ID   E5RFV6_HUMAN            Unreviewed;        82 AA.
AC   E5RFV6;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=Regulator of G protein signaling 22 {ECO:0000313|Ensembl:ENSP00000427930.1};
DE   Flags: Fragment;
GN   Name=RGS22 {ECO:0000313|Ensembl:ENSP00000427930.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000427930.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000427930.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000427930.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AC021590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP005356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; E5RFV6; -.
DR   MassIVE; E5RFV6; -.
DR   PeptideAtlas; E5RFV6; -.
DR   ProteomicsDB; 15470; -.
DR   Antibodypedia; 6845; 178 antibodies from 28 providers.
DR   Ensembl; ENST00000519408.5; ENSP00000427930.1; ENSG00000132554.21.
DR   UCSC; uc064ozo.1; human.
DR   HGNC; HGNC:24499; RGS22.
DR   VEuPathDB; HostDB:ENSG00000132554; -.
DR   GeneTree; ENSGT00500000044936; -.
DR   OMA; LMRSWYL; -.
DR   ChiTaRS; RGS22; human.
DR   Proteomes; UP000005640; Chromosome 8.
DR   Bgee; ENSG00000132554; Expressed in sperm and 118 other cell types or tissues.
DR   ExpressionAtlas; E5RFV6; baseline and differential.
DR   GO; GO:0001965; F:G-protein alpha-subunit binding; IEA:InterPro.
DR   GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR   InterPro; IPR042651; Rgs22.
DR   PANTHER; PTHR46583; REGULATOR OF G-PROTEIN SIGNALING 22; 1.
DR   PANTHER; PTHR46583:SF1; REGULATOR OF G-PROTEIN SIGNALING 22; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|PeptideAtlas:E5RFV6,
KW   ECO:0007829|ProteomicsDB:E5RFV6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   NON_TER         82
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000427930.1"
SQ   SEQUENCE   82 AA;  9542 MW;  389E658DFE03C227 CRC64;
     MNAPDEDETI NVNYNIMCLS REEGIKWIKK ERLPAFLESD CYFEYRLAKL VSQVRWSKSG
     MNFTVGSNFS PWIVKKPPSL PP
//