ID   E5RH35_HUMAN            Unreviewed;       130 AA.
AC   E5RH35;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429934.1};
DE   Flags: Fragment;
GN   Name=CPQ {ECO:0000313|Ensembl:ENSP00000429934.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000429934.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000429934.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000429934.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC010859; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003477; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458807; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF458810; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E5RH35; -.
DR   SMR; E5RH35; -.
DR   MassIVE; E5RH35; -.
DR   MaxQB; E5RH35; -.
DR   PeptideAtlas; E5RH35; -.
DR   ProteomicsDB; 15858; -.
DR   Antibodypedia; 12985; 137 antibodies from 26 providers.
DR   Ensembl; ENST00000521142.1; ENSP00000429934.1; ENSG00000104324.16.
DR   UCSC; uc064ouw.1; human.
DR   HGNC; HGNC:16910; CPQ.
DR   VEuPathDB; HostDB:ENSG00000104324; -.
DR   GeneTree; ENSGT00390000018110; -.
DR   OMA; LFMNEEN; -.
DR   ChiTaRS; CPQ; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000104324; Expressed in left lobe of thyroid gland and 210 other cell types or tissues.
DR   ExpressionAtlas; E5RH35; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:HPA.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
DR   GO; GO:0070573; F:metallodipeptidase activity; IEA:InterPro.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR039866; CPQ.
DR   PANTHER; PTHR12053:SF3; CARBOXYPEPTIDASE Q; 1.
DR   PANTHER; PTHR12053; PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:E5RH35,
KW   ECO:0007829|MaxQB:E5RH35};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..130
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003197987"
FT   NON_TER         130
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000429934.1"
SQ   SEQUENCE   130 AA;  14594 MW;  06BE64C544789729 CRC64;
     MKFLIFAFFG GVHLLSLCSG KAICKNGISK RTFEEIKEEI ASCGDVAKAI INLAVYGKAQ
     NRSYERLALL VDTVGPRLSG SKNLEKAIQI MYQNLQQDGL EKVHLEPVRI PHWERGEESA
     VMLEPRIHKI
//