ID   E5KWG9_STRVG            Unreviewed;       302 AA.
AC   E5KWG9;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   28-JUN-2023, entry version 47.
DE   SubName: Full=Prenyltransferase {ECO:0000313|EMBL:ADQ43372.1};
GN   Name=epzP {ECO:0000313|EMBL:ADQ43372.1};
OS   Streptomyces virginiae (Streptomyces cinnamonensis).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1961 {ECO:0000313|EMBL:ADQ43372.1};
RN   [1] {ECO:0000313|EMBL:ADQ43372.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 1042 {ECO:0000313|EMBL:ADQ43372.1};
RX   PubMed=21342470;
RA   Seeger K., Flinspach K., Haug-Schifferdecker E., Kulik A., Gust B.,
RA   Fiedler H.P., Heide L.;
RT   "The biosynthetic genes for prenylated phenazines are located at two
RT   different chromosomal loci of Streptomyces cinnamonensis DSM 1042.";
RL   Microb. Biotechnol. 4:252-262(2011).
RN   [2] {ECO:0007829|PDB:4EE6, ECO:0007829|PDB:4EE7}
RP   X-RAY CRYSTALLOGRAPHY (1.33 ANGSTROMS).
RX   PubMed=23119011; DOI=10.1371/journal.pone.0048427;
RA   Zocher G., Saleh O., Heim J.B., Herbst D.A., Heide L., Stehle T.;
RT   "Structure-based engineering increased the catalytic turnover rate of a
RT   novel phenazine prenyltransferase.";
RL   PLoS ONE 7:e48427-e48427(2012).
CC   -!- SIMILARITY: Belongs to the aromatic prenyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00005368}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HQ228364; ADQ43372.1; -; Genomic_DNA.
DR   PDB; 4EE6; X-ray; 1.33 A; A/B=1-302.
DR   PDB; 4EE7; X-ray; 1.67 A; A/B=1-302.
DR   PDB; 4EE8; X-ray; 1.93 A; A=1-302.
DR   PDBsum; 4EE6; -.
DR   PDBsum; 4EE7; -.
DR   PDBsum; 4EE8; -.
DR   AlphaFoldDB; E5KWG9; -.
DR   SMR; E5KWG9; -.
DR   GO; GO:0004659; F:prenyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR   CDD; cd13931; PT-CloQ_NphB; 1.
DR   InterPro; IPR033964; Aro_prenylTrfase.
DR   InterPro; IPR020965; Prenyltransferase_CloQ.
DR   InterPro; IPR036239; PrenylTrfase-like_sf.
DR   Pfam; PF11468; PTase_Orf2; 1.
DR   SFLD; SFLDS00036; Aromatic_Prenyltransferase; 1.
DR   SFLD; SFLDG01163; II; 1.
DR   SUPFAM; SSF143492; Prenyltransferase-like; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4EE6, ECO:0007829|PDB:4EE7};
KW   Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ADQ43372.1}.
SQ   SEQUENCE   302 AA;  33233 MW;  A82CC764E418CE1D CRC64;
     MSESADLTEL YSIIEKTAQV VDVTASHDKV WPILNAFQDV IADSVISFRA STGSSADDLD
     CRFTMLPKGL DPYARALEHG LTPKTDHPVG SLLKEVHENL PITSCGVDFG VAGGFTKTWS
     FPSAEKLGKV SELVKLPSIP DAVAANRDFF EKWGIADMVS TVGIDYSKRT MNLYFGGGVG
     DRVPAGVFEE KGVRAILGEL GLAAPSEELL KFCERSFVIY VTLSWDSPKI NRFTYSVMTP
     EPLGLPVDLA PTFERLIKSA PYDTEGRNYV YGIASTPKGE YHKIASYYQW QKRVEKLLRS
     DG
//