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Protein
Submitted name:

Protein-tyrosine kinase 2-beta

Gene

PTK2B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Protein-tyrosine kinase 2-betaImported
Gene namesi
Name:PTK2BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000120899.17.
HGNCiHGNC:9612. PTK2B.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120899.

PTM / Processingi

Proteomic databases

MaxQBiE5RJ77.
PaxDbiE5RJ77.
PeptideAtlasiE5RJ77.
PRIDEiE5RJ77.

Expressioni

Gene expression databases

BgeeiENSG00000120899.
ExpressionAtlasiE5RJ77. baseline and differential.

Structurei

3D structure databases

SMRiE5RJ77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 184FERMInterPro annotationAdd BLAST146

Phylogenomic databases

eggNOGiKOG4257. Eukaryota.
ENOG410ZH9Y. LUCA.
GeneTreeiENSGT00760000118799.

Family and domain databases

CDDicd14473. FERM_B-lobe. 1 hit.
Gene3Di1.20.80.10. 1 hit.
InterProiView protein in InterPro
IPR014352. FERM/acyl-CoA-bd_prot_sf.
IPR035963. FERM_2.
IPR019748. FERM_central.
IPR000299. FERM_domain.
IPR030610. PTK2B.
IPR029071. Ubiquitin-like_domsf.
PANTHERiPTHR24418:SF94. PTHR24418:SF94. 1 hit.
SUPFAMiSSF47031. SSF47031. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiView protein in PROSITE
PS50057. FERM_3. 1 hit.

Sequencei

Sequence statusi: Fragment.

E5RJ77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGVSEPLSR VKLGTLRRPE GPAEPMVVVP VDVEKEDVRI LKVCFYSNSF
60 70 80 90 100
NPGKNFKLVK CTVQTEIREI ITSILLSGRI GPNIRLAECY GLRLKHMKSD
110 120 130 140 150
EIHWLHPQMT VGEVQDKYEC LHVEAEWRYD LQIRYLPEDF MESLKEDRTT
160 170 180
LLYFYQQLRN DYMQRYASKV SEGMALQLGC LELR
Length:184
Mass (Da):21,475
Last modified:February 8, 2011 - v1
Checksum:iDA7E6BD82EA5064D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei184Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010856 Genomic DNA. No translation available.
AC124649 Genomic DNA. No translation available.
AF311103 Genomic DNA. No translation available.
KC877228 Genomic DNA. No translation available.
KF458717 Genomic DNA. No translation available.
KF458718 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000522517; ENSP00000428271; ENSG00000120899.
UCSCiuc064lko.1. human.

Similar proteinsi

Entry informationi

Entry nameiE5RJ77_HUMAN
AccessioniPrimary (citable) accession number: E5RJ77
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 22, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported