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Protein
Submitted name:

Bifunctional epoxide hydrolase 2

Gene

EPHX2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional epoxide hydrolase 2Imported
Gene namesi
Name:EPHX2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000120915.13
HGNCiHGNC:3402 EPHX2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120915

PTM / Processingi

Proteomic databases

MaxQBiE5RFH6
PeptideAtlasiE5RFH6
PRIDEiE5RFH6

Expressioni

Gene expression databases

BgeeiENSG00000120915
ExpressionAtlasiE5RFH6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE5RFH6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 348AB hydrolase-1InterPro annotationAdd BLAST273

Phylogenomic databases

eggNOGiKOG3085 Eukaryota
KOG4178 Eukaryota
COG1011 LUCA
GeneTreeiENSGT00530000063213

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
IPR000639 Epox_hydrolase-like
PfamiView protein in Pfam
PF00561 Abhydrolase_1, 1 hit
PRINTSiPR00111 ABHYDROLASE
PR00412 EPOXHYDRLASE
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

E5RFH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLRAAVFDL DGVLALPAVF GVLGRTEEAL ALPRGLLNDA FQKGGPEGAT
60 70 80 90 100
TRLMKGEITL SQPRVRLHFV ELGSGPAVCL CHGFPESWYS WRYQIPALAQ
110 120 130 140 150
AGYRVLAMDM KGYGESSAPP EIEEYCMEVL CKEMVTFLDK LGLSQAVFIG
160 170 180 190 200
HDWGGMLVWY MALFYPERVR AVASLNTPFI PANPNMSPLE SIKANPVFDY
210 220 230 240 250
QLYFQEPGVA EAELEQNLSR TFKSLFRASD ESVLSMHKVC EAGGLFVNSP
260 270 280 290 300
EEPSLSRMVT EEEIQFYVQQ FKKSGFRGPL NWYRNMERNW KWACKSLGRK
310 320 330 340 350
ILIPALMVTA EKDFVLVPQM SQHMEDWIPH LKRGHIEDCG HWTQMDKPTE
360 370
VNQILIKWLD SDARNPPVVS KM
Length:372
Mass (Da):42,103
Last modified:February 8, 2011 - v1
Checksum:i188F4FC9EDE79823
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF311103 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000517536; ENSP00000428875; ENSG00000120915
UCSCiuc064llk.1 human

Similar proteinsi

Entry informationi

Entry nameiE5RFH6_HUMAN
AccessioniPrimary (citable) accession number: E5RFH6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 23, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health