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Protein
Submitted name:

Leucine-rich PPR-motif containing

Gene

LRPPRC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Leucine-rich PPR-motif containingImported
Submitted name:
Mitochondrial leucine-rich PPR motif-containing proteinImported
Gene namesi
Name:LRPPRCImported
ORF Names:hCG_16810Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000260665.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini222 – 329108PPR_longInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG4318. Eukaryota.
ENOG410XSG9. LUCA.
KOiK17964.
OMAiPIRQHYF.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
InterProiIPR002885. Pentatricopeptide_repeat.
IPR033443. PPR_long.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01535. PPR. 3 hits.
PF13812. PPR_3. 1 hit.
PF17177. PPR_long. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00756. PPR. 2 hits.
PROSITEiPS51375. PPR. 11 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E5KNY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAALLRSARW LLRAGAAPRL PLSLRLLPGG PGRLHAASYL PAARAGPVAG
60 70 80 90 100
GLLSPARLYA IAAKEKDIQE ESTFSSRKIS NQFDWALMRL DLSVRRTGRI
110 120 130 140 150
PKKLLQKVFN DTCRSGGLGG SHALLLLRSC GSLLPELKLE ERTEFAHRIW
160 170 180 190 200
DTLQKLGAVY DVSHYNALLK VYLQNEYKFS PTDFLAKMEE ANIQPNRVTY
210 220 230 240 250
QRLIASYCNV GDIEGASKIL GFMKTKDLPV TEAVFSALVT GHARAGDMEN
260 270 280 290 300
AENILTVMRD AGIEPGPDTY LALLNAYAEK GDIDHVKQTL EKVEKSELHL
310 320 330 340 350
MDRDLLQIIF SFSKAGYPQY VSEILEKVTC ERRYIPDAMN LILLLVTEKL
360 370 380 390 400
EDVALQILLA CPVSKEDGPS VFGSFFLQHC VTMNTPVEKL TDYCKKLKEV
410 420 430 440 450
QMHSFPLQFT LHCALLANKT DLAKALMKAV KEEGFPIRPH YFWPLLVGRR
460 470 480 490 500
KEKNVQGIIE ILKGMQELGV HPDQETYTDY VIPCFDSVNS ARAILQENGC
510 520 530 540 550
LSDSDMFSQA GLRSEAANGN LDFVLSFLKS NTLPISLQSI RSSLLLGFRR
560 570 580 590 600
SMNINLWSEI TELLYKDGRY CQEPRGPTEA VGYFLYNLID SMSDSEVQAK
610 620 630 640 650
EEHLRQYFHQ LEKMNVKIPE NIYRGIRNLL ESYHVPELIK DAHLLVESKN
660 670 680 690 700
LDFQKTVQLT SSELESTLET LKAENQPIRD VLKQLILVLC SEENMQKALE
710 720 730 740 750
LKAKYESDMV TGGYAALINL CCRHDKVEDA LNLKEEFDRL DSSAVLDTGK
760 770 780 790 800
YVGLVRVLAK HGKLQDAINI LKEMKEKDVL IKDTTALSFF HMLNGAALRG
810 820 830 840 850
EIETVKQLHE AIVTLGLAEP STNISFPLVT VHLEKGDLST ALEVAIDCYE
860 870 880 890 900
KYKVLPRIHD VLCKLVEKGE TDLIQKAMDF VSQEQGEMVM LYDLFFAFLQ
910 920 930 940 950
TGNYKEAKKI IETPGIRARS ARLQWFCDRC VANNQVETLE KLVELTQKLF
960 970 980 990 1000
ECDRDQMYYN LLKLYKINGD WQRADAVWNK IQEENVIPRE KTLRLLAEIL
1010 1020 1030 1040 1050
REGNQEVPFD VPELWYEDEK HSLNSSSAST TEPDFQKDIL IACRLNQKKG
1060 1070 1080 1090 1100
AYDIFLNAKE QNIVFNAETY SNLIKLLMSE DYFTQAMEVK AFAETHIKGF
1110 1120 1130 1140 1150
TLNDAANSRL IITQVRRDYL KEAVTTLKTV LDQQQTPSRL AVTRVIQALA
1160 1170 1180 1190 1200
MKGDVENIEV VQKMLNGLED SIGLSKMVFI NNIALAQIKN NNIDAAIENI
1210 1220 1230 1240 1250
ENMLTSENKV IEPQYFGLAY LFRKVIEEQL EPAVEKISIM AERLANQFAI
1260 1270 1280 1290 1300
YKPVTDFFLQ LVDAGKVDDA RALLQRCGAI AEQTPILLLF LLRNSRKQGK
1310 1320 1330 1340 1350
ASTVKSVLEL IPELNEKEEA YNSLMKSYVS EKDVTSAKAL YEHLTAKNTK
1360 1370 1380 1390
LDDLFLKRYA SLLKYAGEPV PFIEPPESFE FYAQQLRKLR ENSS
Length:1,394
Mass (Da):157,905
Last modified:February 8, 2011 - v1
Checksum:i61AB0C8BF8A972E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ205426 Genomic DNA. Translation: ADP90894.1.
HQ205427 Genomic DNA. Translation: ADP90895.1.
HQ205428 Genomic DNA. Translation: ADP90896.1.
HQ205429 Genomic DNA. Translation: ADP90897.1.
HQ205430 Genomic DNA. Translation: ADP90898.1.
HQ205431 Genomic DNA. Translation: ADP90899.1.
HQ205432 Genomic DNA. Translation: ADP90900.1.
HQ205433 Genomic DNA. Translation: ADP90901.1.
HQ205434 Genomic DNA. Translation: ADP90902.1.
HQ205435 Genomic DNA. Translation: ADP90903.1.
HQ205436 Genomic DNA. Translation: ADP90904.1.
HQ205437 Genomic DNA. Translation: ADP90905.1.
HQ205438 Genomic DNA. Translation: ADP90906.1.
HQ205439 Genomic DNA. Translation: ADP90907.1.
HQ205440 Genomic DNA. Translation: ADP90908.1.
HQ205441 Genomic DNA. Translation: ADP90909.1.
HQ205442 Genomic DNA. Translation: ADP90910.1.
HQ205443 Genomic DNA. Translation: ADP90911.1.
HQ205444 Genomic DNA. Translation: ADP90912.1.
HQ205445 Genomic DNA. Translation: ADP90913.1.
HQ205446 Genomic DNA. Translation: ADP90914.1.
HQ205447 Genomic DNA. Translation: ADP90915.1.
HQ205448 Genomic DNA. Translation: ADP90916.1.
HQ205449 Genomic DNA. Translation: ADP90917.1.
HQ205450 Genomic DNA. Translation: ADP90918.1.
HQ205451 Genomic DNA. Translation: ADP90919.1.
HQ205452 Genomic DNA. Translation: ADP90920.1.
HQ205453 Genomic DNA. Translation: ADP90921.1.
HQ205454 Genomic DNA. Translation: ADP90922.1.
HQ205455 Genomic DNA. Translation: ADP90923.1.
HQ205456 Genomic DNA. Translation: ADP90924.1.
HQ205457 Genomic DNA. Translation: ADP90925.1.
HQ205458 Genomic DNA. Translation: ADP90926.1.
HQ205459 Genomic DNA. Translation: ADP90927.1.
HQ205460 Genomic DNA. Translation: ADP90928.1.
HQ205461 Genomic DNA. Translation: ADP90929.1.
HQ205462 Genomic DNA. Translation: ADP90930.1.
HQ205463 Genomic DNA. Translation: ADP90931.1.
HQ205464 Genomic DNA. Translation: ADP90932.1.
HQ205465 Genomic DNA. Translation: ADP90933.1.
CH471053 Genomic DNA. Translation: EAX00284.1.
RefSeqiNP_573566.2. NM_133259.3.
UniGeneiHs.368084.

Genome annotation databases

GeneIDi10128.
KEGGihsa:10128.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HQ205426 Genomic DNA. Translation: ADP90894.1.
HQ205427 Genomic DNA. Translation: ADP90895.1.
HQ205428 Genomic DNA. Translation: ADP90896.1.
HQ205429 Genomic DNA. Translation: ADP90897.1.
HQ205430 Genomic DNA. Translation: ADP90898.1.
HQ205431 Genomic DNA. Translation: ADP90899.1.
HQ205432 Genomic DNA. Translation: ADP90900.1.
HQ205433 Genomic DNA. Translation: ADP90901.1.
HQ205434 Genomic DNA. Translation: ADP90902.1.
HQ205435 Genomic DNA. Translation: ADP90903.1.
HQ205436 Genomic DNA. Translation: ADP90904.1.
HQ205437 Genomic DNA. Translation: ADP90905.1.
HQ205438 Genomic DNA. Translation: ADP90906.1.
HQ205439 Genomic DNA. Translation: ADP90907.1.
HQ205440 Genomic DNA. Translation: ADP90908.1.
HQ205441 Genomic DNA. Translation: ADP90909.1.
HQ205442 Genomic DNA. Translation: ADP90910.1.
HQ205443 Genomic DNA. Translation: ADP90911.1.
HQ205444 Genomic DNA. Translation: ADP90912.1.
HQ205445 Genomic DNA. Translation: ADP90913.1.
HQ205446 Genomic DNA. Translation: ADP90914.1.
HQ205447 Genomic DNA. Translation: ADP90915.1.
HQ205448 Genomic DNA. Translation: ADP90916.1.
HQ205449 Genomic DNA. Translation: ADP90917.1.
HQ205450 Genomic DNA. Translation: ADP90918.1.
HQ205451 Genomic DNA. Translation: ADP90919.1.
HQ205452 Genomic DNA. Translation: ADP90920.1.
HQ205453 Genomic DNA. Translation: ADP90921.1.
HQ205454 Genomic DNA. Translation: ADP90922.1.
HQ205455 Genomic DNA. Translation: ADP90923.1.
HQ205456 Genomic DNA. Translation: ADP90924.1.
HQ205457 Genomic DNA. Translation: ADP90925.1.
HQ205458 Genomic DNA. Translation: ADP90926.1.
HQ205459 Genomic DNA. Translation: ADP90927.1.
HQ205460 Genomic DNA. Translation: ADP90928.1.
HQ205461 Genomic DNA. Translation: ADP90929.1.
HQ205462 Genomic DNA. Translation: ADP90930.1.
HQ205463 Genomic DNA. Translation: ADP90931.1.
HQ205464 Genomic DNA. Translation: ADP90932.1.
HQ205465 Genomic DNA. Translation: ADP90933.1.
CH471053 Genomic DNA. Translation: EAX00284.1.
RefSeqiNP_573566.2. NM_133259.3.
UniGeneiHs.368084.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000260665.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10128.
KEGGihsa:10128.

Organism-specific databases

CTDi10128.

Phylogenomic databases

eggNOGiKOG4318. Eukaryota.
ENOG410XSG9. LUCA.
KOiK17964.
OMAiPIRQHYF.

Miscellaneous databases

ChiTaRSiLRPPRC. human.
GenomeRNAii10128.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
InterProiIPR002885. Pentatricopeptide_repeat.
IPR033443. PPR_long.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01535. PPR. 3 hits.
PF13812. PPR_3. 1 hit.
PF17177. PPR_long. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00756. PPR. 2 hits.
PROSITEiPS51375. PPR. 11 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Cited for: NUCLEOTIDE SEQUENCE.
  3. "Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing."
    Wang W., Shen P., Thiyagarajan S., Lin S., Palm C., Horvath R., Klopstock T., Cutler D., Pique L., Schrijver I., Davis R.W., Mindrinos M., Speed T.P., Scharfe C.
    Nucleic Acids Res. 39:44-58(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiE5KNY5_HUMAN
AccessioniPrimary (citable) accession number: E5KNY5
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: June 8, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.