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E4ZCY5 (E4ZCY5_NEIL0) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoadenosine phosphosulfate reductase HAMAP-Rule MF_00063

EC=1.8.4.8 HAMAP-Rule MF_00063
Alternative name(s):
3'-phosphoadenylylsulfate reductase HAMAP-Rule MF_00063
PAPS reductase, thioredoxin dependent HAMAP-Rule MF_00063
PAPS sulfotransferase HAMAP-Rule MF_00063
PAdoPS reductase HAMAP-Rule MF_00063
Gene names
Name:cysH HAMAP-Rule MF_00063 EMBL CBN87218.1
Ordered Locus Names:NLA_9920 EMBL CBN87218.1
OrganismNeisseria lactamica (strain 020-06) [Complete proteome] [HAMAP] EMBL CBN87218.1
Taxonomic identifier489653 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite By similarity. HAMAP-Rule MF_00063

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP-Rule MF_00063

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP-Rule MF_00063 SAAS SAAS004511

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00063 SAAS SAAS004511.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily. HAMAP-Rule MF_00063

Sequences

Sequence LengthMass (Da)Tools
E4ZCY5 [UniParc].

Last modified February 8, 2011. Version 1.
Checksum: 21790ACF88B34F20

FASTA24427,987
        10         20         30         40         50         60 
MKIFKPALWK IPPIENGSET ALAEKTETLK QRLHRIAGSH RDARFASSLA AEDMVITDLI 

        70         80         90        100        110        120 
AGENLNIGIF TLDTGLLHAE TLNLLDRIER VYPHMQIKRF QPIREDALHY VESKGRFAFY 

       130        140        150        160        170        180 
DSVEARRECC RIRKIEPLDR AIAGADAWLT GQRREQSATR TELPFAEYDA GRGIGKYNPI 

       190        200        210        220        230        240 
FDWSEHDVWA YILANNVPYN DLYRQGFPSI GCDPCTRPVK AGEDIRAGRW WWEGRNSKEC 


GLHK 

« Hide

References

[1]"Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06."
Bennett J.S., Bentley S.D., Vernikos G.S., Quail M.A., Cherevach I., White B., Parkhill J., Maiden M.C.
BMC Genomics 11:652-652(2010)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 020-06 EMBL CBN87218.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FN995097 Genomic DNA. Translation: CBN87218.1.
RefSeqYP_004048586.1. NC_014752.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCBN87218; CBN87218; NLA_9920.
GeneID10006670.
KEGGnla:NLA_9920.
PATRIC45300320. VBINeiLac170077_1209.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000249395.
KOK00390.

Enzyme and pathway databases

BioCycNLAC489653:GJ91-1021-MONOMER.
UniPathwayUPA00140; UER00206.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00063. CysH.
InterProIPR011798. APS_reductase.
IPR004511. PAPS/APS_Rdtase.
IPR002500. PAPS_reduct.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
PIRSFPIRSF000857. PAPS_reductase. 1 hit.
TIGRFAMsTIGR02055. APS_reductase. 1 hit.
TIGR00434. cysH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameE4ZCY5_NEIL0
AccessionPrimary (citable) accession number: E4ZCY5
Entry history
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: February 19, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)