E4ZB63 (E4ZB63_NEIL0) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP-Rule MF_00301
Short name=HK HAMAP-Rule MF_00301
Short name=HSK HAMAP-Rule MF_00301
EC=2.7.1.39 HAMAP-Rule MF_00301

Gene names

Name:	thrB HAMAP-Rule MF_00301 EMBL CBN86590.1
Ordered Locus Names:	NLA_3500 EMBL CBN86590.1

Organism

Neisseria lactamica (strain 020-06) [Complete proteome] [HAMAP]

Taxonomic identifier

489653 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › Neisseria lactamica

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP-Rule MF_00301 SAAS SAAS005280
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP-Rule MF_00301 SAAS SAAS005280
Sequence similarities	Belongs to the pseudomonas-type ThrB family. HAMAP-Rule MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP-Rule MF_00301 SAAS SAAS005280
Ligand	ATP-binding HAMAP-Rule MF_00301 SAAS SAAS005280 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00301 SAAS SAAS005280 EMBL CBN86590.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	threonine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E4ZB63 [UniParc]. Last modified February 8, 2011. Version 1. Checksum: E0D267A829336E80	FASTA	307	34,005
	10 20 30 40 50 60 MDMSVYTSVS DDEMRGFLDD YDLGEFVSLQ GIAQGITNSN YFLTTTSGRY VLTVFEVLKQ 70 80 90 100 110 120 EELPFFLELN RHLSMKGVAV AAPVARKDGR LDSVLAGKPA CLVACLKGSD TALPTAEQCF 130 140 150 160 170 180 HTGAMLAKMH LAAADFPLEM ENPRYDAWWT EACARLLPVL SQDDAALLRA EIDALKDNLG 190 200 210 220 230 240 NHLPSGIIHA DLFKDNVLLD GGQVSGFIDF YYACRGNFMY DLAIAVNDWA RTADNKLDEA 250 260 270 280 290 300 LEKAFIGGYE GVRPLSAEEK AYFPTAQRAG CIRFWVSRLL DFHFPQAGEM TFIKDPNAFR NLLLSLA

References

[1]

"Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06." Bennett J.S., Bentley S.D., Vernikos G.S., Quail M.A., Cherevach I., White B., Parkhill J., Maiden M.C. BMC Genomics 11:652-652(2010) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 020-06 EMBL CBN86590.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN995097 Genomic DNA. Translation: CBN86590.1.
RefSeq	YP_004047980.1. NC_014752.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CBN86590; CBN86590; NLA_3500.
GeneID	10007374.
KEGG	nla:NLA_3500.
PATRIC	45298626. VBINeiLac170077_0403.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000004810.
KO	K02204.
Enzyme and pathway databases
BioCyc	NLAC489653:GJ91-364-MONOMER.
UniPathway	UPA00050; UER00064.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2.
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. thrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

E4ZB63_NEIL0

Accession

Primary (citable) accession number: E4ZB63

Entry history

Integrated into UniProtKB/TrEMBL:	February 8, 2011
Last sequence update:	February 8, 2011
Last modified:	May 29, 2013
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)