ID   E5RHM3_HUMAN            Unreviewed;        39 AA.
AC   E5RHM3;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=S-phase kinase associated protein 1 {ECO:0000313|Ensembl:ENSP00000430885.1};
GN   Name=SKP1 {ECO:0000313|Ensembl:ENSP00000430885.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000430885.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000430885.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA   Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA   Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA   Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA   Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA   Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA   Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000430885.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC011336; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC104109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E5RHM3; -.
DR   SMR; E5RHM3; -.
DR   MassIVE; E5RHM3; -.
DR   MaxQB; E5RHM3; -.
DR   PeptideAtlas; E5RHM3; -.
DR   ProteomicsDB; 16027; -.
DR   Ensembl; ENST00000519054.5; ENSP00000430885.1; ENSG00000113558.19.
DR   UCSC; uc063hah.1; human.
DR   HGNC; HGNC:10899; SKP1.
DR   VEuPathDB; HostDB:ENSG00000113558; -.
DR   GeneTree; ENSGT00390000012652; -.
DR   HOGENOM; CLU_3319865_0_0_1; -.
DR   ChiTaRS; SKP1; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   Bgee; ENSG00000113558; Expressed in prefrontal cortex and 211 other cell types or tissues.
DR   ExpressionAtlas; E5RHM3; baseline and differential.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR016073; Skp1_comp_POZ.
DR   Pfam; PF03931; Skp1_POZ; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:E5RHM3,
KW   ECO:0007829|ProteomicsDB:E5RHM3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          2..33
FT                   /note="SKP1 component POZ"
FT                   /evidence="ECO:0000259|Pfam:PF03931"
SQ   SEQUENCE   39 AA;  4321 MW;  AE75ECDE6911F564 CRC64;
     MPSIKLQSSD GEIFEVDVEI AKQSVTIKTM LEGHPFCIV
//