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E5RFN6

- E5RFN6_HUMAN

UniProt

E5RFN6 - E5RFN6_HUMAN

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Protein
Submitted name:

ATP-binding cassette sub-family A member 10

Gene
ABCA10
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATPase activity Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family A member 10Imported
Gene namesi
Name:ABCA10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:30. ABCA10.

PTM / Processingi

Proteomic databases

PRIDEiE5RFN6.

Expressioni

Gene expression databases

BgeeiE5RFN6.

Structurei

3D structure databases

ProteinModelPortaliE5RFN6.
SMRiE5RFN6. Positions 396-617, 1192-1307.

Family & Domainsi

Sequence similaritiesi

Belongs to the ABC transporter superfamily.UniRule annotation

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR19229. PTHR19229. 1 hit.
PfamiPF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E5RFN6-1 [UniParc]FASTAAdd to Basket

« Hide

MNKMALASFM KGRTVIGTPD EETMDIELPK KYHEMVGVIF SDTFSYRLKF     50
NWGYRIPVIK EHSEYTEHCW AMHGEIFCYL AKYWLKGFVA FQAAINAAII 100
EVTTNHSVME ELTSVIGINM KIPPFISKGE IMNEWFHFTC LVSFSSFIYF 150
ASLNVARERG KFKKLMTVMG LRESAFWLSW GLTYICFIFI MSIFMALVIT 200
SIPIVFHTGF MVIFTLYSLY GLSLIALAFL MSVLIRKPML AGLAGFLFTV 250
FWGCLGFTVL YRQLPLSLGW VLSLLSPFAF TAGMAQITHL DNYLSGVIFP 300
DPSGDSYKMI ATFFILAFDT LFYLIFTLYF ERVLPDKDGH GDSPLFFLKS 350
SFWSKHQNTH HEIFENEINP EHSSDDSFEP VSPEFHGKEA IRIRNVIKEY 400
NGKTGKVEAL QGIFFDIYEG QITAILGHNG AGKSTLLNIL SGLSVSTEGS 450
ATIYNTQLSE ITDMEEIRKN IGFCPQFNFQ FDFLTVRENL RVFAKIKGIQ 500
PKEVEQEVKR IIMELDMQSI QDIIAKKLSG GQKRKLTLGI AILGDPQVLL 550
LDEPTAGLDP FSRHRVWSLL KEHKVDRLIL FSTQFMDEAD ILADRKVFLS 600
NGKLKCAGSS LFLKRKWGIG YHLSLHRNEM CDTEKITSLI KQHIPDAKLT 650
TESEEKLVYS LPLEKTNKFP DLYSDLDKCS DQGIRNYAVS VTSLNEVFLN 700
LEGKSAIDEP DFDIGKQEKI HVTRNTGDES EMEQVLCSLP ETRKAVSSAA 750
LWRRQIYAVA TLRFLKLRRE RRALLCLLLV LGIAFIPIIL EKIMYKVTRE 800
THCWEFSPSM YFLSLEQIPK TPLTSLLIVN NTGSNIEDLV HSLKCQDIVL 850
EIDDFRNRNG SDDPSYNGAI IVSGDQKDYR FSVACNTKKL NCFPVLMGIV 900
SNALMGIFNF TELIQMESTS FSRDDIVLDL GFIDGSIFLL LITNCVSPFI 950
GMSSISDYKK NVQSQLWISG LWPSAYWCGQ ALVDIPLYFL ILFSIHLIYY 1000
FIFLGFQLSW ELMFVLVVCI IGCAVSLIFL TYVLSFIFRK WRKNNGFWSF 1050
GFFIILICVS TIMVSTQYEK LNLILCMIFI PSFTLLGYVM LLIQLDFMRN 1100
LDSLDNRINE VNKTILLTTL IPYLQSVIFL FVIRCLEMKY GNEIMNKDPV 1150
FRISPRSRET HPNPEEPEEE DEDVQAERVQ AANALTAPNL EEEPVITASC 1200
LHKEYYETKK SCFSTRKKKI AIRNVSFCVK KGEVLGLLGH NGAGKSTSIK 1250
MITGCTKPTA GVVVLQGSRA SVRQQHDNSL KFLGYCPQEN SLWPKLTMKE 1300
HLELYAAVKG LGKEDAALSI SRCALC 1326
Length:1,326
Mass (Da):150,865
Last modified:February 8, 2011 - v1
Checksum:i7521CFBC5605BC55
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005495 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000523419; ENSP00000428032; ENSG00000154263.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005495 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E5RFN6.
SMRi E5RFN6. Positions 396-617, 1192-1307.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi E5RFN6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000523419 ; ENSP00000428032 ; ENSG00000154263 .

Organism-specific databases

HGNCi HGNC:30. ABCA10.
GenAtlasi Search...

Miscellaneous databases

NextBioi 35497801.

Gene expression databases

Bgeei E5RFN6.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR026082. ABC_A.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR19229. PTHR19229. 1 hit.
Pfami PF00005. ABC_tran. 2 hits.
[Graphical view ]
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiE5RFN6_HUMAN
AccessioniPrimary (citable) accession number: E5RFN6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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