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Protein
Submitted name:

Integrin beta-2

Gene

ITGB2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIntegrinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-2Imported
Gene namesi
Name:ITGB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 21

Organism-specific databases

EuPathDBiHostDB:ENSG00000160255.16.
HGNCiHGNC:6155. ITGB2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000160255.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501096212523 – 49Sequence analysisAdd BLAST27

Proteomic databases

MaxQBiE5RHT0.

Expressioni

Gene expression databases

BgeeiENSG00000160255.
ExpressionAtlasiE5RHT0. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 48PSI_integrinInterPro annotationAdd BLAST26

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1226. Eukaryota.
ENOG410XP60. LUCA.
GeneTreeiENSGT00760000119064.

Family and domain databases

InterProiView protein in InterPro
IPR033760. Integrin_beta_N.
IPR015812. Integrin_bsu.
IPR015439. Integrin_bsu-2.
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF15. PTHR10082:SF15. 1 hit.
PfamiView protein in Pfam
PF17205. PSI_integrin. 1 hit.

Sequencei

Sequence statusi: Fragment.

E5RHT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MLGLRPPLLA LVGLLSLGCV LSQECTKFKV SSCRECIESG PGCTWCQKL
Length:49
Mass (Da):5,269
Last modified:February 8, 2011 - v1
Checksum:iC75444E38FDBB067
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei49Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773603 Genomic DNA. No translation available.
AL844907 Genomic DNA. No translation available.
AL844908 Genomic DNA. No translation available.
KC877928 Genomic DNA. No translation available.
KJ528562 Genomic DNA. Translation: AHZ44414.1.
KJ528563 Genomic DNA. Translation: AHZ44415.1.
KJ528564 Genomic DNA. Translation: AHZ44416.1.
UniGeneiHs.375957.

Genome annotation databases

EnsembliENST00000521995; ENSP00000429683; ENSG00000160255.
UCSCiuc062auo.1. human.

Similar proteinsi

Entry informationi

Entry nameiE5RHT0_HUMAN
AccessioniPrimary (citable) accession number: E5RHT0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: November 22, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported