Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Frizzled-6

Gene

FZD6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation
Biological processWnt signaling pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Frizzled-6Imported
Gene namesi
Name:FZD6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:4044. FZD6.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164930.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi67 ↔ 91PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

MaxQBiE5RJG0.
PaxDbiE5RJG0.
PeptideAtlasiE5RJG0.

Expressioni

Gene expression databases

BgeeiENSG00000164930.
ExpressionAtlasiE5RJG0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE5RJG0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 92FZ (frizzled)InterPro annotationAdd BLAST92

Phylogenomic databases

eggNOGiKOG3577. Eukaryota.
ENOG410XRC8. LUCA.
GeneTreeiENSGT00760000118864.

Family and domain databases

InterProiView protein in InterPro
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF113. PTHR11309:SF113. 1 hit.
PfamiView protein in Pfam
PF01392. Fz. 1 hit.
SMARTiView protein in SMART
SM00063. FRI. 1 hit.
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiView protein in PROSITE
PS50038. FZ. 1 hit.

Sequencei

Sequence statusi: Complete.

E5RJG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMAYNMTFF PNLMGHYDQS IAAVEMEHFL PLANLECSPN IETFLCKAFV
60 70 80 90 100
PTCIEQIHVV PPCRKLCEKV YSDCKKLIDT FGIRWPEELE CDSCRKKMEL
Length:100
Mass (Da):11,654
Last modified:February 8, 2011 - v1
Checksum:i8119E8B13E921E65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025370 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000523933; ENSP00000428257; ENSG00000164930.
UCSCiuc064pil.1. human.

Entry informationi

Entry nameiE5RJG0_HUMAN
AccessioniPrimary (citable) accession number: E5RJG0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: August 30, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported