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Protein
Submitted name:

Neuroendocrine convertase 2

Gene

Tsp_03058

Organism
Trichinella spiralis (Trichina worm)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS08.109.

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroendocrine convertase 2Imported
Gene namesi
ORF Names:Tsp_03058Imported
OrganismiTrichinella spiralis (Trichina worm)Imported
Taxonomic identifieri6334 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaEnopleaDorylaimiaTrichocephalidaTrichinellidaeTrichinella
Proteomesi
  • UP000006823 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500319693326 – 610Sequence analysisAdd BLAST585

Structurei

3D structure databases

ProteinModelPortaliE5S2J5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 110S8_pro-domainInterPro annotationAdd BLAST78
Domaini169 – 428Peptidase S8InterPro annotationAdd BLAST260
Domaini539 – 608P_proproteinInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3525. Eukaryota.
COG1404. LUCA.
InParanoidiE5S2J5.
KOiK01360.
OMAiPQRGVLK.
OrthoDBiEOG091G05HI.

Family and domain databases

CDDicd04059. Peptidases_S8_Protein_converta. 1 hit.
Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiView protein in InterPro
IPR008979. Galactose-bd-like.
IPR034182. Kexin/furin.
IPR009020. Peptidase/Inhibitor_I9.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR002884. PrprotnconvertsP.
IPR032815. S8_pro-domain.
PfamiView protein in Pfam
PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF16470. S8_pro-domain. 1 hit.
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 2 hits.
SSF54897. SSF54897. 1 hit.
PROSITEiView protein in PROSITE
PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.

Sequencei

Sequence statusi: Fragment.

E5S2J5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLFFSFQLF LFCAHPPWIA KGAGAGNAFY TNSFHVHLHS GGQEAAHRLA
60 70 80 90 100
KRHGFINVGP VLRSSNEWHF IQPSLPNIRK KRSIFHHRKL ARDPEVRHVV
110 120 130 140 150
QQVGFKRAKR GFRNFEQKSA QSEDLFPPME SPTDPLYPYQ WYLKNTGQWG
160 170 180 190 200
GKPNLDLNVE KAWALGYTGK NVTTAIMDDG VDYMHPDLKD NFNVAASYDF
210 220 230 240 250
SGNDPYPYPR YTDDWFNSHG TRCAGEIAAI RGNGVCGVGV AYNSKIAGIR
260 270 280 290 300
MLDQPYMTDL IEANSMSHEP NLIDIYSASW GPTDDGRTVD GPRNATMRAI
310 320 330 340 350
VKGVNEGRHG LGNIFVWASG DGGEDDDCNC DGYASSMWTI SINSAINNGE
360 370 380 390 400
NAHYDESCSS TLASTFSNGG KNRETGVTTT DLYGQCTKSH SGTSAAAPEA
410 420 430 440 450
AGVFALALEA NPKLTWRDLQ HLTVLTSNRN SLFDGRCREI VDLRIPGVRK
460 470 480 490 500
MHRSSRDNCS HFEWQVNGVG LEFNHLFGFG VLDAAEMVIL AKAWQTVPAR
510 520 530 540 550
FHCDAGSIWE PHRIPSSGTL VLEIDTNACR GTETEVNYLE HVQAVVSLNS
560 570 580 590 600
TRRGDVTLYL ISPAGTQSMI LSRRPKDDDH TDGFTNWPFM TTHTWGEGSS
610
GTWRLVVRFQ
Length:610
Mass (Da):67,822
Last modified:March 8, 2011 - v1
Checksum:i30C70ABB0E8D5284
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei610Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABIR02000309 Genomic DNA. Translation: EFV60966.1.
RefSeqiXP_003379396.1. XM_003379348.1.

Genome annotation databases

EnsemblMetazoaiEFV60966; EFV60966; EFV60966.
GeneIDi10900336.
KEGGitsp:Tsp_03058a.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE5S2J5_TRISP
AccessioniPrimary (citable) accession number: E5S2J5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 8, 2011
Last sequence update: March 8, 2011
Last modified: July 5, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported