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Protein
Submitted name:

ATP-binding cassette sub-family A member 10

Gene

ABCA10

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi427 – 434ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette sub-family A member 10Imported
Gene namesi
Name:ABCA10Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000154263.17
HGNCiHGNC:30 ABCA10

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei135 – 156HelicalSequence analysisAdd BLAST22
Transmembranei176 – 198HelicalSequence analysisAdd BLAST23
Transmembranei210 – 235HelicalSequence analysisAdd BLAST26
Transmembranei241 – 261HelicalSequence analysisAdd BLAST21
Transmembranei268 – 289HelicalSequence analysisAdd BLAST22
Transmembranei309 – 330HelicalSequence analysisAdd BLAST22
Transmembranei773 – 790HelicalSequence analysisAdd BLAST18
Transmembranei893 – 914HelicalSequence analysisAdd BLAST22
Transmembranei926 – 950HelicalSequence analysisAdd BLAST25
Transmembranei985 – 1006HelicalSequence analysisAdd BLAST22
Transmembranei1012 – 1034HelicalSequence analysisAdd BLAST23
Transmembranei1046 – 1065HelicalSequence analysisAdd BLAST20
Transmembranei1071 – 1093HelicalSequence analysisAdd BLAST23
Transmembranei1114 – 1133HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000154263

PTM / Processingi

Proteomic databases

PeptideAtlasiE5RFN6
PRIDEiE5RFN6

Expressioni

Gene expression databases

BgeeiENSG00000154263
ExpressionAtlasiE5RFN6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RFN6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini391 – 626ABC transporterInterPro annotationAdd BLAST236

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0059 Eukaryota
COG1131 LUCA
GeneTreeiENSGT00760000118965

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR026082 ABCA
IPR027417 P-loop_NTPase
PANTHERiPTHR19229 PTHR19229, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

E5RFN6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKMALASFM KGRTVIGTPD EETMDIELPK KYHEMVGVIF SDTFSYRLKF
60 70 80 90 100
NWGYRIPVIK EHSEYTEHCW AMHGEIFCYL AKYWLKGFVA FQAAINAAII
110 120 130 140 150
EVTTNHSVME ELTSVIGINM KIPPFISKGE IMNEWFHFTC LVSFSSFIYF
160 170 180 190 200
ASLNVARERG KFKKLMTVMG LRESAFWLSW GLTYICFIFI MSIFMALVIT
210 220 230 240 250
SIPIVFHTGF MVIFTLYSLY GLSLIALAFL MSVLIRKPML AGLAGFLFTV
260 270 280 290 300
FWGCLGFTVL YRQLPLSLGW VLSLLSPFAF TAGMAQITHL DNYLSGVIFP
310 320 330 340 350
DPSGDSYKMI ATFFILAFDT LFYLIFTLYF ERVLPDKDGH GDSPLFFLKS
360 370 380 390 400
SFWSKHQNTH HEIFENEINP EHSSDDSFEP VSPEFHGKEA IRIRNVIKEY
410 420 430 440 450
NGKTGKVEAL QGIFFDIYEG QITAILGHNG AGKSTLLNIL SGLSVSTEGS
460 470 480 490 500
ATIYNTQLSE ITDMEEIRKN IGFCPQFNFQ FDFLTVRENL RVFAKIKGIQ
510 520 530 540 550
PKEVEQEVKR IIMELDMQSI QDIIAKKLSG GQKRKLTLGI AILGDPQVLL
560 570 580 590 600
LDEPTAGLDP FSRHRVWSLL KEHKVDRLIL FSTQFMDEAD ILADRKVFLS
610 620 630 640 650
NGKLKCAGSS LFLKRKWGIG YHLSLHRNEM CDTEKITSLI KQHIPDAKLT
660 670 680 690 700
TESEEKLVYS LPLEKTNKFP DLYSDLDKCS DQGIRNYAVS VTSLNEVFLN
710 720 730 740 750
LEGKSAIDEP DFDIGKQEKI HVTRNTGDES EMEQVLCSLP ETRKAVSSAA
760 770 780 790 800
LWRRQIYAVA TLRFLKLRRE RRALLCLLLV LGIAFIPIIL EKIMYKVTRE
810 820 830 840 850
THCWEFSPSM YFLSLEQIPK TPLTSLLIVN NTGSNIEDLV HSLKCQDIVL
860 870 880 890 900
EIDDFRNRNG SDDPSYNGAI IVSGDQKDYR FSVACNTKKL NCFPVLMGIV
910 920 930 940 950
SNALMGIFNF TELIQMESTS FSRDDIVLDL GFIDGSIFLL LITNCVSPFI
960 970 980 990 1000
GMSSISDYKK NVQSQLWISG LWPSAYWCGQ ALVDIPLYFL ILFSIHLIYY
1010 1020 1030 1040 1050
FIFLGFQLSW ELMFVLVVCI IGCAVSLIFL TYVLSFIFRK WRKNNGFWSF
1060 1070 1080 1090 1100
GFFIILICVS TIMVSTQYEK LNLILCMIFI PSFTLLGYVM LLIQLDFMRN
1110 1120 1130 1140 1150
LDSLDNRINE VNKTILLTTL IPYLQSVIFL FVIRCLEMKY GNEIMNKDPV
1160 1170 1180 1190 1200
FRISPRSRET HPNPEEPEEE DEDVQAERVQ AANALTAPNL EEEPVITASC
1210 1220 1230 1240 1250
LHKEYYETKK SCFSTRKKKI AIRNVSFCVK KGEVLGLLGH NGAGKSTSIK
1260 1270 1280 1290 1300
MITGCTKPTA GVVVLQGSRA SVRQQHDNSL KFLGYCPQEN SLWPKLTMKE
1310 1320
HLELYAAVKG LGKEDAALSI SRCALC
Length:1,326
Mass (Da):150,865
Last modified:February 8, 2011 - v1
Checksum:i7521CFBC5605BC55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005495 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000523419; ENSP00000428032; ENSG00000154263
UCSCiuc060jhd.1 human

Similar proteinsi

Entry informationi

Entry nameiE5RFN6_HUMAN
AccessioniPrimary (citable) accession number: E5RFN6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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