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E4ZAX6

- E4ZAX6_NEIL0

UniProt

E4ZAX6 - E4ZAX6_NEIL0

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Protein

Phosphoenolpyruvate carboxylase

Gene
ppc, NLA_2620
Organism
Neisseria lactamica (strain 020-06)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei158 – 1581 By similarityUniRule annotation
Active sitei586 – 5861 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciNLAC489653:GJ91-275-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:NLA_2620Imported
OrganismiNeisseria lactamica (strain 020-06)Imported
Taxonomic identifieri489653 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesNeisseriaceaeNeisseria
ProteomesiUP000008723: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E4ZAX6-1 [UniParc]FASTAAdd to Basket

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MRHLGYIYNI YGKRERKIMQ LHILNNPKDA ALAADAEFLK QSLFNLLHEE    50
ASPLVVETVK LLSTSDDSAA LIEKVLPQLD ERQTYDLTLA CGLFAQILNI 100
AEDVHHERRR QIHEDAGHNA AEGSLTETVR RLKAGKADDK SVQRQLDNTS 150
VTAVLTAHPT EVQRQTVLNF NRRIRALLPQ RERCTNADAL ARLRREIDTV 200
LLGLWQTSET RRHKLSVNDE INNGVSIFPM SFFEALPKLY RKMEHDFQTA 250
YPDVRVPDIL KIGGWIGGDR DGNPFVSAET LRFAFRRHAD AVFRFYRGEL 300
DKLYRELPLS IRRVKVNGDV MALSDKSPDE EIARTEEPYR RAIAYIMARA 350
MGKARALGLG MGCKFGFLEP YASAQEFLDD LKKLQRSLID NGSRLLAEGR 400
LADLIRSVSV FGFHMMPLDL RQHAGKHADV VAELFQHAGL EDYNSLNEEQ 450
KQAALLRELS HQRPLYSPFI TYSDHTRHEL AIFNEARKIK DEFGEDAVTQ 500
SIISNCEQPG DLLALALLLK ESGLLAVENG KPKSRINIVP LFETIEALEN 550
ACPVMETMFR LDWYGALLES RGNIQEIMLG YSDSNKDGGY VTSSWCLYQA 600
ELGLVELFKK YGVRMRLFHG RGGSVGRGGG PSYQAILAQP AGSVAGQIRI 650
TEQGEVITAK YADPGNAQRN LETLVAATLE AGIPTDKKDP DAKLMQALSD 700
VSFKYYRELI THPDFIDYFL QTSPIQEIAT LNLGSRPASR KTLARIQDLR 750
AIPWVFSWMQ NRLMLPAWYG FGSAVETLCE GSPETLAALR GHARNNPFFQ 800
AMLSNMEQVM AKTDITLAEN YAGLSESPDK AKIIFGMIKE EYRRSRKALL 850
DLLQTEELLR DNRSLARSLA LRIPYLNALN GLQVAMLKRL RKEPDNPHAL 900
LMVHLTINGV AQGLRNTG 918
Length:918
Mass (Da):103,357
Last modified:February 8, 2011 - v1
Checksum:iE9694AEC19E3969A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN995097 Genomic DNA. Translation: CBN86503.1.
RefSeqiYP_004047893.1. NC_014752.1.

Genome annotation databases

EnsemblBacteriaiCBN86503; CBN86503; NLA_2620.
GeneIDi10007275.
KEGGinla:NLA_2620.
PATRICi45298428. VBINeiLac170077_0305.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN995097 Genomic DNA. Translation: CBN86503.1 .
RefSeqi YP_004047893.1. NC_014752.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CBN86503 ; CBN86503 ; NLA_2620 .
GeneIDi 10007275.
KEGGi nla:NLA_2620.
PATRICi 45298428. VBINeiLac170077_0305.

Phylogenomic databases

HOGENOMi HOG000238647.
KOi K01595.

Enzyme and pathway databases

BioCyci NLAC489653:GJ91-275-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Independent evolution of the core and accessory gene sets in the genus Neisseria: insights gained from the genome of Neisseria lactamica isolate 020-06."
    Bennett J.S., Bentley S.D., Vernikos G.S., Quail M.A., Cherevach I., White B., Parkhill J., Maiden M.C.
    BMC Genomics 11:652-652(2010)
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 020-06Imported.

Entry informationi

Entry nameiE4ZAX6_NEIL0
AccessioniPrimary (citable) accession number: E4ZAX6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 8, 2011
Last sequence update: February 8, 2011
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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