Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Mitochondrial DNA polymerase subunit gamma-2

Gene

POLG2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial DNA polymerase subunit gamma-2Imported
Submitted name:
Polymerase (DNA directed), gamma 2, accessory subunitImported
Gene namesi
Name:POLG2Imported
ORF Names:hCG_28169Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000256525.6.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000256525.
ExpressionAtlasiE5KS15. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiE5KS15.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini392 – 477HGTP_anticodonInterPro annotationAdd BLAST86

Phylogenomic databases

eggNOGiKOG2298. Eukaryota.
COG0423. LUCA.
KOiK02333.
OMAiKEMMHIS.
OrthoDBiEOG091G0B28.

Family and domain databases

Gene3Di3.40.50.800. 1 hit.
InterProiView protein in InterPro
IPR004154. Anticodon-bd.
IPR027031. Gly-tRNA_synthase/POLG2.
IPR027030. POLG2.
PANTHERiPTHR10745. PTHR10745. 1 hit.
PTHR10745:SF9. PTHR10745:SF9. 1 hit.
PfamiView protein in Pfam
PF03129. HGTP_anticodon. 1 hit.
SUPFAMiSSF52954. SSF52954. 1 hit.

Sequencei

Sequence statusi: Complete.

E5KS15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSRVAVRAC HKVCRCLLSG FGGRVDAGQP ELLTERSSPK GGHVKSHAEL
60 70 80 90 100
EGNGEHPEAP GSGEGSEALL EICQRRHFLS GSKQQLSRDS LLSGCHPGFG
110 120 130 140 150
PLGVELRKNL AAEWWTSVVV FREQVFPVDA LHHKPGPLLP GDSAFRLVSA
160 170 180 190 200
ETLREILQDK ELSKEQLVAF LENVLKTSGK LRENLLHGAL EHYVNCLDLV
210 220 230 240 250
NKRLPYGLAQ IGVCFHPVFD TKQIRNGVKS IGEKTEASLV WFTPPRTSNQ
260 270 280 290 300
WLDFWLRHRL QWWRKFAMSP SNFSSSDCQD EEGRKGNKLY YNFPWGKELI
310 320 330 340 350
ETLWNLGDHE LLHMYPGNVS KLHGRDGRKN VVPCVLSVNG DLDRGMLAYL
360 370 380 390 400
YDSFQLTENS FTRKKNLHRK VLKLHPCLAP IKVALDVGRG PTLELRQVCQ
410 420 430 440 450
GLFNELLENG ISVWPGYLET MQSSLEQLYS KYDEMSILFT VLVTETTLEN
460 470 480
GLIHLRSRDT TMKEMMHISK LKDFLIKYIS SAKNV
Length:485
Mass (Da):54,911
Last modified:February 8, 2011 - v1
Checksum:iB99734BFEA249192
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ205826 Genomic DNA. Translation: ADP91694.1.
HQ205827 Genomic DNA. Translation: ADP91695.1.
HQ205828 Genomic DNA. Translation: ADP91696.1.
HQ205829 Genomic DNA. Translation: ADP91697.1.
HQ205830 Genomic DNA. Translation: ADP91698.1.
HQ205831 Genomic DNA. Translation: ADP91699.1.
HQ205832 Genomic DNA. Translation: ADP91700.1.
HQ205834 Genomic DNA. Translation: ADP91702.1.
HQ205835 Genomic DNA. Translation: ADP91703.1.
HQ205836 Genomic DNA. Translation: ADP91704.1.
HQ205837 Genomic DNA. Translation: ADP91705.1.
HQ205838 Genomic DNA. Translation: ADP91706.1.
HQ205839 Genomic DNA. Translation: ADP91707.1.
HQ205840 Genomic DNA. Translation: ADP91708.1.
HQ205841 Genomic DNA. Translation: ADP91709.1.
HQ205842 Genomic DNA. Translation: ADP91710.1.
HQ205843 Genomic DNA. Translation: ADP91711.1.
HQ205844 Genomic DNA. Translation: ADP91712.1.
HQ205845 Genomic DNA. Translation: ADP91713.1.
HQ205846 Genomic DNA. Translation: ADP91714.1.
HQ205847 Genomic DNA. Translation: ADP91715.1.
HQ205848 Genomic DNA. Translation: ADP91716.1.
HQ205849 Genomic DNA. Translation: ADP91717.1.
HQ205850 Genomic DNA. Translation: ADP91718.1.
HQ205851 Genomic DNA. Translation: ADP91719.1.
HQ205852 Genomic DNA. Translation: ADP91720.1.
HQ205853 Genomic DNA. Translation: ADP91721.1.
HQ205854 Genomic DNA. Translation: ADP91722.1.
HQ205855 Genomic DNA. Translation: ADP91723.1.
HQ205856 Genomic DNA. Translation: ADP91724.1.
HQ205857 Genomic DNA. Translation: ADP91725.1.
HQ205858 Genomic DNA. Translation: ADP91726.1.
HQ205859 Genomic DNA. Translation: ADP91727.1.
HQ205860 Genomic DNA. Translation: ADP91728.1.
HQ205861 Genomic DNA. Translation: ADP91729.1.
HQ205862 Genomic DNA. Translation: ADP91730.1.
HQ205863 Genomic DNA. Translation: ADP91731.1.
HQ205864 Genomic DNA. Translation: ADP91732.1.
HQ205865 Genomic DNA. Translation: ADP91733.1.
CH471109 Genomic DNA. Translation: EAW94204.1.
RefSeqiNP_009146.2. NM_007215.3.
UniGeneiHs.437009.

Genome annotation databases

GeneIDi11232.
KEGGihsa:11232.

Similar proteinsi

Entry informationi

Entry nameiE5KS15_HUMAN
AccessioniPrimary (citable) accession number: E5KS15
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 27, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.