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E5KWG9

- E5KWG9_STRCM

UniProt

E5KWG9 - E5KWG9_STRCM

Protein
Submitted name:

Prenyltransferase

Gene

epzP

Organism
Streptomyces cinnamonensis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei49 – 491Sulfate 1Imported
    Binding sitei49 – 491Sulfate 2Imported
    Binding sitei55 – 551Sulfate 1Imported
    Binding sitei97 – 971Sulfate 3
    Binding sitei117 – 1171Sulfate 1Imported
    Binding sitei117 – 1171Sulfate 2Imported
    Binding sitei135 – 1351Sulfate 5Imported
    Binding sitei169 – 1691Sulfate 4Imported
    Binding sitei185 – 1851Chloride 3; via amide nitrogenImported
    Binding sitei220 – 2201Chloride 2 (covalent)Imported
    Binding sitei220 – 2201Sulfate 2Imported
    Binding sitei227 – 2271Sulfate 6Imported
    Binding sitei232 – 2321Chloride 1Imported
    Binding sitei232 – 2321Sulfate 7Imported
    Binding sitei236 – 2361Chloride 4Imported
    Binding sitei276 – 2761Sulfate 7Imported
    Binding sitei276 – 2761Sulfate 8
    Binding sitei281 – 2811Sulfate 1Imported
    Binding sitei281 – 2811Sulfate 8
    Binding sitei283 – 2831Sulfate 2Imported
    Binding sitei292 – 2921Sulfate 9; via amide nitrogenImported

    GO - Molecular functioni

    1. transferase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    TransferaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    PrenyltransferaseImported
    Gene namesi
    Name:epzPImported
    OrganismiStreptomyces cinnamonensisImported
    Taxonomic identifieri1900 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4EE6X-ray1.33A/B1-302[»]
    4EE7X-ray1.67A/B1-302[»]
    4EE8X-ray1.93A1-302[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni68 – 692Sulfate 3 binding
    Regioni85 – 862Sulfate 4 bindingImported
    Regioni172 – 1743Sulfate 2 bindingImported

    Family and domain databases

    InterProiIPR020965. Aromatic_prenyltransferase.
    [Graphical view]
    PfamiPF11468. PTase_Orf2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E5KWG9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSESADLTEL YSIIEKTAQV VDVTASHDKV WPILNAFQDV IADSVISFRA    50
    STGSSADDLD CRFTMLPKGL DPYARALEHG LTPKTDHPVG SLLKEVHENL 100
    PITSCGVDFG VAGGFTKTWS FPSAEKLGKV SELVKLPSIP DAVAANRDFF 150
    EKWGIADMVS TVGIDYSKRT MNLYFGGGVG DRVPAGVFEE KGVRAILGEL 200
    GLAAPSEELL KFCERSFVIY VTLSWDSPKI NRFTYSVMTP EPLGLPVDLA 250
    PTFERLIKSA PYDTEGRNYV YGIASTPKGE YHKIASYYQW QKRVEKLLRS 300
    DG 302
    Length:302
    Mass (Da):33,233
    Last modified:February 8, 2011 - v1
    Checksum:iA82CC764E418CE1D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HQ228364 Genomic DNA. Translation: ADQ43372.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HQ228364 Genomic DNA. Translation: ADQ43372.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4EE6 X-ray 1.33 A/B 1-302 [» ]
    4EE7 X-ray 1.67 A/B 1-302 [» ]
    4EE8 X-ray 1.93 A 1-302 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR020965. Aromatic_prenyltransferase.
    [Graphical view ]
    Pfami PF11468. PTase_Orf2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The biosynthetic genes for prenylated phenazines are located at two different chromosomal loci of Streptomyces cinnamonensis DSM 1042."
      Seeger K., Flinspach K., Haug-Schifferdecker E., Kulik A., Gust B., Fiedler H.P., Heide L.
      Microb. Biotechnol. 4:252-262(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: DSM 1042Imported.
    2. "Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase."
      Zocher G., Saleh O., Heim J.B., Herbst D.A., Heide L., Stehle T.
      PLoS ONE 7:e48427-e48427(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.33 ANGSTROMS).

    Entry informationi

    Entry nameiE5KWG9_STRCM
    AccessioniPrimary (citable) accession number: E5KWG9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 8, 2011
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3