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E5RJG0

- E5RJG0_HUMAN

UniProt

E5RJG0 - E5RJG0_HUMAN

Protein
Submitted name:

Frizzled-6

Gene

FZD6

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. Wnt-activated receptor activity Source: InterPro

    GO - Biological processi

    1. multicellular organismal development Source: UniProtKB-KW
    2. Wnt signaling pathway Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental proteinSAAS annotation

    Keywords - Biological processi

    Wnt signaling pathwaySAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Frizzled-6Imported
    Gene namesi
    Name:FZD6Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:4044. FZD6.

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiE5RJG0.
    BgeeiE5RJG0.

    Structurei

    3D structure databases

    ProteinModelPortaliE5RJG0.
    SMRiE5RJG0. Positions 3-92.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains FZ (frizzled) domain.SAAS annotation

    Family and domain databases

    Gene3Di1.10.2000.10. 1 hit.
    InterProiIPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026543. FZD6.
    [Graphical view]
    PANTHERiPTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    PfamiPF01392. Fz. 1 hit.
    [Graphical view]
    SMARTiSM00063. FRI. 1 hit.
    [Graphical view]
    SUPFAMiSSF63501. SSF63501. 1 hit.
    PROSITEiPS50038. FZ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E5RJG0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKMAYNMTFF PNLMGHYDQS IAAVEMEHFL PLANLECSPN IETFLCKAFV    50
    PTCIEQIHVV PPCRKLCEKV YSDCKKLIDT FGIRWPEELE CDSCRKKMEL 100
    Length:100
    Mass (Da):11,654
    Last modified:February 8, 2011 - v1
    Checksum:i8119E8B13E921E65
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC025370 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000523933; ENSP00000428257; ENSG00000164930.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC025370 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E5RJG0.
    SMRi E5RJG0. Positions 3-92.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000523933 ; ENSP00000428257 ; ENSG00000164930 .

    Organism-specific databases

    HGNCi HGNC:4044. FZD6.
    GenAtlasi Search...

    Miscellaneous databases

    NextBioi 35498954.

    Gene expression databases

    ArrayExpressi E5RJG0.
    Bgeei E5RJG0.

    Family and domain databases

    Gene3Di 1.10.2000.10. 1 hit.
    InterProi IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026543. FZD6.
    [Graphical view ]
    PANTHERi PTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    Pfami PF01392. Fz. 1 hit.
    [Graphical view ]
    SMARTi SM00063. FRI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF63501. SSF63501. 1 hit.
    PROSITEi PS50038. FZ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 8."
      Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
      , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
      Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiE5RJG0_HUMAN
    AccessioniPrimary (citable) accession number: E5RJG0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 28 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3