE ARYLIRCLSG 350
KMRIGLAEQS LLVALAHAFA FIERKKENKK KLRDDALKEY LDECALIMKT 400
AECPDYGKIV DIALRHGLHA LPEHCHITPG IPLKPMLAFP SKGIEEVLKR 450
FGSAEFACEW KYDGERAQIH FYDGTVKVFS RNQENHTGKY PDIVELIPKV 500
LSATNNKNNQ TDPISSCIID SEIVAWDTEN QSILPFQVLS TRKRKDAESG 550
DVKVNVSVFA FDLLYLNGQS LTTQPFRERR SMLRSLIEEM DGHFFFTKSL 600
VTNDSDEIGQ FLEEAVKGNC EGLMLKTLDK DATYEIAKRS HKWLKLKKDY 650
LDNTGDTVDL VVIGGYLGVG RRVGVYGGYL LACYNPTTEE YQSICKIGTG 700
FKDEDLQKQA EFFKQHIISA PKSYYRYSSS IAPDHWFDPV QVWEVKAADL 750
SISPKHFAAI GIVDDEKGIS LRFPRFIRVR DDKNPEDATT AEEVAEIYYN 800
QESVKNAKAA ATKDVLSDND VDDDF 825
Length:825
Mass (Da):92,618
Last modified:March 8, 2011 - v1
Checksum:i5519A76F4A5F5F9C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABIR02001012 Genomic DNA. Translation: EFV55486.1.
RefSeqiXP_003374984.1. XM_003374936.1.

Genome annotation databases

EnsemblMetazoaiEFV55486; EFV55486; EFV55486.
GeneIDi10904754.
KEGGitsp:Tsp_04168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ABIR02001012 Genomic DNA. Translation: EFV55486.1 .
RefSeqi XP_003374984.1. XM_003374936.1.

3D structure databases

ProteinModelPortali E5SIA4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai EFV55486 ; EFV55486 ; EFV55486 .
GeneIDi 10904754.
KEGGi tsp:Tsp_04168.

Organism-specific databases

CTDi 10904754.

Phylogenomic databases

KOi K10747.
OMAi MVKMLEG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ISS 195Imported.

Entry informationi

Entry nameiE5SIA4_TRISP
AccessioniPrimary (citable) accession number: E5SIA4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: May 14, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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