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Protein

DNA ligase

Gene

Tsp_04168

Organism
Trichinella spiralis (Trichina worm)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:Tsp_04168Imported
OrganismiTrichinella spiralis (Trichina worm)Imported
Taxonomic identifieri6334 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichinellidaTrichinellidaeTrichinella
Proteomesi
  • UP000006823 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliE5SIA4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini549 – 685DNA_LIGASE_A3InterPro annotationAdd BLAST137

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili86 – 106Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiE5SIA4
KOiK10747
OMAiWIKYKRD
OrthoDBiEOG091G06OS

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

E5SIA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFGITVLRL FSRKLLFSTA CCKFPNKYSS IMSQASLTSF FAPKGSADSE
60 70 80 90 100
KRTLSKRKSD LSAVEASNSN PASSVITKDL SKFTEIDEKK RKVQKVDSND
110 120 130 140 150
DRLENDSVKN ASENAACTSK KGYTILAKEN SYIDPKPNIL FISKSTQLVK
160 170 180 190 200
LVKNCFSEQE DVVEPQNYKP DATTYDPECN ACWRAGEQVP YLAFAYTMKA
210 220 230 240 250
IENTSSRLEI IRILSNFFQS VIWLNPDDLL PCIYLCLNRL GPSYEAVELG
260 270 280 290 300
IAEGTLQKAV AQSTGRSMEK IKADIADKGD LGIVAEMSRN MQRTIFATRP
310 320 330 340 350
LTVAGIFAKL NQIAHLSGSS SMNKKLEMVK GLLVSCRDCE ARYLIRCLSG
360 370 380 390 400
KMRIGLAEQS LLVALAHAFA FIERKKENKK KLRDDALKEY LDECALIMKT
410 420 430 440 450
AECPDYGKIV DIALRHGLHA LPEHCHITPG IPLKPMLAFP SKGIEEVLKR
460 470 480 490 500
FGSAEFACEW KYDGERAQIH FYDGTVKVFS RNQENHTGKY PDIVELIPKV
510 520 530 540 550
LSATNNKNNQ TDPISSCIID SEIVAWDTEN QSILPFQVLS TRKRKDAESG
560 570 580 590 600
DVKVNVSVFA FDLLYLNGQS LTTQPFRERR SMLRSLIEEM DGHFFFTKSL
610 620 630 640 650
VTNDSDEIGQ FLEEAVKGNC EGLMLKTLDK DATYEIAKRS HKWLKLKKDY
660 670 680 690 700
LDNTGDTVDL VVIGGYLGVG RRVGVYGGYL LACYNPTTEE YQSICKIGTG
710 720 730 740 750
FKDEDLQKQA EFFKQHIISA PKSYYRYSSS IAPDHWFDPV QVWEVKAADL
760 770 780 790 800
SISPKHFAAI GIVDDEKGIS LRFPRFIRVR DDKNPEDATT AEEVAEIYYN
810 820
QESVKNAKAA ATKDVLSDND VDDDF
Length:825
Mass (Da):92,618
Last modified:March 8, 2011 - v1
Checksum:i5519A76F4A5F5F9C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABIR02001012 Genomic DNA Translation: EFV55486.1
RefSeqiXP_003374984.1, XM_003374936.1

Genome annotation databases

EnsemblMetazoaiEFV55486; EFV55486; EFV55486
GeneIDi10904754
KEGGitsp:Tsp_04168

Similar proteinsi

Entry informationi

Entry nameiE5SIA4_TRISP
AccessioniPrimary (citable) accession number: E5SIA4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: March 28, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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