ID   E5RJA8_HUMAN            Unreviewed;       186 AA.
AC   E5RJA8;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429146.1};
DE   Flags: Fragment;
GN   Name=CPQ {ECO:0000313|Ensembl:ENSP00000429146.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000429146.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000429146.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000429146.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC010859; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458807; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458810; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E5RJA8; -.
DR   SMR; E5RJA8; -.
DR   MassIVE; E5RJA8; -.
DR   MaxQB; E5RJA8; -.
DR   PeptideAtlas; E5RJA8; -.
DR   ProteomicsDB; 16543; -.
DR   Antibodypedia; 12985; 137 antibodies from 26 providers.
DR   Ensembl; ENST00000517742.1; ENSP00000429146.1; ENSG00000104324.16.
DR   UCSC; uc064out.1; human.
DR   HGNC; HGNC:16910; CPQ.
DR   VEuPathDB; HostDB:ENSG00000104324; -.
DR   GeneTree; ENSGT00390000018110; -.
DR   HOGENOM; CLU_086547_0_0_1; -.
DR   OMA; LFMNEEN; -.
DR   ChiTaRS; CPQ; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000104324; Expressed in left lobe of thyroid gland and 210 other cell types or tissues.
DR   ExpressionAtlas; E5RJA8; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:HPA.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
DR   GO; GO:0070573; F:metallodipeptidase activity; IEA:InterPro.
DR   Gene3D; 3.50.30.30; -; 1.
DR   InterPro; IPR039866; CPQ.
DR   PANTHER; PTHR12053:SF3; CARBOXYPEPTIDASE Q; 1.
DR   PANTHER; PTHR12053; PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:E5RJA8,
KW   ECO:0007829|MaxQB:E5RJA8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..186
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003196831"
FT   NON_TER         186
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000429146.1"
SQ   SEQUENCE   186 AA;  20705 MW;  9C6771923C31F303 CRC64;
     MKFLIFAFFG GVHLLSLCSG KAICKNGISK RTFEEIKEEI ASCGDVAKAI INLAVYGKAQ
     NRSYERLALL VDTVGPRLSG SKNLEKAIQI MYQNLQQDGL EKVHLEPVRI PHWERGEESA
     VMLEPRIHKI AILGLGSSIG TPPEGITAEV LVVTSFDELQ RRASEARGKI VVYNQPYINY
     SRTVQY
//