E5RIG7 (E5RIG7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Integrin beta RuleBase RU000633

Gene names

Name:

ITGB2 Ensembl ENSP00000428413

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000428413

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	120 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Single-pass type I membrane protein By similarity RuleBase RU000633.
Sequence similarities	Belongs to the integrin beta chain family. RuleBase RU000633
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000428413

Ontologies

Keywords
Biological process	Cell adhesion RuleBase RU000633
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000633
Molecular function	Integrin RuleBase RU000633
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell-matrix adhesion Inferred from electronic annotation. Source: InterPro integrin-mediated signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW multicellular organismal development Inferred from electronic annotation. Source: InterPro
Cellular_component	integrin complex Inferred from electronic annotation. Source: InterPro
Molecular_function	receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	120	1	Ensembl ENSP00000428413

Sequences

	Sequence		Length	Mass (Da)
	E5RIG7 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: 57878F51B9B69EF4	FASTA	120	13,015
	10 20 30 40 50 60 MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKLN FTGPGDPDSI 70 80 90 100 110 120 RCDTRPQLLM RGCAADDIMD PTSLAETQED HNGGQKQLSP QKVTLYLRPG QAAAFNVTFR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of human chromosome 21." Chromosome 21 mapping and sequencing consortium Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A. , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L. Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL773603 Genomic DNA. No translation available. AL844907 Genomic DNA. No translation available. AL844908 Genomic DNA. No translation available.
IPI	IPI00978148.
3D structure databases
ProteinModelPortal	E5RIG7.
SMR	E5RIG7. Positions 23-120.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000517563; ENSP00000428413; ENSG00000160255.
Organism-specific databases
HGNC	HGNC:6155. ITGB2.
GenAtlas	Search...
Gene expression databases
ArrayExpress	E5RIG7.
Bgee	E5RIG7.
Family and domain databases
InterPro	IPR015812. Integrin_bsu. IPR015439. Integrin_bsu-2. IPR002369. Integrin_bsu_N. IPR003659. Plexin-like. IPR016201. Plexin-like_fold. [Graphical view]
PANTHER	PTHR10082. PTHR10082. 1 hit. PTHR10082:SF15. PTHR10082:SF15. 1 hit.
Pfam	PF00362. Integrin_beta. 1 hit. [Graphical view]
PRINTS	PR01186. INTEGRINB.
SMART	SM00423. PSI. 1 hit. [Graphical view]
SUPFAM	SSF103575. Plexin-like_fold. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	ITGB2. human.
NextBio	35498653.

Entry information

Entry name

E5RIG7_HUMAN

Accession

Primary (citable) accession number: E5RIG7

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.