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Protein
Submitted name:

Mitochondrial DNA polymerase subunit gamma-2

Gene

POLG2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Mitochondrial DNA polymerase subunit gamma-2Imported
Submitted name:
Polymerase (DNA directed), gamma 2, accessory subunitImported
Gene namesi
Name:POLG2Imported
ORF Names:hCG_28169Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSG00000256525.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000442563.

Structurei

3D structure databases

SMRiE5KS15. Positions 67-485.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini392 – 47786HGTP_anticodonInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2298. Eukaryota.
COG0423. LUCA.
KOiK02333.
OMAiLYYNFPW.
OrthoDBiEOG091G0B28.
PhylomeDBiE5KS15.

Family and domain databases

Gene3Di3.40.50.800. 1 hit.
InterProiIPR004154. Anticodon-bd.
IPR027031. Gly-tRNA_synthase/POLG2.
IPR027030. POLG2.
[Graphical view]
PANTHERiPTHR10745. PTHR10745. 1 hit.
PTHR10745:SF8. PTHR10745:SF8. 1 hit.
PfamiPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
SUPFAMiSSF52954. SSF52954. 1 hit.

Sequencei

Sequence statusi: Complete.

E5KS15-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSRVAVRAC HKVCRCLLSG FGGRVDAGQP ELLTERSSPK GGHVKSHAEL
60 70 80 90 100
EGNGEHPEAP GSGEGSEALL EICQRRHFLS GSKQQLSRDS LLSGCHPGFG
110 120 130 140 150
PLGVELRKNL AAEWWTSVVV FREQVFPVDA LHHKPGPLLP GDSAFRLVSA
160 170 180 190 200
ETLREILQDK ELSKEQLVAF LENVLKTSGK LRENLLHGAL EHYVNCLDLV
210 220 230 240 250
NKRLPYGLAQ IGVCFHPVFD TKQIRNGVKS IGEKTEASLV WFTPPRTSNQ
260 270 280 290 300
WLDFWLRHRL QWWRKFAMSP SNFSSSDCQD EEGRKGNKLY YNFPWGKELI
310 320 330 340 350
ETLWNLGDHE LLHMYPGNVS KLHGRDGRKN VVPCVLSVNG DLDRGMLAYL
360 370 380 390 400
YDSFQLTENS FTRKKNLHRK VLKLHPCLAP IKVALDVGRG PTLELRQVCQ
410 420 430 440 450
GLFNELLENG ISVWPGYLET MQSSLEQLYS KYDEMSILFT VLVTETTLEN
460 470 480
GLIHLRSRDT TMKEMMHISK LKDFLIKYIS SAKNV
Length:485
Mass (Da):54,911
Last modified:February 8, 2011 - v1
Checksum:iB99734BFEA249192
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ205826 Genomic DNA. Translation: ADP91694.1.
HQ205827 Genomic DNA. Translation: ADP91695.1.
HQ205828 Genomic DNA. Translation: ADP91696.1.
HQ205829 Genomic DNA. Translation: ADP91697.1.
HQ205830 Genomic DNA. Translation: ADP91698.1.
HQ205831 Genomic DNA. Translation: ADP91699.1.
HQ205832 Genomic DNA. Translation: ADP91700.1.
HQ205834 Genomic DNA. Translation: ADP91702.1.
HQ205835 Genomic DNA. Translation: ADP91703.1.
HQ205836 Genomic DNA. Translation: ADP91704.1.
HQ205837 Genomic DNA. Translation: ADP91705.1.
HQ205838 Genomic DNA. Translation: ADP91706.1.
HQ205839 Genomic DNA. Translation: ADP91707.1.
HQ205840 Genomic DNA. Translation: ADP91708.1.
HQ205841 Genomic DNA. Translation: ADP91709.1.
HQ205842 Genomic DNA. Translation: ADP91710.1.
HQ205843 Genomic DNA. Translation: ADP91711.1.
HQ205844 Genomic DNA. Translation: ADP91712.1.
HQ205845 Genomic DNA. Translation: ADP91713.1.
HQ205846 Genomic DNA. Translation: ADP91714.1.
HQ205847 Genomic DNA. Translation: ADP91715.1.
HQ205848 Genomic DNA. Translation: ADP91716.1.
HQ205849 Genomic DNA. Translation: ADP91717.1.
HQ205850 Genomic DNA. Translation: ADP91718.1.
HQ205851 Genomic DNA. Translation: ADP91719.1.
HQ205852 Genomic DNA. Translation: ADP91720.1.
HQ205853 Genomic DNA. Translation: ADP91721.1.
HQ205854 Genomic DNA. Translation: ADP91722.1.
HQ205855 Genomic DNA. Translation: ADP91723.1.
HQ205856 Genomic DNA. Translation: ADP91724.1.
HQ205857 Genomic DNA. Translation: ADP91725.1.
HQ205858 Genomic DNA. Translation: ADP91726.1.
HQ205859 Genomic DNA. Translation: ADP91727.1.
HQ205860 Genomic DNA. Translation: ADP91728.1.
HQ205861 Genomic DNA. Translation: ADP91729.1.
HQ205862 Genomic DNA. Translation: ADP91730.1.
HQ205863 Genomic DNA. Translation: ADP91731.1.
HQ205864 Genomic DNA. Translation: ADP91732.1.
HQ205865 Genomic DNA. Translation: ADP91733.1.
CH471109 Genomic DNA. Translation: EAW94204.1.
RefSeqiNP_009146.2. NM_007215.3.
UniGeneiHs.437009.

Genome annotation databases

GeneIDi11232.
KEGGihsa:11232.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ205826 Genomic DNA. Translation: ADP91694.1.
HQ205827 Genomic DNA. Translation: ADP91695.1.
HQ205828 Genomic DNA. Translation: ADP91696.1.
HQ205829 Genomic DNA. Translation: ADP91697.1.
HQ205830 Genomic DNA. Translation: ADP91698.1.
HQ205831 Genomic DNA. Translation: ADP91699.1.
HQ205832 Genomic DNA. Translation: ADP91700.1.
HQ205834 Genomic DNA. Translation: ADP91702.1.
HQ205835 Genomic DNA. Translation: ADP91703.1.
HQ205836 Genomic DNA. Translation: ADP91704.1.
HQ205837 Genomic DNA. Translation: ADP91705.1.
HQ205838 Genomic DNA. Translation: ADP91706.1.
HQ205839 Genomic DNA. Translation: ADP91707.1.
HQ205840 Genomic DNA. Translation: ADP91708.1.
HQ205841 Genomic DNA. Translation: ADP91709.1.
HQ205842 Genomic DNA. Translation: ADP91710.1.
HQ205843 Genomic DNA. Translation: ADP91711.1.
HQ205844 Genomic DNA. Translation: ADP91712.1.
HQ205845 Genomic DNA. Translation: ADP91713.1.
HQ205846 Genomic DNA. Translation: ADP91714.1.
HQ205847 Genomic DNA. Translation: ADP91715.1.
HQ205848 Genomic DNA. Translation: ADP91716.1.
HQ205849 Genomic DNA. Translation: ADP91717.1.
HQ205850 Genomic DNA. Translation: ADP91718.1.
HQ205851 Genomic DNA. Translation: ADP91719.1.
HQ205852 Genomic DNA. Translation: ADP91720.1.
HQ205853 Genomic DNA. Translation: ADP91721.1.
HQ205854 Genomic DNA. Translation: ADP91722.1.
HQ205855 Genomic DNA. Translation: ADP91723.1.
HQ205856 Genomic DNA. Translation: ADP91724.1.
HQ205857 Genomic DNA. Translation: ADP91725.1.
HQ205858 Genomic DNA. Translation: ADP91726.1.
HQ205859 Genomic DNA. Translation: ADP91727.1.
HQ205860 Genomic DNA. Translation: ADP91728.1.
HQ205861 Genomic DNA. Translation: ADP91729.1.
HQ205862 Genomic DNA. Translation: ADP91730.1.
HQ205863 Genomic DNA. Translation: ADP91731.1.
HQ205864 Genomic DNA. Translation: ADP91732.1.
HQ205865 Genomic DNA. Translation: ADP91733.1.
CH471109 Genomic DNA. Translation: EAW94204.1.
RefSeqiNP_009146.2. NM_007215.3.
UniGeneiHs.437009.

3D structure databases

SMRiE5KS15. Positions 67-485.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000442563.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11232.
KEGGihsa:11232.

Organism-specific databases

CTDi11232.

Phylogenomic databases

eggNOGiKOG2298. Eukaryota.
COG0423. LUCA.
KOiK02333.
OMAiLYYNFPW.
OrthoDBiEOG091G0B28.
PhylomeDBiE5KS15.

Miscellaneous databases

ChiTaRSiPOLG2. human.
GenomeRNAii11232.

Gene expression databases

BgeeiENSG00000256525.

Family and domain databases

Gene3Di3.40.50.800. 1 hit.
InterProiIPR004154. Anticodon-bd.
IPR027031. Gly-tRNA_synthase/POLG2.
IPR027030. POLG2.
[Graphical view]
PANTHERiPTHR10745. PTHR10745. 1 hit.
PTHR10745:SF8. PTHR10745:SF8. 1 hit.
PfamiPF03129. HGTP_anticodon. 1 hit.
[Graphical view]
SUPFAMiSSF52954. SSF52954. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiE5KS15_HUMAN
AccessioniPrimary (citable) accession number: E5KS15
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: September 7, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.