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Protein
Submitted name:

Pleckstrin homology domain-containing family A member 2

Gene

PLEKHA2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Pleckstrin homology domain-containing family A member 2Imported
Gene namesi
Name:PLEKHA2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:14336. PLEKHA2.

Expressioni

Gene expression databases

BgeeiE5RGP3.
ExpressionAtlasiE5RGP3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000393860.

Structurei

3D structure databases

ProteinModelPortaliE5RGP3.
SMRiE5RGP3. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00440000037398.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR011993. PH-like_dom.
IPR001849. PH_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
PROSITEiPS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E5RGP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPYVDRQNRI CGFLDIEEHE NSGKFLRRYF ILDTQANCLL WYMDNPQNLA
60 70 80 90 100
MGAGAVGALQ LTYISKVSIA TPKQKPKTPF CFVINALSQR YFLQANDQKD
110
MKDWVEALNQ ASKIT
Length:115
Mass (Da):13,210
Last modified:February 8, 2011 - v1
Checksum:iB8F7B1F676938E82
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei115 – 1151Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067817 Genomic DNA. No translation available.
AC108863 Genomic DNA. No translation available.
KF495718 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000519640; ENSP00000429956; ENSG00000169499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067817 Genomic DNA. No translation available.
AC108863 Genomic DNA. No translation available.
KF495718 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE5RGP3.
SMRiE5RGP3. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000393860.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000519640; ENSP00000429956; ENSG00000169499.

Organism-specific databases

HGNCiHGNC:14336. PLEKHA2.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00440000037398.

Miscellaneous databases

ChiTaRSiPLEKHA2. human.
NextBioi35498125.

Gene expression databases

BgeeiE5RGP3.
ExpressionAtlasiE5RGP3. baseline and differential.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR011993. PH-like_dom.
IPR001849. PH_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
PROSITEiPS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence and analysis of human chromosome 8."
    Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M., Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S., Asakawa T.
    , Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A., Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III, Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K., Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P., Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H., Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B., O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K., Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L., Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G., Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W., Platzer M., Shimizu N., Lander E.S.
    Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE5RGP3_HUMAN
AccessioniPrimary (citable) accession number: E5RGP3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: July 22, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.