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Protein
Submitted name:

Matrix metalloproteinase-16

Gene

MMP16

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. metalloendopeptidase activity Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Matrix metalloproteinase-16Imported
Gene namesi
Name:MMP16Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 8

Organism-specific databases

HGNCiHGNC:7162. MMP16.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE5RJA7.
ExpressionAtlasiE5RJA7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE5RJA7.
SMRiE5RJA7. Positions 60-168.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118870.

Family and domain databases

Gene3Di1.10.101.10. 1 hit.
3.40.390.10. 1 hit.
InterProiIPR024079. MetalloPept_cat_dom.
IPR028697. MMP16.
IPR021158. Pept_M10A_Zn_BS.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PANTHERiPTHR10201:SF26. PTHR10201:SF26. 1 hit.
PfamiPF01471. PG_binding_1. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
PROSITEiPS00546. CYSTEINE_SWITCH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E5RJA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDGRYCRRA VLKPGPLSRA GYLRTGRRLD FVHHSGVFFL QTLLWILCAT
60 70 80 90 100
VCGTEQYFNV EVWLQKYGYL PPTDPRMSVL RSAETMQSAL AAMQQFYGIN
110 120 130 140 150
MTGKVDRNTI DWMKKPRCGV PDQTRGSSKF HIRRKRYALT GQKWQHKHIT
160
YSIKNVTPKV GDPETRKA
Length:168
Mass (Da):19,469
Last modified:February 8, 2011 - v1
Checksum:iF023FD5F7A9091C2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei168 – 1681Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC037450 Genomic DNA. No translation available.
AC090575 Genomic DNA. No translation available.
AC090797 Genomic DNA. No translation available.
AC090980 Genomic DNA. No translation available.
KF510324 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000522726; ENSP00000429147; ENSG00000156103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC037450 Genomic DNA. No translation available.
AC090575 Genomic DNA. No translation available.
AC090797 Genomic DNA. No translation available.
AC090980 Genomic DNA. No translation available.
KF510324 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE5RJA7.
SMRiE5RJA7. Positions 60-168.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000522726; ENSP00000429147; ENSG00000156103.

Organism-specific databases

HGNCiHGNC:7162. MMP16.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000118870.

Miscellaneous databases

NextBioi35498908.

Gene expression databases

BgeeiE5RJA7.
ExpressionAtlasiE5RJA7. baseline and differential.

Family and domain databases

Gene3Di1.10.101.10. 1 hit.
3.40.390.10. 1 hit.
InterProiIPR024079. MetalloPept_cat_dom.
IPR028697. MMP16.
IPR021158. Pept_M10A_Zn_BS.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PANTHERiPTHR10201:SF26. PTHR10201:SF26. 1 hit.
PfamiPF01471. PG_binding_1. 1 hit.
[Graphical view]
SUPFAMiSSF47090. SSF47090. 1 hit.
PROSITEiPS00546. CYSTEINE_SWITCH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE5RJA7_HUMAN
AccessioniPrimary (citable) accession number: E5RJA7
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: March 4, 2015
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationPeptideAtlas annotation, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.