IKBKB

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Inhibitor of nuclear factor kappa-B kinase subunit betaImported
Gene namesⁱ	Name:IKBKBImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 8

Organism-specific databases

HGNCⁱ

HGNC:5960. IKBKB.

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000104365.

OpenTargetsⁱ

ENSG00000104365.

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	E5RJH2.
PaxDbⁱ	E5RJH2.
PeptideAtlas More...PeptideAtlasⁱ	E5RJH2.
PRIDEⁱ	E5RJH2.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000104365.
ExpressionAtlasⁱ	E5RJH2. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000430684.

STRINGⁱ

9606.ENSP00000430684.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	E5RJH2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG4250. Eukaryota. ENOG410XRMU. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137876.

Sequenceⁱ

Sequence statusⁱ: Complete.

E5RJH2-1 [UniParc]FASTA Add to basket

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        10         20         30         40 
MSWSPSLTTQ TCGAWEMKER LGTGGFGNVI RWHNQAFKSA AEE

Length:43

Mass (Da):4,801

Last modified:February 8, 2011 - v1

Checksum:ⁱF336670846376C42

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC083973 Genomic DNA. No translation available. KF458748 Genomic DNA. No translation available. KF495673 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC083973 Genomic DNA. No translation available.
KF458748 Genomic DNA. No translation available.
KF495673 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000518679; ENSP00000430557; ENSG00000104365.
UCSC genome browser More...UCSCⁱ	uc064mkk.1. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC083973 Genomic DNA. No translation available. KF458748 Genomic DNA. No translation available. KF495673 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC083973 Genomic DNA. No translation available.
KF458748 Genomic DNA. No translation available.
KF495673 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	E5RJH2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000430684.

STRINGⁱ

9606.ENSP00000430684.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	E5RJH2.
PaxDbⁱ	E5RJH2.
PeptideAtlas More...PeptideAtlasⁱ	E5RJH2.
PRIDEⁱ	E5RJH2.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000518679; ENSP00000430557; ENSG00000104365.
UCSC genome browser More...UCSCⁱ	uc064mkk.1. human.

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:5960. IKBKB.
Open Targets More...OpenTargetsⁱ	ENSG00000104365.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4250. Eukaryota. ENOG410XRMU. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00880000137876.

Miscellaneous databases

ChiTaRSⁱ	IKBKB. human.

ChiTaRSⁱ

IKBKB. human.

Gene expression databases

Bgeeⁱ	ENSG00000104365.
ExpressionAtlasⁱ	E5RJH2. baseline and differential.

Family and domain databases

ProtoNetⁱ	Search...

ProtoNetⁱ

Search...

Entry informationⁱ

Entry nameⁱ	E5RJH2_HUMAN
Accessionⁱ	E5RJH2Primary (citable) accession number: E5RJH2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 8, 2011
	Last sequence update:	February 8, 2011
	Last modified:	June 7, 2017
	This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB - E5RJH2 (E5RJH2_HUMAN)

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Inhibitor of nuclear factor kappa-B kinase subunit beta

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Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Phylogenomic databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

Keywords - Technical termⁱ

Similar proteinsⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - E5RJH2 (E5RJH2_HUMAN)

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Inhibitor of nuclear factor kappa-B kinase subunit beta

IKBKB

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<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ