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Protein
Submitted name:

E3 ubiquitin-protein ligase RNF130

Gene

RNF130

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase RNF130Imported
Gene namesi
Name:RNF130Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiHostDB:ENSG00000113269.13
HGNCiHGNC:18280 RNF130

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei195 – 218HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000113269

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500319801128 – 419Sequence analysisAdd BLAST392

Proteomic databases

EPDiE5RI87
MaxQBiE5RI87
PRIDEiE5RI87

Expressioni

Gene expression databases

BgeeiENSG00000113269
ExpressionAtlasiE5RI87 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RI87
SMRiE5RI87
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini264 – 305RING-typeInterPro annotationAdd BLAST42

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0800 Eukaryota
ENOG41121N2 LUCA
GeneTreeiENSGT00760000119057
OMAiKMGHEGT
PhylomeDBiE5RI87

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR003137 PA_domain
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF02225 PA, 1 hit
PF13639 zf-RING_2, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

E5RI87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCAGRAGPA RLAALALLTC SLWPARADNA SQEYYTALIN VTVQEPGRGA
60 70 80 90 100
PLTFRIDRGR YGLDSPKAEV RGQVLAPLPL HGVADHLGCD PQTRFFVPPN
110 120 130 140 150
IKQWIALLQR GNCTFKEKIS RAAFHNAVAV VIYNNKSKEE PVTMTHPGTG
160 170 180 190 200
DIIAVMITEL RGKDILSYLE KNISVQMTIA VGTRMPPKNF SRGSLVFVSI
210 220 230 240 250
SFIVLMIISS AWLIFYFIQK IRYTNARDRN QRRLGDAAKK AISKLTTRTV
260 270 280 290 300
KKGDKETDPD FDHCAVCIES YKQNDVVRIL PCKHVFHKSC VDPWLSEHCT
310 320 330 340 350
CPMCKLNILK ALGIVPNLPC TDNVAFDMER LTRTQAVNRR SALGDLAGDN
360 370 380 390 400
SLGLEPLRTS GISPLPQDGE LTPRTGEINI AVTSGHFFHR NSLSPRSLVY
410
ESEFSTIEPS LDMYDENKT
Length:419
Mass (Da):46,504
Last modified:February 8, 2011 - v1
Checksum:iC763675F65512102
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010285 Genomic DNA No translation available.
AC026413 Genomic DNA No translation available.
AC122713 Genomic DNA No translation available.
RefSeqiXP_011532895.1, XM_011534593.2
UniGeneiHs.484363

Genome annotation databases

EnsembliENST00000522208; ENSP00000429509; ENSG00000113269
GeneIDi55819
UCSCiuc063kss.1 human

Similar proteinsi

Entry informationi

Entry nameiE5RI87_HUMAN
AccessioniPrimary (citable) accession number: E5RI87
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 23, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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