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Protein
Submitted name:

Myotonin-protein kinase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myotonin-protein kinaseImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000104936.17

Expressioni

Gene expression databases

BgeeiENSG00000104936
ExpressionAtlasiE5KR06 baseline and differential

Structurei

3D structure databases

SMRiE5KR06
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 339Protein kinaseInterPro annotationAdd BLAST269
Domaini340 – 415AGC-kinase C-terminalInterPro annotationAdd BLAST76

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili457 – 530Sequence analysisAdd BLAST74

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IT50 Eukaryota
ENOG410YFQZ LUCA
KOiK08788

Family and domain databases

InterProiView protein in InterPro
IPR000961 AGC-kinase_C
IPR011009 Kinase-like_dom_sf
IPR014930 Myotonic_dystrophy_kinase_coil
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF08826 DMPK_coil, 1 hit
PF00069 Pkinase, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD011252 Myotonic_dystrophy_kinase_coil, 1 hit
SMARTiView protein in SMART
SM00133 S_TK_X, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51285 AGC_KINASE_CTER, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

E5KR06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAEVRLRRL QQLVLDPGFL GLEPLLDLLL GVHQELGASE LAQDKYVADF
60 70 80 90 100
LQWAEPIVVR LKEVRLQRDD FEILKVIGRG AFSEVAVVKM KQTGQVYAMK
110 120 130 140 150
IMNKWDMLKR GEVSCFREER DVLVNGDRRW ITQLHFAFQD ENYLYLVMEY
160 170 180 190 200
YVGGDLLTLL SKFGERIPAE MARFYLAEIV MAIDSVHRLG YVHRDIKPDN
210 220 230 240 250
ILLDRCGHIR LADFGSCLKL RADGTVRSLV AVGTPDYLSP EILQAVGGGP
260 270 280 290 300
GTGSYGPECD WWALGVFAYE MFYGQTPFYA DSTAETYGKI VHYKEHLSLP
310 320 330 340 350
LVDEGVPEEA RDFIQRLLCP PETRLGRGGA GDFRTHPFFF GLDWDGLRDS
360 370 380 390 400
VPPFTPDFEG ATDTCNFDLV EDGLTAMVSG GGETLSDIRE GAPLGVHLPF
410 420 430 440 450
VGYSYSCMAL RDSEVPGPTP MELEAEQLLE PHVQAPSLEP SVSPQDETAE
460 470 480 490 500
VAVPAAVPAA EAEAEVTLRE LQEALEEEVL TRQSLSREME AIRTDNQNFA
510 520 530 540 550
SQLREAEARN RDLEAHVRQL QERMELLQAE GATAVTGVPS PRATDPPSHL
560 570 580 590 600
DGPPAVAVGQ CPLVGPGPMH RRHLLLPARV PRPGLSEALS LLLFAVVLSR
610 620
AAALGCIGLV AHAGQLTAVW RRPGAARAP
Length:629
Mass (Da):69,385
Last modified:February 8, 2011 - v1
Checksum:i46783ED4AE65B493
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ205626 Genomic DNA Translation: ADP91336.1
HQ205627 Genomic DNA Translation: ADP91340.1
HQ205628 Genomic DNA Translation: ADP91344.1
HQ205629 Genomic DNA Translation: ADP91348.1
HQ205630 Genomic DNA Translation: ADP91352.1
HQ205631 Genomic DNA Translation: ADP91356.1
HQ205632 Genomic DNA Translation: ADP91360.1
HQ205633 Genomic DNA Translation: ADP91364.1
HQ205634 Genomic DNA Translation: ADP91368.1
HQ205635 Genomic DNA Translation: ADP91372.1
HQ205636 Genomic DNA Translation: ADP91376.1
HQ205637 Genomic DNA Translation: ADP91380.1
HQ205638 Genomic DNA Translation: ADP91384.1
HQ205639 Genomic DNA Translation: ADP91388.1
HQ205640 Genomic DNA Translation: ADP91392.1
HQ205641 Genomic DNA Translation: ADP91396.1
HQ205642 Genomic DNA Translation: ADP91400.1
HQ205643 Genomic DNA Translation: ADP91404.1
HQ205644 Genomic DNA Translation: ADP91408.1
HQ205645 Genomic DNA Translation: ADP91412.1
HQ205646 Genomic DNA Translation: ADP91416.1
HQ205647 Genomic DNA Translation: ADP91420.1
HQ205648 Genomic DNA Translation: ADP91424.1
HQ205649 Genomic DNA Translation: ADP91428.1
HQ205650 Genomic DNA Translation: ADP91432.1
HQ205651 Genomic DNA Translation: ADP91436.1
HQ205652 Genomic DNA Translation: ADP91440.1
HQ205653 Genomic DNA Translation: ADP91444.1
HQ205654 Genomic DNA Translation: ADP91448.1
HQ205655 Genomic DNA Translation: ADP91452.1
HQ205656 Genomic DNA Translation: ADP91456.1
HQ205657 Genomic DNA Translation: ADP91460.1
HQ205658 Genomic DNA Translation: ADP91464.1
HQ205659 Genomic DNA Translation: ADP91468.1
HQ205660 Genomic DNA Translation: ADP91472.1
HQ205661 Genomic DNA Translation: ADP91476.1
HQ205662 Genomic DNA Translation: ADP91480.1
HQ205663 Genomic DNA Translation: ADP91484.1
HQ205664 Genomic DNA Translation: ADP91488.1
HQ205665 Genomic DNA Translation: ADP91492.1
RefSeqiNP_004400.4, NM_004409.4
UniGeneiHs.631596

Genome annotation databases

GeneIDi1760
KEGGihsa:1760

Entry informationi

Entry nameiE5KR06_HUMAN
AccessioniPrimary (citable) accession number: E5KR06
Entry historyiIntegrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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