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Protein

Putative dipeptidase MGYG_00085

Gene

MGYG_00085

Organism
Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes a wide range of dipeptides.By similarity

Catalytic activityi

Hydrolysis of dipeptides.PROSITE-ProRule annotation

Cofactori

Zn2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi56Zinc 1; catalyticPROSITE-ProRule annotation1
Metal bindingi58Zinc 1; catalyticPROSITE-ProRule annotation1
Metal bindingi168Zinc 1; catalyticPROSITE-ProRule annotation1
Metal bindingi168Zinc 2; catalyticPROSITE-ProRule annotation1
Binding sitei195SubstratePROSITE-ProRule annotation1
Metal bindingi239Zinc 2; catalyticPROSITE-ProRule annotation1
Metal bindingi260Zinc 2; catalyticPROSITE-ProRule annotation1
Binding sitei271SubstratePROSITE-ProRule annotation1
Binding sitei331SubstratePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionDipeptidase, Hydrolase, Metalloprotease, Protease
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative dipeptidase MGYG_00085 (EC:3.4.13.19)
Gene namesi
ORF Names:MGYG_00085
OrganismiArthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum)
Taxonomic identifieri535722 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeNannizzia
Proteomesi
  • UP000002669 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000041121132 – 425Putative dipeptidase MGYG_00085Add BLAST394

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi107 ↔ 197PROSITE-ProRule annotation
Glycosylationi403N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiE5R2Q7

Interactioni

Protein-protein interaction databases

STRINGi535722.XP_003175993.1

Structurei

3D structure databases

ProteinModelPortaliE5R2Q7
SMRiE5R2Q7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG4127 Eukaryota
COG2355 LUCA
InParanoidiE5R2Q7
OrthoDBiEOG092C2VQR

Family and domain databases

CDDicd01301 rDP_like, 1 hit
InterProiView protein in InterPro
IPR032466 Metal_Hydrolase
IPR008257 Pept_M19
PANTHERiPTHR10443 PTHR10443, 1 hit
PfamiView protein in Pfam
PF01244 Peptidase_M19, 1 hit
SUPFAMiSSF51556 SSF51556, 1 hit
PROSITEiView protein in PROSITE
PS51365 RENAL_DIPEPTIDASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

E5R2Q7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPERRSRLS ETAGLFVSLL ALTSIVPVQA VATVPQTDYA KRAERVLRSA
60 70 80 90 100
PLIDGHNDLP YAIRKSTRDQ IYDGKLPFET SLKGHTDLPR MRKGRMGGQF
110 120 130 140 150
WSVFIACPSD PNAPIDLPTF ATRDTLEQID VARRLVDKYS KDLMFCDNPG
160 170 180 190 200
CAKRAFRQGK IGSFLGIEGG HQVGSSIAAL RQAFYAGARY MTITHNCDNA
210 220 230 240 250
WATAASTVRA GKPDLGMTDF GPALIKEMNR LGMLVDLSHV SHQSMRDILK
260 270 280 290 300
VTKAPVIFSH SSAYEVSKHL RNVPDDVLKT VAKNNGVVMV TFVRTFVNVD
310 320 330 340 350
DPDSVDVNTI VKHIFHIAKV AGWDHVGLGG DYDGTTELPK GLEDVSKYPY
360 370 380 390 400
LIEKVLEAGA TEEQARKLVG ENVLRVWTEV EQIAKKIQRS GALPVEEVWK
410 420
GRNGTALSER STFIEGPAPL AYGCD
Length:425
Mass (Da):46,723
Last modified:February 8, 2011 - v1
Checksum:i8CF4ECF0EF852F64
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS989822 Genomic DNA Translation: EFQ97041.1
RefSeqiXP_003175993.1, XM_003175945.1

Genome annotation databases

EnsemblFungiiEFQ97041; EFQ97041; MGYG_00085
GeneIDi10031304

Similar proteinsi

Entry informationi

Entry nameiDPEP1_ARTGP
AccessioniPrimary (citable) accession number: E5R2Q7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: February 8, 2011
Last modified: May 23, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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