ID   E5RJ23_HUMAN            Unreviewed;       136 AA.
AC   E5RJ23;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Regulator of G protein signaling 22 {ECO:0000313|Ensembl:ENSP00000429198.1};
DE   Flags: Fragment;
GN   Name=RGS22 {ECO:0000313|Ensembl:ENSP00000429198.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000429198.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000429198.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000429198.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC021590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP005356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E5RJ23; -.
DR   SMR; E5RJ23; -.
DR   MassIVE; E5RJ23; -.
DR   PeptideAtlas; E5RJ23; -.
DR   ProteomicsDB; 16465; -.
DR   Antibodypedia; 6845; 178 antibodies from 28 providers.
DR   Ensembl; ENST00000520117.5; ENSP00000429198.1; ENSG00000132554.21.
DR   UCSC; uc064ozm.1; human.
DR   HGNC; HGNC:24499; RGS22.
DR   VEuPathDB; HostDB:ENSG00000132554; -.
DR   GeneTree; ENSGT00500000044936; -.
DR   HOGENOM; CLU_1880135_0_0_1; -.
DR   ChiTaRS; RGS22; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000132554; Expressed in sperm and 118 other cell types or tissues.
DR   ExpressionAtlas; E5RJ23; baseline and differential.
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR   InterPro; IPR042651; Rgs22.
DR   PANTHER; PTHR46583; REGULATOR OF G-PROTEIN SIGNALING 22; 1.
DR   PANTHER; PTHR46583:SF1; REGULATOR OF G-PROTEIN SIGNALING 22; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:E5RJ23,
KW   ECO:0007829|ProteomicsDB:E5RJ23};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   NON_TER         136
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000429198.1"
SQ   SEQUENCE   136 AA;  15654 MW;  4D5F1CAD4606EF7B CRC64;
     MILRPPQPCG TEDSLATDDF LVDYFNEFLS LPCLSREEGI KWIKKERLPA FLESDCYFEY
     RLAKLVSQVR WSKSGMNFTV GSNFSPWIVK KPPSLPPPAT EEDNLVIMKK FYVSLGEASY
     TQTKDWFALA KQSQQT
//