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E5SIA4

- E5SIA4_TRISP

UniProt

E5SIA4 - E5SIA4_TRISP

Protein

DNA ligase

Gene

Tsp_04168

Organism
Trichinella spiralis (Trichina worm)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 17 (01 Oct 2014)
      Sequence version 1 (08 Mar 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:Tsp_04168Imported
    OrganismiTrichinella spiralis (Trichina worm)Imported
    Taxonomic identifieri6334 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichocephalidaTrichinellidaeTrichinella
    ProteomesiUP000006823: Unassembled WGS sequence

    Structurei

    3D structure databases

    ProteinModelPortaliE5SIA4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10747.
    OMAiMVKMLEG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E5SIA4-1 [UniParc]FASTAAdd to Basket

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    MNFGITVLRL FSRKLLFSTA CCKFPNKYSS IMSQASLTSF FAPKGSADSE    50
    KRTLSKRKSD LSAVEASNSN PASSVITKDL SKFTEIDEKK RKVQKVDSND 100
    DRLENDSVKN ASENAACTSK KGYTILAKEN SYIDPKPNIL FISKSTQLVK 150
    LVKNCFSEQE DVVEPQNYKP DATTYDPECN ACWRAGEQVP YLAFAYTMKA 200
    IENTSSRLEI IRILSNFFQS VIWLNPDDLL PCIYLCLNRL GPSYEAVELG 250
    IAEGTLQKAV AQSTGRSMEK IKADIADKGD LGIVAEMSRN MQRTIFATRP 300
    LTVAGIFAKL NQIAHLSGSS SMNKKLEMVK GLLVSCRDCE ARYLIRCLSG 350
    KMRIGLAEQS LLVALAHAFA FIERKKENKK KLRDDALKEY LDECALIMKT 400
    AECPDYGKIV DIALRHGLHA LPEHCHITPG IPLKPMLAFP SKGIEEVLKR 450
    FGSAEFACEW KYDGERAQIH FYDGTVKVFS RNQENHTGKY PDIVELIPKV 500
    LSATNNKNNQ TDPISSCIID SEIVAWDTEN QSILPFQVLS TRKRKDAESG 550
    DVKVNVSVFA FDLLYLNGQS LTTQPFRERR SMLRSLIEEM DGHFFFTKSL 600
    VTNDSDEIGQ FLEEAVKGNC EGLMLKTLDK DATYEIAKRS HKWLKLKKDY 650
    LDNTGDTVDL VVIGGYLGVG RRVGVYGGYL LACYNPTTEE YQSICKIGTG 700
    FKDEDLQKQA EFFKQHIISA PKSYYRYSSS IAPDHWFDPV QVWEVKAADL 750
    SISPKHFAAI GIVDDEKGIS LRFPRFIRVR DDKNPEDATT AEEVAEIYYN 800
    QESVKNAKAA ATKDVLSDND VDDDF 825
    Length:825
    Mass (Da):92,618
    Last modified:March 8, 2011 - v1
    Checksum:i5519A76F4A5F5F9C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABIR02001012 Genomic DNA. Translation: EFV55486.1.
    RefSeqiXP_003374984.1. XM_003374936.1.

    Genome annotation databases

    EnsemblMetazoaiEFV55486; EFV55486; EFV55486.
    GeneIDi10904754.
    KEGGitsp:Tsp_04168.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    ABIR02001012 Genomic DNA. Translation: EFV55486.1 .
    RefSeqi XP_003374984.1. XM_003374936.1.

    3D structure databases

    ProteinModelPortali E5SIA4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai EFV55486 ; EFV55486 ; EFV55486 .
    GeneIDi 10904754.
    KEGGi tsp:Tsp_04168.

    Organism-specific databases

    CTDi 10904754.

    Phylogenomic databases

    KOi K10747.
    OMAi MVKMLEG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ISS 195Imported.

    Entry informationi

    Entry nameiE5SIA4_TRISP
    AccessioniPrimary (citable) accession number: E5SIA4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 8, 2011
    Last sequence update: March 8, 2011
    Last modified: October 1, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3